Stem Cells
Stem cell inhibitors are compounds that specifically target stem cells and their signaling pathways, affecting their ability to self-renew and differentiate. These inhibitors are crucial in research focused on controlling stem cell behavior, understanding developmental processes, and developing therapies for diseases like cancer, where stem cells are thought to play a key role. At CymitQuimica, we offer a variety of stem cell inhibitors to support your research in regenerative medicine, developmental biology, and oncology.
Found 225 products of "Stem Cells"
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Sonidegib diphosphate
CAS:Sonidegib diphosphate (LDE225 diphosphate) is a selective antagonist of Smo that inhibits murine Smo and human Smo.Cost-effective and quality-assured.Formula:C26H32F3N3O11P2Purity:99.48% - >99.99%Color and Shape:SolidMolecular weight:681.49Rat sCD14(SolubleCluster of Differentiation 14) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat sCD14. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat sCD14. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat sCD14, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat sCD14 in the samples is then determined by comparing the OD of the samples to the standard curve.TEAD-IN-16
TEAD-IN-16 (compound BC-011) is a potent inhibitor of TEAD, with an IC50 of 72.43 μM. This compound plays a significant role in cancer research.
Formula:C16H14F3NO3Molecular weight:325.09258MR24
CAS:MR24 is a derivative of G-5555 and acts as an inhibitor of mammalian STE20-like (MST) kinases. It selectively targets MST3 and MST4, with EC50 values of 57 nM and 583 nM, respectively.Formula:C26H29ClN6O3Molecular weight:509.00YAP/TEAD-IN-1
YAP/TEAD-IN-1 (compound 4) is a potent inhibitor of YAP and TEAD, exhibiting antioxidant properties. It demonstrates antiproliferative effects on tumor cells while showing minimal cytotoxic activity towards normal human cells.
Formula:C32H30N8OColor and Shape:SolidMolecular weight:542.634STAT3-IN-34
STAT3-IN-34 (Compound 15E) acts as a STAT3 inhibitor, blocking both the nuclear translocation and the transcriptional regulator activity of STAT3. It effectively inhibits HaCaT cell proliferation with an IC50 value of 0.008 μM. Additionally, STAT3-IN-34 reduces IL-17A expression and mitigates Imiquimod-induced psoriasis in mouse models.Formula:C19H16N2O4SColor and Shape:SolidMolecular weight:368.41Wnt/β-catenin agonist 3
CAS:Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist.
Formula:C16H15ClN4O2Purity:99.52%Color and Shape:SolidMolecular weight:330.77Epigenetics Compound Library
Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for newColor and Shape:Odour SolidRef: TM-L1200
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquirePlant 14-3-3-IN-1
Plant 14-3-3-IN-1 (Compound 2) is an inhibitor of the Arabidopsis thaliana 14-3-3 protein, with an IC50 of 1.21 μM. It exhibits varying inhibitory activity against different 14-3-3 isoforms and promotes the closure of leaf stomata.Formula:C22H19NO7SMolecular weight:441.08822STX-0119
CAS:STX-0119 is a selective, orally active STAT3 dimerization inhibitor. STX-0119 inhibits STAT3 transcription with an IC50 of 74 μM.
Formula:C22H14N4O3Purity:99.61%Color and Shape:SolidMolecular weight:382.37P17 Peptide
CAS:P17 Peptide, a human TGF-β1 inhibitory peptide, effectively blocks the activity of woodchuck TGF-β1.Formula:C95H139N27O21Color and Shape:SolidMolecular weight:1995.29Wnt/Hedgehog/Notch Compound Library
A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
Color and Shape:Odour SolidYAP-TEAD-IN-1 acetate
YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.Formula:C95H148ClN23O23S2Purity:98.11% - 99.57%Color and Shape:SoildMolecular weight:2079.92WIC1
CAS:2H-1-Benzopyran-3-carboxamide, N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo- is a compound that is potential for the treatment of tumours.
Formula:C22H23N3O3Purity:99.82%Color and Shape:SoildMolecular weight:377.44LP-922056
CAS:LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.
Formula:C11H9ClN2O2S2Purity:99.84%Color and Shape:SolidMolecular weight:300.78ROCK2-IN-9
ROCK2-IN-9 (compound 7u), a selective ROCK2 inhibitor with an IC50 value of 36.8 nM, demonstrates anticancer properties by impeding cancer cell migration and invasion. This action is achieved through the regulation of various actin cytoskeleton cellular activities. It holds potential for use in breast cancer research.Formula:C28H30N8O2Color and Shape:SolidMolecular weight:510.59BAY 593
CAS:BAY 593 functions as an inhibitor of geranylgeranyltransferase-I (GGTase-I), effectively preventing the activation of Rho-GTPases and consequently inactivating YAP1/TAZ signaling pathways. It has been shown to inhibit tumor growth dose-dependently in xenograft mouse models, exhibiting IC50 values of 38.4 nM in MT-1080 cells and 564 nM in MDA-MB-231 cells, as well as in PXF 541 xenografts.Formula:C26H32ClF3N2O3Color and Shape:SolidMolecular weight:512.99Super-TDU (1-31) (TFA)
Super-TDU (1-31) TFA, a peptide, inhibits YAP-TEAD; it has strong anti-tumor effects in gastric cancer models.Formula:C141H218N40O48·C2HF3O2Color and Shape:SolidMolecular weight:3355.5Fresolimumab
CAS:Fresolimumab (GC1008) is a human monoclonal antibody targeting active TGFβ1, TGFβ2, TGFβ3, studied for cancer and focal segmental glomerulosclerosis.Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:144.4 kDaSLLK, Control Peptide for TSP1 Inhibitor(TFA)
CAS:SLLK is a control peptide for LSKL.
Formula:C21H41N5O6Purity:98%Color and Shape:SolidMolecular weight:459.58
