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c-Met/HGFR

c-Met/HGFR

c-Met/HGFR inhibitors target the Hepatocyte Growth Factor Receptor (c-Met), a tyrosine kinase involved in cellular processes such as growth, motility, and morphogenesis. c-Met signaling is implicated in cancer progression, metastasis, and resistance to therapies. Inhibiting c-Met can disrupt tumor growth and spread, making these inhibitors valuable in cancer research. At CymitQuimica, we offer c-Met/HGFR inhibitors to support your research in oncology, metastasis, and targeted cancer therapies.

Found 148 products for "c-Met/HGFR".

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  • Dalmelitinib
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    Dalmelitinib

    CAS:
    Dalmelitinib: oral c-Met kinase inhibitor, IC50 2.9 nM, disrupts MET, AKT, ERK in cancer cells, for NSCLC research.
    Formula:C22H16FN7O2S
    Color and Shape:Solid
    Molecular weight:461.47

    Ref: TM-T62911

  • LCRF-0004
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    LCRF-0004

    CAS:
    LCRF-0004 inhibits RON kinase, key in KRAS-driven pancreatic cancer, reducing cell migration and enhancing chemo sensitivity.
    Formula:C28H18F4N6O2S
    Color and Shape:Solid
    Molecular weight:578.54

    Ref: TM-T71177

  • Mifanertinib dimaleate
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    Mifanertinib dimaleate

    CAS:
    Mifanertinib dimaleate is a potent tyrosine kinase inhibitor with antineoplastic activity .
    Formula:C29H27ClF3N5O10
    Color and Shape:Solid
    Molecular weight:698

    Ref: TM-T72379

  • (R)-Afatinib
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    (R)-Afatinib

    CAS:
    (R)-Afatinib: oral ErbB inhibitor (EGFR/HER2), IC50 ≤14 nM. For ESCC, NSCLC, gastric cancer research.
    Formula:C24H25ClFN5O3
    Color and Shape:Solid
    Molecular weight:485.94

    Ref: TM-T72912

  • MK-8033 hydrochloride
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    MK-8033 hydrochloride

    CAS:
    MK-8033 hydrochloride is an oral ATP-competitive c-Met/Ron inhibitor (IC50: c-Met 1nM, Ron 7nM), used for various cancers including NSCLC.
    Formula:C25H22ClN5O3S
    Color and Shape:Solid
    Molecular weight:507.992

    Ref: TM-T12068

  • Mifanertinib
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    Mifanertinib

    CAS:
    Mifanertinib is a potent tyrosine kinase inhibitor with antineoplastic activity .
    Formula:C21H19ClF3N5O2
    Color and Shape:Solid
    Molecular weight:465.86

    Ref: TM-T70325

  • Glesatinib hydrochloride
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    Glesatinib hydrochloride

    CAS:
    Glesatinib hydrochloride is an orally active and potent dual inhibitor of MET/SMO.
    Formula:C31H28ClF2N5O3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:656.166

    Ref: TM-T15383

  • SAR125844
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    SAR125844

    CAS:
    SAR125844, a potent and highly selective inhibitor of the MET receptor tyrosine kinase (RTK), for intravenous administration. (IC50 value of 4.2 nmol/L)
    Formula:C25H23FN8O2S2
    Purity:98.73%
    Color and Shape:White Solid
    Molecular weight:550.631

    Ref: TM-T5467

  • AC-386
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    AC-386

    CAS:
    AC-386, a potent c-Met inhibitor (IC50 7.42 nM), inhibits cancer cell growth and aids anti-cancer resistance study.
    Formula:C35H34FN5O6
    Color and Shape:Solid
    Molecular weight:639.67

    Ref: TM-T73482

  • c-Met-IN-16
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    c-Met-IN-16

    CAS:
    c-Met-IN-16 is a c-Met inhibitor that can be used for cancer research .
    Formula:C21H17F2N9O
    Color and Shape:Solid
    Molecular weight:449.42

    Ref: TM-T72978

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    Anti-Human MST1R Antibody (MOR07692)

    Anti-MST1R Antibody (MOR07692) is a humanized IgG1 monoclonal antibody specifically targeting MST1R.

    Ref: TM-T9901A-885

  • c-Met-IN-13
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    c-Met-IN-13

    CAS:
    c-Met-IN-13: potent c-Met inhibitor (IC50 2.43 nM), exhibits anti-proliferative, cytotoxic effects; potential cancer therapy.
    Formula:C30H28F2N2O6
    Color and Shape:Solid
    Molecular weight:550.55

    Ref: TM-T63885

  • c-Met-IN-12
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    c-Met-IN-12

    CAS:
    c-Met-IN-12: potent c-Met/AXL/Mer/TYRO3 inhibitor, IC50=10.6 nM, oral, anti-tumor, scaffold for selectivity enhancement.
    Formula:C34H29FN4O4
    Color and Shape:Solid
    Molecular weight:576.62

    Ref: TM-T64080

  • T-1840383
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    T-1840383

    CAS:
    T-1840383 blocks VEGFR-2 and c-Met phosphorylation in endothelial and cancer cells.
    Formula:C30H25ClFN5O4
    Color and Shape:Solid
    Molecular weight:574

    Ref: TM-T28899

  • CymitQuimica logo
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    CE-355621

    CE-355621 is a humanized anti-c-Met IgG1 monoclonal antibody. It effectively binds to human c-Met in A549 cells (KD= 200 pM, IC50= 466 pM) and also binds effectively to c-Met in cynomolgus monkey kidney cells (KD= 610 pM). CE-355621 inhibits the c-Met signaling pathway by blocking HGF binding and significantly suppresses tumor growth dependent on the c-Met/HGF pathway. It is applicable for research in cancers such as glioblastoma and gastric cancer.
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-1782

  • Vabametkib
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    Vabametkib

    CAS:
    Vabametkib: potent HGFR inhibitor, IC50 = 7 nM, halts Hs746T cell growth, used in cancer therapy.
    Formula:C29H34N12O
    Color and Shape:Solid
    Molecular weight:566.66

    Ref: TM-T70434

  • Boditrectinib
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    Boditrectinib

    CAS:
    Boditrectinib: potent TKI, anti-cancer, researches cancer, inflammation, neurodegeneration, infections.
    Formula:C23H24F2N6O
    Color and Shape:Solid
    Molecular weight:438.47

    Ref: TM-T70050

  • c-Met-IN-11
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    c-Met-IN-11

    CAS:
    c-Met-IN-11 is a potent inhibitor of c-MET (IC50: 41.4 nM) and VEGFR-2 (IC50: 71.1 nM).
    Formula:C30H20F2N4O3
    Color and Shape:Solid
    Molecular weight:522.5

    Ref: TM-T63656

  • Axl-IN-8
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    Axl-IN-8

    CAS:
    Axl-IN-8 (NO.1) is a potent inhibitor of AXL (IC50<1 nM) and also inhibits c-MET (IC50: 1-10 nM). : 120.3 nM).
    Formula:C31H29FN6O3
    Color and Shape:Solid
    Molecular weight:552.6

    Ref: TM-T63901

  • Terevalefim
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    Terevalefim

    CAS:
    Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.
    Formula:C9H8N2S
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:176.238

    Ref: TM-T37596