Tyrosine Kinases
Tyrosine kinase inhibitors are a broad class of compounds that inhibit tyrosine kinases, enzymes responsible for the transfer of a phosphate group to tyrosine residues on proteins, which is a critical step in cell signaling. Dysregulation of tyrosine kinases is implicated in many cancers and other diseases. These inhibitors are essential tools in the study of cell signaling pathways, cancer research, and the development of targeted therapies. At CymitQuimica, we provide a wide range of tyrosine kinase inhibitors to support your research in oncology, cell biology, and therapeutic development.
Found 11 products of "Tyrosine Kinases"
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Ilginatinib
CAS:Ilginatinib (NS-018) is a highly active and orally bioavailable inhibitor of JAK2.Formula:C21H20FN7Purity:98.4% - 99.01%Color and Shape:SolidMolecular weight:389.43Ref: TM-T12266
1mg64.00€5mg138.00€10mg187.00€25mg273.00€50mg393.00€100mg562.00€200mg743.00€1mL*10mM (DMSO)133.00€Ilginatinib maleate
CAS:Ilginatinib maleate (NS-018 maleate) is a highly active and orally bioavailable inhibitor of JAK2.
Formula:C25H24FN7O4Purity:99.74% - 99.82%Color and Shape:SolidMolecular weight:505.5SU 4981
CAS:SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity.Formula:C19H18N2O2Purity:95.4%Color and Shape:SoildMolecular weight:306.36Ref: TM-T60094
1mg85.00€5mg170.00€10mg245.00€25mg371.00€50mg522.00€100mg700.00€200mg928.00€1mL*10mM (DMSO)169.00€CZC-8004
CAS:CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Formula:C17H16FN5Purity:99.29%Color and Shape:SolidMolecular weight:309.34BMS-911543
CAS:BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.Formula:C23H28N8OPurity:97.69% - 99.98%Color and Shape:SolidMolecular weight:432.52ZAP-180013
CAS:ZAP-180013 is an inhibitor of zeta-chain-associated protein kinase 70 (ZAP70,IC50 : 1.8 μM).
Formula:C19H17Cl2N3O4SPurity:98.89%Color and Shape:SolidMolecular weight:454.33GSK-2250665A
CAS:GSK-2250665A is an (Itk) inhibitor (pKi 9.2) with selectivity over Aurora B and Btk, inhibiting IFNγ in PBMCs for T-cell signaling studies.Formula:C26H29N5OSPurity:99.38%Color and Shape:SolidMolecular weight:459.61Ropsacitinib
CAS:Ropsacitinib (PF-06826647) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain (IC50: 17 nM).Formula:C20H17N9Purity:99.87%Color and Shape:SolidMolecular weight:383.41ITK inhibitor 2
CAS:ITK inhibitor 2 (compound 4) is a potent and selective ITK inhibitor with an IC50= 2 nM.Formula:C25H33N5O2Purity:99.67%Color and Shape:SolidMolecular weight:435.56TTK inhibitor 3
CAS:TTK inhibitor 3, Selective TTK inhibitor (IC50=3.0 nM), inhibits tumor growth in CAL-51 xenografts and TNBC PDX models.Formula:C42H49N9O3Purity:99.44%Color and Shape:SolidMolecular weight:727.9Vecabrutinib
CAS:Vecabrutinib (SNS-062) is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and 2.2 nM, respectively). Vecabrutinib displays an IC50 of 24 nM for ITK.
Formula:C22H24ClF4N7O2Purity:99.74%Color and Shape:SolidMolecular weight:529.92
