Tyrosine Kinases
Tyrosine kinase inhibitors are a broad class of compounds that inhibit tyrosine kinases, enzymes responsible for the transfer of a phosphate group to tyrosine residues on proteins, which is a critical step in cell signaling. Dysregulation of tyrosine kinases is implicated in many cancers and other diseases. These inhibitors are essential tools in the study of cell signaling pathways, cancer research, and the development of targeted therapies. At CymitQuimica, we provide a wide range of tyrosine kinase inhibitors to support your research in oncology, cell biology, and therapeutic development.
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BMS-911543
CAS:1271022-90-2
BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, …
Formula:
C23H28N8O
Purity:
97.69% - 99.98%
Color and Shape:
Solid
Molecular weight:
432.52
Ref: TM-T6790
| 1mg | 56.00 € | ||
| 2mg | 78.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 372.00 € | ||
| 50mg | 557.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
RO495
CAS:1258296-60-4
RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested …
Formula:
C17H14Cl2N6O
Purity:
99.4%
Color and Shape:
Solid
Molecular weight:
389.24
Ref: TM-T22416
| 1mg | 61.00 € | ||
| 2mg | 83.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 340.00 € | ||
| 50mg | 499.00 € | ||
| 100mg | 672.00 € | ||
| 200mg | 904.00 € | ||
| 1mL*10mM (DMSO) | 135.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
NVP-BSK805
CAS:1092499-93-8
NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.
Formula:
C27H28F2N6O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
490.55
Ref: TM-T5049
| 1mg | 61.00 € | ||
| 5mg | 129.00 € | ||
| 10mg | 209.00 € | ||
| 25mg | 402.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
JAK-IN-21
CAS:2445499-20-5
JAK-IN-21 is a selective and potent JAK inhibitor that inhibits JAK1, JAK2, J2V617F and TYK2 …
Formula:
C19H16N8O
Purity:
99.75%
Color and Shape:
Liquid
Molecular weight:
372.38
Ref: TM-T61494
| 1mg | 203.00 € | ||
| 2mg | 300.00 € | ||
| 5mg | 507.00 € | ||
| 10mg | 776.00 € | ||
| 25mg | 1,496.00 € | ||
| 50mg | 1,839.00 € | ||
| 100mg | 2,322.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
Tafetinib
CAS:1032265-57-8
Tafetinib (SIM-010603) is a novel potent and orally available tyrosine kinase inhibitor with anti-angiogenic and …
Formula:
C24H29FN4O2
Purity:
96.66%
Color and Shape:
Solid
Molecular weight:
424.51
Ref: TM-T28911
| 1mg | 233.00 € | ||
| 5mg | 581.00 € | ||
| 10mg | 824.00 € | ||
| 25mg | 1,234.00 € | ||
| 50mg | 1,654.00 € | ||
| 100mg | 2,265.00 € | ||
| 500mg | 4,532.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
EGFR-IN-87
CAS:1835666-87-9
EGFR-IN-87 is an EGFR tyrosine kinase inhibitor with potent inhibitory activity, exhibiting IC50 values of …
Formula:
C28H33N7O2
Purity:
98.3%
Color and Shape:
Liquid
Molecular weight:
499.61
Ref: TM-T79888
| 1mg | 182.00 € | ||
| 5mg | 450.00 € | ||
| 10mg | 645.00 € | ||
| 25mg | 1,007.00 € | ||
| 50mg | 1,388.00 € | ||
| 100mg | 1,836.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Brepocitinib
CAS:1883299-62-4
Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits …
Formula:
C18H21F2N7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
389.4
Ref: TM-TQ0010
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 383.00 € | ||
| 100mg | 614.00 € | ||
| 200mg | 859.00 € | ||
| 500mg | 1,270.00 € | ||
| 1mL*10mM (DMSO) | 117.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Zongertinib
CAS:2728667-27-2
Zongertinib is a human HER2-selective tyrosine kinase inhibitor, a novel TK that is highly selective …
Formula:
C29H29N9O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
535.6
Ref: TM-T69534
| 1mg | 143.00 € | ||
| 5mg | 347.00 € | ||
| 10mg | 464.00 € | ||
| 25mg | 696.00 € | ||
| 50mg | 906.00 € | ||
| 100mg | 1,149.00 € | ||
| 200mg | 1,560.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Ropsacitinib
CAS:2127109-84-4
Ropsacitinib (PF-06826647) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain …
Formula:
C20H17N9
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
383.41
Ref: TM-T13237L
| 1mg | 226.00 € | ||
| 2mg | 339.00 € | ||
| 5mg | 481.00 € | ||
| 10mg | 696.00 € | ||
| 25mg | 1,077.00 € | ||
| 50mg | 1,458.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Vecabrutinib
CAS:1510829-06-7
Vecabrutinib (SNS-062) is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and …
Formula:
C22H24ClF4N7O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
529.92
Ref: TM-T17220
| 1mg | 85.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 300.00 € | ||
| 25mg | 487.00 € | ||
| 50mg | 646.00 € | ||
| 100mg | 905.00 € | ||
| 1mL*10mM (DMSO) | 218.00 € |
Estimated delivery in United States, on Monday 17 Mar 2025
Tyk2-IN-3
CAS:1779493-12-7
Tyk2-IN-3 is an inhibitor of Tyk2 pseudokinase (IC50: 485 nM).
Formula:
C25H24N6O3S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
520.63
Ref: TM-T13233
| 25mg | 2,384.00 € | ||
| 50mg | 3,159.00 € | ||
| 100mg | 4,299.00 € |
Estimated delivery in United States, on Monday 17 Mar 2025
