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Opioid Receptor

Opioid Receptor

Opioid receptors are a group of G protein-coupled receptors that mediate the effects of endogenous and exogenous opioids. These receptors play a central role in pain modulation, mood regulation, and addictive behaviors. Opioid receptor agonists and antagonists are extensively used in pain management and addiction treatment, as well as in research on neurological and psychiatric disorders. At CymitQuimica, we provide a comprehensive selection of high-quality opioid receptor modulators to support your research in neurobiology, pain management, and addiction therapy.

Found 296 products of "Opioid Receptor"

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  • CymitQuimica logo
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    KOR agonist 5

    <p>KOR agonist 5 (Compound 10a) is both a KOR/MOR modulator, exhibiting agonistic effects on KOR and antagonistic effects on MOR. It effectively blocks morphine-induced antinociception and gastrointestinal motility inhibition. KOR agonist 5 is applicable in research related to substance use disorder (SUD).</p>
    Formula:C38H38N2O5
    Color and Shape:Solid
    Molecular weight:602.72

    Ref: TM-T205351

  • [DAla2, DArg6] Dynorphin A, (1-13) (porcine)
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    [DAla2, DArg6] Dynorphin A, (1-13) (porcine)

    CAS:
    <p>'[DAla2, DArg6] Dynorphin A (1-13) porcine is a potent opioid peptide resistant to enzymatic degradation.'</p>
    Formula:C76H128N24O15
    Color and Shape:Solid
    Molecular weight:1617.98

    Ref: TM-T76337

  • Naldemedine
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    Naldemedine

    CAS:
    <p>Naldemedine (S 297995), developed by Shionogi, is a drug for opioid side effects like constipation. It's well tolerated with minor GI issues.</p>
    Formula:C32H34N4O6
    Color and Shape:Solid
    Molecular weight:570.64

    Ref: TM-T33583

  • AH 8532
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    AH 8532

    CAS:
    <p>AH 8532 is an opioid compound with analgesic effects and is effective in inhibiting the quinone-induced writhing response in mice, with an oral ED50 of 16 mg/kg.</p>
    Formula:C16H23ClN2O
    Color and Shape:Solid
    Molecular weight:294.82

    Ref: TM-T203113

  • Piperidylthiambutene hydrochloride
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    Piperidylthiambutene hydrochloride

    CAS:
    <p>Piperidylthiambutene hydrochloride is an opioid compound that exhibits analgesic effects in animal models.</p>
    Formula:C17H22ClNS2
    Color and Shape:Solid
    Molecular weight:339.95

    Ref: TM-T203228

  • (-)-9-Hydroxycorynantheidine
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    (-)-9-Hydroxycorynantheidine

    CAS:
    <p>(-)-9-Hydroxycorynantheidine (9-O-Desmethyl mitragynine) is a demethylated analog of Mitragynine, functioning as a selective and partial agonist for the μ-opioid receptor (μ-opioid receptor). This compound inhibits electrically stimulated twitch contractions in the guinea pig ileum.</p>
    Formula:C22H28N2O4
    Color and Shape:Solid
    Molecular weight:384.47

    Ref: TM-T203596

  • MT-7716 hydrochloride
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    MT-7716 hydrochloride

    CAS:
    <p>MT-7716 hydrochloride is a selective agonist of non-peptide nociceptin receptor (NOP)</p>
    Formula:C27H29ClN4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:477

    Ref: TM-T12120

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    HINT1-IN-1

    <p>HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).</p>
    Formula:C23H24N8O5
    Color and Shape:Solid
    Molecular weight:492.49

    Ref: TM-T205282

  • [Arg14,Lys15]Nociceptin
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    [Arg14,Lys15]Nociceptin

    CAS:
    <p>Potent NOP agonist (EC50 = 1 nM), &gt;875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.</p>
    Formula:C82H137N31O22
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1909.18

    Ref: TM-TP1986

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    KOR agonist 4

    <p>KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.</p>
    Formula:C21H25N3
    Color and Shape:Solid
    Molecular weight:319.44

    Ref: TM-T205240

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    β-Endorphin, equine TFA

    <p>β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3</p>
    Formula:C156H249F3N42O46S
    Color and Shape:Solid
    Molecular weight:3537.96

    Ref: TM-T76027

  • N-Desmethyl Loperamide
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    N-Desmethyl Loperamide

    CAS:
    <p>N-Desmethyl Loperamide is the major metabolite of loperamide. It is also used as the precusor for radiolabelled loperamide.</p>
    Formula:C28H31ClN2O2
    Color and Shape:Solid
    Molecular weight:463.01

    Ref: TM-T33615

  • β-Endorphin, equine
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    β-Endorphin, equine

    CAS:
    <p>Endorphin Beta is A substance produced in the brain, especially in the pituitary gland, Endorphin Beta blocks the sensation of pain.</p>
    Formula:C154H248N42O44S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3423.94

    Ref: TM-TP1647

  • Akuammicine
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    Akuammicine

    CAS:
    <p>Akuammicine, as an indole alkaloid from Catharanthus roseus, can be used in cancer cell eradication.</p>
    Formula:C20H22N2O2
    Color and Shape:Solid
    Molecular weight:322.408

    Ref: TM-T29805

  • Porcine dynorphin A(1-13)
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    Porcine dynorphin A(1-13)

    CAS:
    <p>Porcine dynorphin A (1-13) is a potent κ opioid receptor agonist; it's antinociceptive and raises [Ca2+]i in neurons like NMDA.</p>
    Formula:C75H126N24O15
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1603.95

    Ref: TM-TP1179

  • Loperamide phenyl
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    Loperamide phenyl

    CAS:
    <p>Loperamide phenyl, an impurity detected in Loperamide, is an opioid receptor agonist.</p>
    Formula:C35H37ClN2O2
    Color and Shape:Solid
    Molecular weight:553.14

    Ref: TM-T38809

  • Alvimopan dihydrate (LY246736 dihydrate)
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    Alvimopan dihydrate (LY246736 dihydrate)

    CAS:
    <p>Alvimopan dihydrate is a potent, oral μ-opioid receptor blocker (IC50 1.7 nM, Ki 0.47 nM) used in postoperative ileus research.</p>
    Formula:C25H36N2O6
    Color and Shape:Solid
    Molecular weight:460.56

    Ref: TM-T22238

  • Endomorphin 2 TFA
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    Endomorphin 2 TFA

    CAS:
    <p>Endomorphin 2 TFA, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.</p>
    Formula:C34H38F3N5O7
    Color and Shape:Solid
    Molecular weight:685.69

    Ref: TM-T11198

  • BMS-986121
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    BMS-986121

    CAS:
    <p>BMS-986121 is a selective positive allosteric modulator (PAM) of the μ opioid receptor with analgesic effects.</p>
    Formula:C15H9Cl2N3O2S
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:366.22

    Ref: TM-T40392

  • Asimadoline
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    Asimadoline

    CAS:
    <p>Asimadoline (EMD-61753) is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany.</p>
    Formula:C27H30N2O2
    Color and Shape:Solid
    Molecular weight:414.54

    Ref: TM-T4633