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DNA/RNA Synthesis

DNA/RNA Synthesis

Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.

Found 799 products of "DNA/RNA Synthesis"

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  • Gossypolone

    CAS:
    Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.
    Formula:C30H26O10
    Purity:99.15%
    Color and Shape:Solid
    Molecular weight:546.52

    Ref: TM-T31987

    1mg
    185.00€
    5mg
    426.00€
    10mg
    627.00€
    25mg
    938.00€
    50mg
    1,320.00€
    100mg
    1,786.00€
    500mg
    3,591.00€
    1mL*10mM (DMSO)
    535.00€
  • Thymectacin

    CAS:
    Thymectacin (NB 1011) is a selective thymidine synthase (TS) inhibitor with anticancer activity for the study of colon cancer and solid tumors.
    Formula:C21H25BrN3O9P
    Purity:97.05% - 99.49%
    Color and Shape:Solid
    Molecular weight:574.32

    Ref: TM-T24881

    1mg
    110.00€
    5mg
    264.00€
    10mg
    427.00€
    25mg
    858.00€
    50mg
    1,378.00€
    100mg
    1,783.00€
  • LNA-Adenosine

    CAS:
    LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.
    Formula:C11H13N5O4
    Purity:99.15%
    Color and Shape:Solid
    Molecular weight:279.25

    Ref: TM-T32826

    5mg
    34.00€
    50mg
    To inquire
  • CeMMEC1

    CAS:
    CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).
    Formula:C19H16N2O4
    Purity:98.9% - 99.92%
    Color and Shape:Solid
    Molecular weight:336.34

    Ref: TM-T4345

    10mg
    35.00€
    25mg
    70.00€
    50mg
    114.00€
    100mg
    168.00€
  • Sorivudine

    CAS:
    Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.
    Formula:C11H13BrN2O6
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:349.13

    Ref: TM-T16911

    1mg
    56.00€
    5mg
    120.00€
    10mg
    172.00€
    25mg
    296.00€
    50mg
    439.00€
  • Lomibuvir

    CAS:
    Lomibuvir (VCH-222, VX-222) is an allosteric inhibitor of HCV NS5B with Kd 17 nM, blocks RNA elongation, EC50 5.2 nM for 1b/Con1.
    Formula:C25H35NO4S
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:445.61

    Ref: TM-T6729

    1mg
    42.00€
    5mg
    88.00€
    10mg
    130.00€
    25mg
    241.00€
    50mg
    385.00€
    1mL*10mM (DMSO)
    87.00€
  • Xanthosine-5'-Triphosphate trisodium

    CAS:
    Xanthosine-5'-Triphosphate (5'-XTP) trisodium is a nucleotide formed through the deamination of purine bases. It serves as a substrate for inosine triphosphate pyrophosphatase (ITPase).
    Formula:C10H12N4Na3O15P3
    Color and Shape:Solid
    Molecular weight:590.111

    Ref: TM-TXB-00592

    10mg
    To inquire
    50mg
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  • D-G23

    CAS:
    D-G23 is a selective RAD52 inhibitor. It disrupts RAD52-mediated DNA repair pathways and suppresses the growth of cancer cells deficient in BRCA1 and BRCA2. D-G23 shows promise for research into homologous recombination-related cancers caused by BRCA1/2 mutations, such as hereditary breast and ovarian cancers.
    Formula:C19H22N4O3
    Color and Shape:Solid
    Molecular weight:354.403

    Ref: TM-T206763

    10mg
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    50mg
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  • Antitumor agent-75


    Antitumor agent-75 is a novel and potent antitumor agent.
    Formula:C26H23FN6
    Color and Shape:Solid
    Molecular weight:438.5

    Ref: TM-T62510

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • RAD51-IN-8


    RAD51-IN-8 inhibits RAD51-BRCA2 interaction and H4A4 with EC50 of 19 μM; a micromolar PPI inhibitor.
    Formula:C16H14Cl2FN3O2
    Color and Shape:Solid
    Molecular weight:370.21

    Ref: TM-T61469

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • Plevitrexed

    CAS:
    Plevitrexed, an oral TS inhibitor (Ki: 0.44 nM), targets α-folate receptor & reduced folate carrier, treats gastric cancer.
    Formula:C26H25FN8O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:532.53

    Ref: TM-T12635L

    25mg
    2,448.00€
    50mg
    3,222.00€
    100mg
    4,410.00€
  • CB 30900

    CAS:
    CB30900 is a novel and effective thymidylate synthase inhibitor.
    Formula:C31H32FN5O9
    Color and Shape:Solid
    Molecular weight:637.61

    Ref: TM-T30760

    25mg
    2,313.00€
    50mg
    3,042.00€
    100mg
    4,140.00€
  • 6-N-Hydroxylaminopurine

    CAS:
    6-N-Hydroxylaminopurine is a base analog with mutagenic activity.
    Formula:C5H5N5O
    Molecular weight:151.13

    Ref: TM-T210412

    10mg
    To inquire
    50mg
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  • RNase L ligand 3

