Gamma-secretase

21 products on this category.

Product data	Purity	Price range	Estimated delivery
CB-103 REF: TM-T12246CAS: 218457-67-1	99.69%	46.00 €~128.00 €	Fri 09 Aug 24
Rovalpituzumab REF: TM-T76698CAS: 1613313-01-1	SDS-PAGE:95% SEC-HPLC:95%	171.00 €~1,968.00 €	Mon 12 Aug 24
CIA-1 (Free base) REF: TM-T71534LCAS: 452087-38-6	98%	56.00 €~3,415.00 €	Mon 12 Aug 24
Demcizumab REF: TM-T76788CAS: 1243262-17-0	SDS-PAGE:95% SEC-HPLC:95%	347.00 €~1,392.00 €	Mon 12 Aug 24
RBPJ Inhibitor-1 REF: TM-T35566CAS: 2682114-39-0	99.58%	40.00 €~562.00 €	Mon 12 Aug 24
BMS-906024 REF: TM-T14680CAS: 1401066-79-2	99.87%	533.00 €~4,601.00 €	Mon 12 Aug 24
Legumain inhibitor 1 REF: TM-T39905CAS: 2361157-34-6	98.14%	278.00 €	Mon 12 Aug 24
RO7185876 REF: TM-T39702CAS: 2226038-71-5	98.63%	276.00 €~1,862.00 €	Mon 12 Aug 24
γ-Secretase modulator 13 REF: TM-T62263CAS: 1353570-40-7	99.68%	274.00 €~2,336.00 €	Mon 12 Aug 24
IMR-1A REF: TM-T3540CAS: 331862-41-0	97.1%	73.00 €~2,270.00 €	Fri 16 Aug 24
IMR-1 REF: TM-T6861CAS: 310456-65-6	98.38%	40.00 €~1,072.00 €	Fri 16 Aug 24
LY900009 REF: TM-T9015CAS: 209984-68-9	98.97%	59.00 €~723.00 €	Fri 16 Aug 24
JLK6 REF: TM-T21890CAS: 62252-26-0	96.50%	129.00 €~2,362.00 €	Fri 16 Aug 24
FLI-06 REF: TM-T3075CAS: 313967-18-9	100%	35.00 €~1,161.00 €	Fri 16 Aug 24
γ-secretase modulator 1 REF: TM-T11358CAS: 1172637-87-4	99.75%	To inquire	Fri 27 Sep 24
CIA-1 hcl(452087-38-6 Free base) REF: TM-T71534CAS: 1049691-47-5	99.02%	373.00 €~2,337.00 €	Fri 27 Sep 24
JI051 REF: TM-T11718CAS: 2234281-75-3	- - -	64.00 €~2,340.00 €	Fri 27 Sep 24
Aβ42-IN-2 REF: TM-T9641CAS: 1914989-80-2	100%	63.00 €~1,377.00 €	Fri 27 Sep 24
Aβ-IN-1 REF: TM-T63208CAS: 2766509-32-2	99.14%	326.00 €~4,551.00 €	Fri 27 Sep 24
ELN318463 racemate REF: TM-T11178LCAS: 851599-82-1	99.73%	159.00 €~1,629.00 €	Fri 27 Sep 24
BMS-983970 REF: TM-T14683CAS: 1584713-87-0	- - -	135.00 €~1,863.00 €	Fri 11 Oct 24

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CB-103

CAS:218457-67-1

CB-103 is a orally active inhibitor of notch signaling pathway, with anti-tumor activity.

Formula:

C₁₅H₁₈N₂O

Purity:

99.69%

Color and Shape:

Solid

Molecular weight:

242.32

Ref: TM-T12246

1ml		51.00 €
10mg		46.00 €
50mg		49.00 €
100mg		59.00 €
200mg		86.00 €
500mg		128.00 €

Estimated delivery in United States, on Friday 9 Aug 2024

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Rovalpituzumab

CAS:1613313-01-1

Rovalpituzumab: humanized antibody against DLL3, forms ADCs, treats small cell lung cancer.

