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Wnt/beta-catenin

Wnt/beta-catenin

Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.

Found 66 products of "Wnt/beta-catenin"

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  • β-catenin modulator IIa-661

    CAS:
    <p>β-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity.</p>
    Formula:C19H23ClN2O3S
    Purity:99.58%
    Color and Shape:Soild
    Molecular weight:394.92
  • WIC1

    CAS:
    <p>2H-1-Benzopyran-3-carboxamide, N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo- is a compound that is potential for the treatment of tumours.</p>
    Formula:C22H23N3O3
    Purity:99.82%
    Color and Shape:Soild
    Molecular weight:377.44
  • Blosozumab

    CAS:
    <p>Blosozumab (LY2541546) is a monoclonal antibody targeting sclerostin that promotes bone formation, used in the research of osteoporosis.</p>
    Purity:98.7% (SEC-HPLC) - 99.53% (SEC-HPLC)
    Color and Shape:Liquid
  • 1(R),2(S)-epoxy Cannabidiol

    CAS:
    <p>1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analog of phytocannabinoids, exhibiting significant inhibitory activity on the Wnt/β-catenin pathway. It holds potential for research as a neuroprotective agent.</p>
    Formula:C21H30O3
    Color and Shape:Solid
    Molecular weight:330.46
  • YW2036

    CAS:
    <p>YW2036 is an inhibitor of Wnt signaling pathway.</p>
    Formula:C20H16N4O
    Purity:99.94%
    Color and Shape:Soild
    Molecular weight:328.37
  • IWP-3

    CAS:
    <p>IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1γ3 and CK1ε, but does not inhibit CK1α [1] [2].</p>
    Formula:C22H17FN4O2S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:484.59
  • FH535

    CAS:
    <p>FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.</p>
    Formula:C13H10Cl2N2O4S
    Purity:98.25% - 99.5%
    Color and Shape:Solid
    Molecular weight:361.2
  • Cardiogenol C

    CAS:
    <p>Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.</p>
    Formula:C13H16N4O2
    Purity:98.46%
    Color and Shape:Solid
    Molecular weight:260.29
  • Cardiogenol C hydrochloride

    CAS:
    <p>Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).</p>
    Formula:C13H17ClN4O2
    Purity:99.89% - 99.94%
    Color and Shape:Solid
    Molecular weight:296.75
  • IWR-1

    CAS:
    <p>IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).</p>
    Formula:C25H19N3O3
    Purity:99.19% - 99.82%
    Color and Shape:Solid
    Molecular weight:409.44
  • LF3

    CAS:
    <p>LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 (IC50 &lt; 2 μM)</p>
    Formula:C20H24N4O2S2
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:416.56
  • SKL2001

    CAS:
    <p>SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction.</p>
    Formula:C14H14N4O3
    Purity:97.46% - 99.5%
    Color and Shape:Solid
    Molecular weight:286.29
  • Adavivint

    CAS:
    <p>Adavivint (Adavivint (SM04690)) (SM04690) is a Wnt pathway inhibitor.</p>
    Formula:C29H24FN7O
    Purity:98.27% - 98.6%
    Color and Shape:Solid
    Molecular weight:505.55
  • Wnt-C59

    CAS:
    <p>Wnt-C59 (C59)(C59) is a highly effective and specific Wnt signaling antagonis with PORCN enzymatic activity.</p>
    Formula:C25H21N3O
    Purity:99.56% - 99.95%
    Color and Shape:Solid
    Molecular weight:379.45
  • Teplinovivint

    CAS:
    <p>Teplinovivint is a potent inhibitor of the Wnt/β-catenin signaling pathway, demonstrating anti-inflammatory properties with potential utility in tendinopathy</p>
    Formula:C25H26N6O2
    Purity:97.21%
    Color and Shape:Solid
    Molecular weight:442.51
  • iCRT 14

    CAS:
    <p>iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).</p>
    Formula:C21H17N3O2S
    Purity:99.8% - 99.97%
    Color and Shape:Solid
    Molecular weight:375.44
  • BML-284

    CAS:
    <p>BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.</p>
    Formula:C19H18N4O3
    Purity:99.91% - 99.921%
    Color and Shape:Solid
    Molecular weight:350.37
  • KY02111

    CAS:
    <p>KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.</p>
    Formula:C18H17ClN2O3S
    Purity:97.71% - 98.3%
    Color and Shape:Solid
    Molecular weight:376.86
  • β-catenin-IN-2

    CAS:
    <p>β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.</p>
    Formula:C15H14FN3
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:255.29
  • exo-IWR-1

    CAS:
    <p>exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin</p>
    Formula:C25H19N3O3
    Purity:97.41%
    Color and Shape:Solid
    Molecular weight:409.44