    CAS:
    RNase L ligand 3 is an RNase L ligand employed in the synthesis of F3-PEG8-RiboTAC.
    Formula:C27H27N3OS
    Color and Shape:Solid
    Molecular weight:441.59

    Ref: TM-T210787

    10mg
    To inquire
    50mg
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  • DHX9-IN-19

    CAS:
    DHX9-IN-19 (compound 3) is an orally active inhibitor of DHX9, playing a significant role in cancer research.
    Formula:C20H21ClN4O4S2
    Color and Shape:Solid
    Molecular weight:480.988

    Ref: TM-T204732

    10mg
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    50mg
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  • Tetrahydrouridine dihydrate


    THU dihydrate, a potent CDA inhibitor, outperforms cytidine by blocking the enzyme's active site.
    Formula:C9H20N2O8
    Color and Shape:Solid
    Molecular weight:284.26

    Ref: TM-T60553

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Adafosbuvir

    CAS:
    Adafosbuvir has antiviral activity.
    Formula:C22H29FN3O10P
    Color and Shape:Solid
    Molecular weight:545.457

    Ref: TM-T26560

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • ART615


    ART615 is a related isomer of ART558. ART615 inhibits Polθ by <10% at 12 μM and is able to act as a control for ART558 (IC50:7.9 nM).
    Formula:C21H21F3N4O2
    Color and Shape:Solid
    Molecular weight:418.41

    Ref: TM-T62186

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • Epolactaene

    CAS:
    Epolactaene: neuritogenic, inhibits mammalian DNA polymerases & human DNA topoisomerase II.
    Formula:C21H27NO6
    Color and Shape:Solid
    Molecular weight:389.44

    Ref: TM-T70284

    25mg
    2,718.00€
    50mg
    3,582.00€
    100mg
    4,950.00€
  • Homer

    CAS:
    Homer is a probe designed to target WD repeat domain 5 (WDR5). In MV4-11 cells, Homer induces the degradation of WDR5 with a half-maximal degradation concentration (DC50) of 53 nM. At a concentration of 1 µM, Homer decreases the protein levels of WDR5 in MV4-11 cells without affecting the mRNA levels that encode WDR5.
    Formula:C52H60F3N9O7S
    Color and Shape:Solid
    Molecular weight:1012.15

    Ref: TM-T201354

    25mg
    1,690.00€
    50mg
    2,210.00€
    100mg
    2,879.00€
  • 3′-Amino-2′,3′-dideoxy-CTP

    CAS:
    3′-Amino-2′,3′-dideoxy-CTP is an analog of nucleoside triphosphates. It selectively inhibits DNA polymerase β.
    Formula:C9H17N4O12P3
    Color and Shape:Solid
    Molecular weight:466.17

    Ref: TM-TSW-01126

    10mg
    To inquire
    50mg
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  • L-Tyrosyl-L-glutamic acid

    CAS:
    L-Tyrosyl-L-glutamic acid acts as an inhibitor of the amino acid permease GAP1.
    Formula:C14H18N2O6
    Color and Shape:Solid
    Molecular weight:310.3

    Ref: TM-T201575

    10mg
    To inquire
    50mg
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  • Bersiporocin

    CAS:

    Bersiporocin is a novel prolyl-tRNA synthetase (PRS) inhibitor that exerts antifibrotic effects through downregulation of collagen synthesis in IPF.

    Formula:C15H19Cl2N3O
    Purity:98.88% - 99.79%
    Color and Shape:Solid
    Molecular weight:328.24

    Ref: TM-T39739

    1mg
    452.00€
    5mg
    1,359.00€
    10mg
    2,262.00€
  • (Rac)-Plevitrexed

    CAS:
    (Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).
    Formula:C26H25FN8O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:532.53

    Ref: TM-T12674

    25mg
    2,988.00€
    50mg
    3,943.00€
    100mg
    5,490.00€
  • 3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite

    CAS:
    3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite serves as a precursor of adenosine nucleotide monomers used in the solid-phase synthesis of oligonucleotides, particularly for modifying oligonucleotides such as terminally modified DNA strands. It features Trityl (Tr), Cyanoethyl (CE), and Dimethylformamidine (DMF) protective groups, classifying it as a ddNTP adenosine nucleoside suitable for applications like oligonucleotide solid-phase synthesis, probe design, and chain termination sequencing.
    Formula:C41H50N9O3P
    Color and Shape:Solid
    Molecular weight:747.87

    Ref: TM-TSW-01106

    10mg
    To inquire
    50mg
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  • ATIC-IN-2

    CAS:
    ATIC-IN-2 (Compound 1) is a competitive inhibitor of the bifunctional enzyme AICAR Tfase/IMPCH (ATIC), binding to inosine monophosphate cyclohydrolase (IMPCH) with a Ki of 0.13 μM.
    Formula:C4H4N4O3S
    Color and Shape:Solid
    Molecular weight:188.165

    Ref: TM-T204433

    10mg
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    50mg
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  • GHP-88309

