Wnt/beta-catenin
Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.
Found 60 products of "Wnt/beta-catenin"
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LP-922056
CAS:LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.
Formula:C11H9ClN2O2S2Purity:99.84%Color and Shape:SolidMolecular weight:300.78Foxy-5
CAS:Foxy-5 is a wnt5a peptide mimeticFormula:C26H42N6O12S2Purity:98%Color and Shape:SolidMolecular weight:694.77IWP-3
CAS:IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1γ3 and CK1ε, but does not inhibit CK1α [1] [2].Formula:C22H17FN4O2S3Purity:98%Color and Shape:SolidMolecular weight:484.59WAY-262611
CAS:WAY262611 is a Wnt/β-catenin agonist and an inhibitor of Dkk1. It increases bone formation rate with EC50 of 0.63 μM in TCF-luciferase assay.Formula:C20H22N4Purity:98.09% - 99.09%Color and Shape:SolidMolecular weight:318.42Cardiogenol C
CAS:Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.Formula:C13H16N4O2Purity:98.46%Color and Shape:SolidMolecular weight:260.29Cardiogenol C hydrochloride
CAS:Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).Formula:C13H17ClN4O2Purity:99.89% - 99.94%Color and Shape:SolidMolecular weight:296.75IWR-1
CAS:IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).Formula:C25H19N3O3Purity:99.19% - 99.82%Color and Shape:SolidMolecular weight:409.44LF3
CAS:LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 (IC50 < 2 μM)Formula:C20H24N4O2S2Purity:99.63%Color and Shape:SolidMolecular weight:416.56SKL2001
CAS:SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction.Formula:C14H14N4O3Purity:97.46% - 99.99%Color and Shape:SolidMolecular weight:286.29Ref: TM-T6989
5mg38.00€10mg57.00€25mg102.00€50mg175.00€100mg321.00€200mg484.00€500mg755.00€1mL*10mM (DMSO)63.00€Adavivint
CAS:Adavivint (Adavivint (SM04690)) (SM04690) is a Wnt pathway inhibitor.
Formula:C29H24FN7OPurity:98.27% - 98.6%Color and Shape:SolidMolecular weight:505.55Teplinovivint
CAS:Teplinovivint is a potent inhibitor of the Wnt/β-catenin signaling pathway, demonstrating anti-inflammatory properties with potential utility in tendinopathyFormula:C25H26N6O2Purity:97.21%Color and Shape:SolidMolecular weight:442.51iCRT 14
CAS:iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).Formula:C21H17N3O2SPurity:99.8% - 99.97%Color and Shape:SolidMolecular weight:375.44BML-284
CAS:BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.Formula:C19H18N4O3Purity:99.91% - 99.921%Color and Shape:SolidMolecular weight:350.37Ref: TM-T3144
5mg57.00€10mg84.00€25mg133.00€50mg240.00€100mg405.00€200mg583.00€500mg888.00€1mL*10mM (DMSO)63.00€KY02111
CAS:KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.Formula:C18H17ClN2O3SPurity:97.71% - 98.3%Color and Shape:SolidMolecular weight:376.86β-catenin-IN-2
CAS:β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.Formula:C15H14FN3Purity:99.93%Color and Shape:SolidMolecular weight:255.29Ref: TM-T9696
1mg90.00€5mg215.00€10mg340.00€25mg575.00€50mg822.00€100mg1,108.00€500mg2,242.00€1mL*10mM (DMSO)250.00€exo-IWR-1
CAS:exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin
Formula:C25H19N3O3Purity:97.41%Color and Shape:SolidMolecular weight:409.44Wnt pathway activator 1
CAS:Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM.Formula:C18H16O4Purity:99.93%Color and Shape:SolidMolecular weight:296.32Ref: TM-T17256
2mg33.00€5mg49.00€10mg75.00€25mg124.00€50mg200.00€100mg299.00€200mg430.00€1mL*10mM (DMSO)50.00€WAY 316606
CAS:WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt.Formula:C18H19F3N2O4S2Purity:99.65%Color and Shape:SolidMolecular weight:448.48IWP-O1
CAS:IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.Formula:C26H20N6OPurity:99.12%Color and Shape:SolidMolecular weight:432.48Ref: TM-T5342
2mg39.00€5mg64.00€10mg101.00€25mg163.00€50mg226.00€100mg320.00€200mg459.00€1mL*10mM (DMSO)70.00€Tegatrabetan
CAS:Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.Formula:C28H36N4O6S2Purity:98.01% - 99.18%Color and Shape:SolidMolecular weight:588.74Ref: TM-T5642
1mg40.00€2mg52.00€5mg85.00€10mg124.00€25mg210.00€50mg334.00€100mg565.00€1mL*10mM (DMSO)96.00€
