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c-Fms

c-Fms

c-Fms inhibitors target the Colony Stimulating Factor-1 Receptor (c-Fms), a tyrosine kinase involved in the regulation of macrophages and other immune cells. c-Fms signaling plays a role in the proliferation, differentiation, and survival of these cells. Dysregulation of c-Fms is associated with diseases such as cancer, inflammatory conditions, and osteoporosis. At CymitQuimica, we offer c-Fms inhibitors to support your research in immunology, oncology, and inflammatory diseases.

Found 108 products of "c-Fms"

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  • CymitQuimica logo
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    Anumigilimab

    CAS:
    <p>Anumigilimab (CSL-324) is a fully human therapeutic anti-G-CSFR antibody with potential anti-tumor activity for the study of inflammation.</p>
    Purity:95.75% (SEC-HPLC) - 98.43% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:143.86 kDa

    Ref: TM-T76908

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    Lenzilumab

    CAS:
    <p>Lenzilumab (KB 003) is a humanized GM-CSF neutralizing antibody for the study of COVID-19.</p>
    Purity:98.9% (SDS-PAGE); 98.5% (SEC-HPLC) - 98.9% (SDS-PAGE); 98.5% (SEC-HPLC)
    Color and Shape:Liquid

    Ref: TM-T76751

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    Namilumab

    CAS:
    <p>Namilumab (AMG203) is a humanised IgG1 monoclonal antibody that neutralises GM-CSF. rheumatoid arthritis and active axial spondyloarthritis.</p>
    Purity:95%
    Color and Shape:Liquid

    Ref: TM-T76820

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    Trabikibart

    CAS:
    <p>Trabikibart (CSL311) is a human βc-specific antibody inhibiting IL-3, GM-CSF and IL-5, regulating eosinophil survival in chronic inflammatory disease research.</p>
    Purity:95% - 95%
    Color and Shape:Liquid

    Ref: TM-T80959

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    Cabiralizumab

    CAS:
    <p>Cabiralizumab is an anti-CSF1R monoclonal antibody that enhances T cell infiltration, inhibits osteoclasts, and is used in RA and immune-oncology research.</p>
    Purity:95% - 95%
    Color and Shape:Liquid

    Ref: TM-T76786

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    Anti-Mouse GM-CSF Antibody (MP1-22E9)

    <p>Anti-Mouse GM-CSF Antibody is a rat-derived IgG2a isotype inhibitor that targets mouse granulocyte-macrophage colony-stimulating factor (GM-CSF).</p>
    Purity:98%
    Color and Shape:Odour Liquid

    Ref: TM-T80585

  • CSF1R-IN-19
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    CSF1R-IN-19

    CAS:
    <p>CSF1R-IN-19 is a robust inhibitor of CSF1R that influences the exchange of inflammatory factors between TAMs and glioma cells. It holds potential for cancer research [1].</p>
    Formula:C20H27N7O
    Color and Shape:Solid
    Molecular weight:381.47

    Ref: TM-T86099

  • Sotuletinib dihydrochloride
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    Sotuletinib dihydrochloride

    CAS:
    <p>Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable inhibitor specifically targeting CSF1-R with an IC50 of 1 nM.</p>
    Formula:C20H24Cl2N4O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:471.4

    Ref: TM-T78603

  • c-Fms-IN-9
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    c-Fms-IN-9

    CAS:
    <p>c-Fms-IN-9 inhibits c-FMS/uFMS and uKIT with IC50 &lt;0.01μM and 0.1-1μM, from patent WO2014145023A1.</p>
    Formula:C21H23N7O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:405.45

    Ref: TM-T10648

  • Leustroducsin A
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    Leustroducsin A

    CAS:
    <p>Leustroducsin A is an inducer of colony-stimulating factors (CSFs) extracted from Streptomyces platensis SANK 60191.</p>
    Formula:C32H52NO10P
    Color and Shape:Solid
    Molecular weight:641.73

    Ref: TM-T32686

  • c-Fms-IN-7
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    c-Fms-IN-7

    CAS:
    <p>c-Fms-IN-7 is a cFMS inhibitor (IC50: 18.5 nM).</p>
    Formula:C26H24N6OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.57

    Ref: TM-T10646

  • c-Fms-IN-8
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    c-Fms-IN-8

    CAS:
    <p>c-Fms-IN-8 is a colony-stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor (IC50: 9.1 nM). It is compound 4a in the reference.</p>
    Formula:C27H30N2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:462.54

    Ref: TM-T10647

  • JNJ-28312141
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    JNJ-28312141

    CAS:
    <p>JNJ-28312141: oral CSF1R/FLT3 inhibitor, potential for treating acute myeloid leukemia, tumors, and bone events.</p>
    Formula:C26H32N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:460.57

    Ref: TM-T21330

  • CSF1R-IN-4
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    CSF1R-IN-4

    CAS:
    <p>CSF1R-IN-4, a potent CSF-1R inhibitor, may impact TAM/glioma cell communication, with cancer research potential. (WO2021197276A1, compound 104)</p>
    Formula:C23H20N6O3
    Color and Shape:Solid
    Molecular weight:428.44

    Ref: TM-T62342

  • c-Fms-IN-10
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    c-Fms-IN-10

    CAS:
    <p>c-Fms-IN-10 is a thieno[3,2-d]pyrimidine derivative, an FMS kinase inhibitor with IC50 of 2 nM, exhibiting anti-tumor properties.</p>
    Formula:C22H19N7OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:429.5

    Ref: TM-T10644

  • CSF1R-IN-13
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    CSF1R-IN-13

    CAS:
    <p>CSF1R-IN-13: potent cancer research CSF1R inhibitor impacting cell growth regulation.</p>
    Formula:C21H20N4O3
    Color and Shape:Solid
    Molecular weight:376.41

    Ref: TM-T61554

  • CSF1R-IN-8
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    CSF1R-IN-8

    CAS:
    <p>CSF1R-IN-8 (Compound 22) is a CSF-1R inhibitor (IC50: 0.012 μM).</p>
    Formula:C24H22N4O4
    Color and Shape:Solid
    Molecular weight:430.46

    Ref: TM-T62390

  • CSF1R-IN-10
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    CSF1R-IN-10

    CAS:
    <p>CSF1R-IN-10 (Compound 48) is a CSF-1R inhibitor (IC50: 0.005 μM).</p>
    Formula:C25H22N4O3
    Color and Shape:Solid
    Molecular weight:426.47

    Ref: TM-T62313

  • Leustroducsin C
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    Leustroducsin C

    CAS:
    <p>Leustroducsin C is an inducer of colony-stimulating factors CSF extracted from Streptomyces platensis SANK 60191.</p>
    Formula:C34H56NO10P
    Color and Shape:Solid
    Molecular weight:669.78

    Ref: TM-T32688

  • CSF1R-IN-14
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    CSF1R-IN-14

    CAS:
    <p>CSF1R-IN-14, an isoindolinone derivative, powerfully inhibits CSF1R, with potential in cancer research. See WO2019134662A1, compound 1.</p>
    Formula:C23H22F3N5O
    Color and Shape:Solid
    Molecular weight:441.45

    Ref: TM-T62557