PYK2
PYK2 inhibitors are compounds that inhibit Proline-Rich Tyrosine Kinase 2 (PYK2), a non-receptor tyrosine kinase involved in cellular processes such as adhesion, migration, and survival. PYK2 is implicated in cancer metastasis and neurological disorders. At CymitQuimica, we offer PYK2 inhibitors to support your research in cancer metastasis, neurobiology, and cell signaling.
Found 7 products of "PYK2"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
BT-Amide
<p>BT-Amide is an orally active Pyk2 kinase (Pyk2kinase) inhibitor with an IC50 of 44.69 nM. It prevents glucocorticoid-induced bone loss and demonstrates bone-protective activity in C57BL/6 mice.</p>Formula:C29H38ClN7O11P2Color and Shape:SolidMolecular weight:758.053PF-562271 besylate
CAS:<p>PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.</p>Formula:C21H20F3N7O3S·C6H6O3SPurity:97.65% - 99.01%Color and Shape:SolidMolecular weight:665.66PF-431396
CAS:<p>PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).</p>Formula:C22H21F3N6O3SPurity:98.83% - 99.82%Color and Shape:SolidMolecular weight:506.5PF-562271 hydrochloride
CAS:<p>PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK.</p>Formula:C21H20F3N7O3SHClPurity:97.08%Color and Shape:SolidMolecular weight:543.95PF-562271
CAS:<p>PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).</p>Formula:C21H20F3N7O3SPurity:97.17% - >99.99%Color and Shape:SolidMolecular weight:507.49NVP-TAE 226
CAS:<p>NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.</p>Formula:C23H25ClN6O3Purity:98.07% - 98.78%Color and Shape:SolidMolecular weight:468.94PF-4618433
CAS:<p>PF-4618433 is a selective PYK2 inhibitor with osteogenic activity.</p>Formula:C24H27N7O2Purity:99.95%Color and Shape:SolidMolecular weight:445.52