Purity:

SDS-PAGE:95% SEC-HPLC:95%

Color and Shape:

Solid

Ref: TM-T76698

1mg		171.00 €
5mg		441.00 €
10mg		702.00 €
25mg		1,093.00 €
50mg		1,458.00 €
100mg		1,968.00 €

Estimated delivery in United States, on Monday 12 Aug 2024

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CIA-1 (Free base)

CAS:452087-38-6

CIA-1, a COUP-TFII inhibitor, has IC50 of 1.2-7.6 μM in prostate cancer cells; inhibits tumor …

Formula:

C₁₇H₁₉N₃O₂S

Purity:

98%

Color and Shape:

Solid

Molecular weight:

329.42

Ref: TM-T71534L

1mg		56.00 €
5mg		119.00 €
10mg		183.00 €
25mg		368.00 €
50mg		575.00 €
100mg		884.00 €

Estimated delivery in United States, on Monday 12 Aug 2024

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Demcizumab

CAS:1243262-17-0

Demcizumab (OMP 21M18), an anti-DLL4 antibody, inhibits the Notch pathway and fights various cancers solo …

Purity:

SDS-PAGE:95% SEC-HPLC:95%

Color and Shape:

Solid

Molecular weight:

145.65 (kDa)

Ref: TM-T76788

1mg		347.00 €
5mg		869.00 €
10mg		1,392.00 €

Estimated delivery in United States, on Monday 12 Aug 2024

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RBPJ Inhibitor-1

CAS:2682114-39-0

RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively …

Formula:

C₁₇H₁₄FN₃O₂

Purity:

99.58%

Color and Shape:

Solid

Molecular weight:

311.31

Ref: TM-T35566

1mg		40.00 €
1ml		87.00 €
2mg		53.00 €
5mg		87.00 €
10mg		134.00 €
25mg		226.00 €
50mg		390.00 €
100mg		562.00 €

Estimated delivery in United States, on Monday 12 Aug 2024

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BMS-906024

CAS:1401066-79-2

BMS-906024 (Osugacestat) is a gamma secretase inhibitor, a Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity.

Formula:

C₂₆H₂₆F₆N₄O₃

Purity:

99.87%

Color and Shape:

Solid

Molecular weight:

556.5

Ref: TM-T14680

1mg		533.00 €
2mg		743.00 €
5mg		1,113.00 €
10mg		1,688.00 €
25mg		2,527.00 €
50mg		3,413.00 €
100mg		4,601.00 €

Estimated delivery in United States, on Monday 12 Aug 2024

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Legumain inhibitor 1

CAS:2361157-34-6

Legumain inhibitor 1 is a highly potent and specific Legumain inhibitor with potential anticancer activity …

Formula:

C₂₃H₂₅N₅O₄S

Purity:

98.14%

Color and Shape:

Solid

Molecular weight:

467.54

Ref: TM-T39905

1mg 278.00 €

Estimated delivery in United States, on Monday 12 Aug 2024

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RO7185876

CAS:2226038-71-5

RO7185876 is a selective gamma secretase modulator, which can be used in the study of …

Formula:

C₂₅H₂₈F₃N₇

Purity:

98.63%

Color and Shape:

Solid

Molecular weight:

483.532

Ref: TM-T39702

1mg		276.00 €
5mg		679.00 €
10mg		928.00 €
25mg		1,430.00 €
50mg		1,862.00 €

Estimated delivery in United States, on Monday 12 Aug 2024

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γ-Secretase modulator 13

CAS:1353570-40-7

γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that can be used to study Alzheimer's …

Formula:

C₂₂H₂₃FN₆S

Purity:

99.68%

Color and Shape:

Solid

Molecular weight:

422.52

Ref: TM-T62263

1mg		274.00 €
5mg		675.00 €
10mg		923.00 €
25mg		1,421.00 €
50mg		1,850.00 €
100mg		2,336.00 €

Estimated delivery in United States, on Monday 12 Aug 2024

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IMR-1A

CAS:331862-41-0

IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting …

Formula:

C₁₃H₁₁NO₅S₂

Purity:

97.1%

Color and Shape:

Solid

Molecular weight:

325.36

Ref: TM-T3540

1mg		73.00 €
1ml		161.00 €
5mg		157.00 €
10mg		244.00 €
25mg		365.00 €
50mg		491.00 €
100mg		738.00 €

Estimated delivery in United States, on Friday 16 Aug 2024

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IMR-1

CAS:310456-65-6

IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of …

Formula:

C₁₅H₁₅NO₅S₂

Purity:

98.38%

Color and Shape:

Solid

Molecular weight:

353.41

Ref: TM-T6861

1ml		87.00 €
2mg		40.00 €
5mg		57.00 €
10mg		92.00 €
25mg		171.00 €
50mg		295.00 €
100mg		485.00 €
500mg		1,072.00 €

Estimated delivery in United States, on Friday 16 Aug 2024

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LY900009

CAS:209984-68-9

LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase …

Formula:

C₂₃H₂₇N₃O₄

Purity:

98.97%

Color and Shape:

Solid

Molecular weight:

