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TAM Receptor

TAM Receptor

TAM receptor inhibitors target the TAM family of receptor tyrosine kinases, which includes Tyro3, Axl, and Mer. These receptors are involved in the regulation of immune responses, cell survival, and clearance of apoptotic cells. Dysregulation of TAM receptors is implicated in cancer, autoimmune diseases, and chronic inflammation. At CymitQuimica, we offer TAM receptor inhibitors to aid your research in immunology, oncology, and inflammation.

Found 32 products of "TAM Receptor"

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  • XL092
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    XL092

    CAS:
    <p>XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.</p>
    Formula:C29H25FN4O5
    Purity:98.60%
    Color and Shape:Solid
    Molecular weight:528.53

    Ref: TM-T9052

  • Cabozantinib
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    Cabozantinib

    CAS:
    <p>Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).</p>
    Formula:C28H24FN3O5
    Purity:99.68% - 99.88%
    Color and Shape:Solid
    Molecular weight:501.51

    Ref: TM-T2586

  • Cabozantinib hydrochloride
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    Cabozantinib hydrochloride

    CAS:
    <p>Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6</p>
    Formula:C28H25ClFN3O5
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:537.96

    Ref: TM-T5164

  • UNC2250
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    UNC2250

    CAS:
    <p>UNC2250 is an effective and specific Mer inhibitor (IC50=1.7 nM).</p>
    Formula:C24H36N6O2
    Purity:98.57% - 99.87%
    Color and Shape:Solid
    Molecular weight:440.58

    Ref: TM-T1968

  • DS-1205
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    DS-1205

    CAS:
    <p>DS-1205: AXL kinase inhibitor (IC50=1.3 nM), also targets MER, MET, TRKA (IC50s: 63, 104, 407 nM), hinders cell migration and tumor growth.</p>
    Formula:C41H42FN5O7
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:735.8

    Ref: TM-T9123

  • Dubermatinib
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    Dubermatinib

    CAS:
    <p>Dubermatinib (TP0903) is a potent and selective Axl kinase inhibitor.</p>
    Formula:C24H30ClN7O2S
    Purity:98.65% - 99.58%
    Color and Shape:Solid
    Molecular weight:516.06

    Ref: TM-T2005

  • RU-302
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    RU-302

    CAS:
    <p>RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain.</p>
    Formula:C24H24F3N3O2S
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:475.53

    Ref: TM-T16806

  • R916562
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    R916562

    CAS:
    <p>R916562 is an orally active and selective Axl/VEGF-R2 inhibitor with IC50s of 136 nM and 24 nM, respectively. R916562 has anti-angiogenesis and anti-metastasis.</p>
    Formula:C26H30ClN9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:536.09

    Ref: TM-T12650

  • AXL-IN-14
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    AXL-IN-14

    CAS:
    <p>AXL-IN-14: orally active, potent AXL inhibitor (IC50=0.8 nM); hinders Gas6/AXL migration, invasion; lowers p-AXL, p-AKT; anti-tumor.</p>
    Formula:C32H24F2N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:566.55

    Ref: TM-T73310

  • AXL-IN-15
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    AXL-IN-15

    CAS:
    <p>AXL-IN-15 (cpd391) is a potent inhibitor of Axl, exhibiting both a dissociation constant (K i) and a half-maximal inhibitory concentration (IC50) of less than 1</p>
    Formula:C26H32F3N9O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:575.59

    Ref: TM-T79045

  • MerTK-IN-1
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    MerTK-IN-1

    CAS:
    <p>MerTK-IN-1 (compound 31) serves as an inhibitor of MerTK, with the capability to bind to the target in vivo.</p>
    Formula:C23H26N8O4
    Color and Shape:Solid
    Molecular weight:478.50

    Ref: TM-T200963

  • MerTK/Axl-IN-1
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    MerTK/Axl-IN-1

    CAS:
    <p>MerTK/Axl-IN-1 (Compound A-910) is a potent and selective dual inhibitor of MerTK/Axl, exhibiting IC50 values of 4.2 nM and 8.8 nM in Ba/F3 cells, and 0.2 nM and 0.9 nM in HTRF cells, respectively. It effectively inhibits pMerTK in vivo and possesses a long half-life and high oral bioavailability.</p>
    Formula:C40H47FN6O4
    Color and Shape:Solid
    Molecular weight:694.84

    Ref: TM-T200517