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PYK2

PYK2

PYK2 inhibitors are compounds that inhibit Proline-Rich Tyrosine Kinase 2 (PYK2), a non-receptor tyrosine kinase involved in cellular processes such as adhesion, migration, and survival. PYK2 is implicated in cancer metastasis and neurological disorders. At CymitQuimica, we offer PYK2 inhibitors to support your research in cancer metastasis, neurobiology, and cell signaling.

Found 7 products of "PYK2"

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  • BT-Amide
    Targetmol
    + Info

    BT-Amide

    BT-Amide is an orally active Pyk2 kinase (Pyk2kinase) inhibitor with an IC50 of 44.69 nM. It prevents glucocorticoid-induced bone loss and demonstrates bone-protective activity in C57BL/6 mice.
    Formula:C29H38ClN7O11P2
    Color and Shape:Solid
    Molecular weight:758.053

    Ref: TM-T204768

    10mg
    To inquire
    50mg
    To inquire
  • PF-562271 besylate
    Targetmol
    + Info

    PF-562271 besylate

    CAS:
    PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.
    Formula:C21H20F3N7O3S·C6H6O3S
    Purity:97.65% - 99.01%
    Color and Shape:Solid
    Molecular weight:665.66

    Ref: TM-T6177

    1mg
    35.00€
    5mg
    74.00€
    10mg
    94.00€
    25mg
    138.00€
    50mg
    198.00€
    100mg
    296.00€
    200mg
    427.00€
    1mL*10mM (DMSO)
    89.00€
  • PF-431396
    Targetmol
    + Info

    PF-431396

    CAS:
    PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).
    Formula:C22H21F3N6O3S
    Purity:98.83% - 99.82%
    Color and Shape:Solid
    Molecular weight:506.5

    Ref: TM-T2314

    5mg
    55.00€
    10mg
    81.00€
    25mg
    145.00€
    50mg
    248.00€
    100mg
    424.00€
    200mg
    627.00€
    1mL*10mM (DMSO)
    65.00€
  • PF-562271 hydrochloride
    Targetmol
    + Info

    PF-562271 hydrochloride

    CAS:
    PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK.
    Formula:C21H20F3N7O3SHCl
    Purity:97.08%
    Color and Shape:Solid
    Molecular weight:543.95

    Ref: TM-T21768

    5mg
    78.00€
    10mg
    97.00€
    25mg
    153.00€
    50mg
    212.00€
    100mg
    314.00€
  • PF-562271
    Targetmol
    + Info

    PF-562271

    CAS:
    PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).
    Formula:C21H20F3N7O3S
    Purity:97.17% - >99.99%
    Color and Shape:Solid
    Molecular weight:507.49

    Ref: TM-T2465

    1mg
    56.00€
    5mg
    120.00€
    10mg
    150.00€
    25mg
    215.00€
    50mg
    358.00€
    100mg
    537.00€
    1mL*10mM (DMSO)
    133.00€
  • NVP-TAE 226
    Targetmol
    + Info

    NVP-TAE 226

    CAS:
    NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.
    Formula:C23H25ClN6O3
    Purity:98.07% - 98.78%
    Color and Shape:Solid
    Molecular weight:468.94

    Ref: TM-T1918

    1mg
    46.00€
    2mg
    59.00€
    5mg
    96.00€
    10mg
    155.00€
    25mg
    250.00€
    50mg
    358.00€
    100mg
    537.00€
    1mL*10mM (DMSO)
    96.00€
  • PF-4618433
    Targetmol
    + Info

    PF-4618433

    CAS:
    PF-4618433 is a selective PYK2 inhibitor with osteogenic activity.
    Formula:C24H27N7O2
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:445.52

    Ref: TM-T22397

    2mg
    77.00€
    5mg
    114.00€
    10mg
    177.00€
    25mg
    371.00€
    50mg
    612.00€
    100mg
    982.00€
    200mg
    1,333.00€
    1mL*10mM (DMSO)
    126.00€