409.48

Ref: TM-T9015

1mg		59.00 €
1ml		153.00 €
2mg		84.00 €
5mg		124.00 €
10mg		189.00 €
25mg		339.00 €
50mg		501.00 €
100mg		723.00 €

Estimated delivery in United States, on Friday 16 Aug 2024

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JLK6

CAS:62252-26-0

JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signalling

Formula:

C₁₀H₈ClNO₃

Purity:

96.50%

Color and Shape:

Solid

Molecular weight:

225.63

Ref: TM-T21890

1mg		129.00 €
1ml		270.00 €
5mg		255.00 €
10mg		365.00 €
25mg		611.00 €
50mg		870.00 €
100mg		1,183.00 €
500mg		2,362.00 €

Estimated delivery in United States, on Friday 16 Aug 2024

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FLI-06

CAS:313967-18-9

FLI-06 is a Notch signaling inhibitor (EC50: 2.3 μM).

Formula:

C₂₅H₃₀N₂O₅

Purity:

100%

Color and Shape:

Solid

Molecular weight:

438.52

Ref: TM-T3075

1mg		35.00 €
1ml		82.00 €
2mg		52.00 €
5mg		73.00 €
10mg		97.00 €
25mg		169.00 €
50mg		307.00 €
100mg		532.00 €
500mg		1,161.00 €

Estimated delivery in United States, on Friday 16 Aug 2024

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γ-secretase modulator 1

CAS:1172637-87-4

gamma-secretase modulator 1 is a modulator of γ secretase and can be used in studies …

Formula:

C₂₄H₂₄N₄OS

Purity:

99.75%

Color and Shape:

Solid

Molecular weight:

416.54

Ref: TM-T11358

1mg		40.00 €
5mg		81.00 €
10mg		130.00 €
25mg		246.00 €
50mg		365.00 €
100mg		To inquire
500mg		To inquire

Estimated delivery in United States, on Friday 27 Sep 2024

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CIA-1 hcl(452087-38-6 Free base)

CAS:1049691-47-5

CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM …

Formula:

C₁₇H₂₀ClN₃O₂S

Purity:

99.02%

Color and Shape:

Solid

Molecular weight:

365.88

Ref: TM-T71534

10mg		373.00 €
50mg		1,556.00 €

Estimated delivery in United States, on Friday 27 Sep 2024

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JI051

CAS:2234281-75-3

JI051 has anti-tumor effects and can interact with PHB2 to inhibit the proliferation of HEK293 …

Formula:

C₂₂H₂₄N₂O₃

Color and Shape:

Solid

Molecular weight:

364.44

Ref: TM-T11718

1mg		64.00 €
2mg		90.00 €

Estimated delivery in United States, on Friday 27 Sep 2024

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Aβ42-IN-2

CAS:1914989-80-2

Aβ42-IN-2 is a γ-secretase modulator. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ …

Formula:

C₂₄H₂₆N₆O₂

Purity:

100%

Color and Shape:

Solid

Molecular weight:

430.5

Ref: TM-T9641

1mg		63.00 €
1ml		154.00 €
2mg		92.00 €
5mg		138.00 €
10mg		211.00 €
25mg		351.00 €
50mg		498.00 €
100mg		687.00 €
500mg		1,377.00 €

Estimated delivery in United States, on Friday 27 Sep 2024

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Aβ-IN-1

CAS:2766509-32-2

Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM).

Formula:

C₃₅H₄₉N

Purity:

99.14%

Color and Shape:

Solid

Molecular weight:

483.77

Ref: TM-T63208

1mg		326.00 €
5mg		772.00 €
10mg		1,056.00 €
25mg		1,483.00 €
50mg		1,846.00 €
100mg		2,322.00 €
500mg		4,551.00 €

Estimated delivery in United States, on Friday 27 Sep 2024

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ELN318463 racemate

CAS:851599-82-1

ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor …

Formula:

C₁₉H₂₀BrClN₂O₃S

Purity:

99.73%

Color and Shape:

Solid

Molecular weight:

471.8

Ref: TM-T11178L

1mg		159.00 €
1ml		445.00 €
5mg		384.00 €
10mg		603.00 €
25mg		888.00 €
50mg		1,210.00 €
100mg		1,629.00 €

Estimated delivery in United States, on Friday 27 Sep 2024

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BMS-983970

CAS:1584713-87-0

BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.

Formula:

C₂₆H₂₆F₄N₄O₃

Color and Shape:

Solid

Molecular weight:

518.5

Ref: TM-T14683

1ml		374.00 €
2mg		186.00 €
5mg		325.00 €
25mg		1,410.00 €
50mg		1,854.00 €
100mg		1,863.00 €

Estimated delivery in United States, on Friday 11 Oct 2024

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