    CAS:
    GHP-88309 is an orally active, broad-spectrum anti-paramyxovirus agent that targets viral polymerase, interrupting viral RNA synthesis. It effectively inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with an EC50 of 0.06-1.2 μM. In mouse models, GHP-88309 demonstrates significant anti-infective activity.
    Formula:C16H11FN2O
    Color and Shape:Solid
    Molecular weight:266.27

    Ref: TM-T204819

    10mg
    To inquire
    50mg
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  • 5-Fluorouridine 5'-phosphate

    CAS:
    5-Fluorouridine 5'-phosphate acts as an ODCase (uridine 5'-monophosphate decarboxylase) inhibitor, exhibiting a Ki value of 98 µM for human ODCase and 645 µM for Methanococcus jannaschii ODCase. This compound also shows inhibitory activity on leukemia and lymphoma cell lines, making it useful for cancer research studies.
    Formula:C9H12FN2O9P
    Color and Shape:Solid
    Molecular weight:342.172

    Ref: TM-T205644

    10mg
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    50mg
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  • UMPK ligand 1

    CAS:

    UMPK ligand 1 (ZINC07785412) serves as a ligand for uridine monophosphate kinase (UMPK).

    Formula:C15H22N4O5S
    Color and Shape:Solid
    Molecular weight:370.424

    Ref: TM-T204579

    10mg
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    50mg
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  • WRN inhibitor 11

    CAS:
    WRN inhibitor 11 (Example 17) is an orally effective inhibitor of WRN helicase, with an IC50 of 63 nM.
    Formula:C34H35ClF3N9O5
    Color and Shape:Solid
    Molecular weight:742.15

    Ref: TM-T201262

    25mg
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    50mg
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    100mg
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  • Polθ-IN-6

    CAS:
    Polθ-IN-6 (Compound 89) is an inhibitor of DNA polymerase theta (Polθ) and exhibits antitumor activity.
    Formula:C25H23N3O3S
    Color and Shape:Solid
    Molecular weight:445.53

    Ref: TM-T200918

    25mg
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    50mg
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    100mg
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  • WRN inhibitor 12

    CAS:
    WRN inhibitor 12 (compound 5) serves as an inhibitor for the WRN helicase.
    Formula:C33H33ClF3N9O5
    Color and Shape:Solid
    Molecular weight:728.12

    Ref: TM-T201316

    25mg
    To inquire
    50mg
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    100mg
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  • Polθ-IN-5

    CAS:
    Polθ-IN-5 (Compound 139) is an inhibitor of DNA polymerase theta (Polθ) that exhibits antitumor activity.
    Formula:C23H18ClF2N7O3S
    Color and Shape:Solid
    Molecular weight:545.95

    Ref: TM-T200913

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • (R)-CSN5i-3

    CAS:
    (R)-CSN5i-3 is CSN5i-3 of the R configuration.
    Formula:C28H29F2N5O2
    Purity:99.76% - 99.97%
    Color and Shape:Solid
    Molecular weight:505.56

    Ref: TM-T12620

    1mg
    148.00€
    5mg
    334.00€
    10mg
    465.00€
    25mg
    800.00€
  • 12(S)-HETE

    CAS:

    Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.

    Formula:C20H32O3
    Color and Shape:Solid
    Molecular weight:320.47

    Ref: TM-T37047

    100μg (312.04μM*1mL in Ethanol)
    1,758.00€
  • APE1-IN-3

    CAS:
    APE1-IN-3 (Compound 1), an APE1 inhibitor, is utilized in cancer research.
    Formula:C17H16O4
    Color and Shape:Solid
    Molecular weight:284.31

    Ref: TM-T89919

    10mg
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    50mg
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  • 5-Methylcytosine hydrochloride

    CAS:
    5-Methylcytosine hydrochloride plays a critical role in regulating gene expression, promoting genomic imprinting, and inhibiting transposon factors. It is also closely associated with translation fidelity and tRNA recognition.
    Formula:C5H8ClN3O
    Color and Shape:Solid
    Molecular weight:161.59

    Ref: TM-T201054

    10mg
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    50mg
    To inquire
  • GSK_WRN4

    CAS:
    GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer research
    Formula:C16H20N2O4S
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:336.41

    Ref: TM-T200332

    1mg
    905.00€
    5mg
    1,691.00€
    10mg
    2,262.00€
    25mg
    3,392.00€
    50mg
    4,550.00€
  • GTSE1-IN-1

    CAS:
    GTSE1-IN-1 (compound Y18), an orally active GTSE1 inhibitor, exhibits notable anticancer properties. It effectively represses the proliferation of cancer cells by downregulating GTSE1 transcription and expression, which leads to DNA damage and promotes persistent cell cycle arrest and cellular senescence. Moreover, GTSE1-IN-1 substantially reduces the adhesion, migration, and invasion of colorectal cancer HCT116 cells and non-small cell lung cancer A549 cells in vitro.
    Formula:C21H24FN7
    Color and Shape:Solid
    Molecular weight:393.46

    Ref: TM-T200127

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • MTH1 activator-1

    CAS:
    MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.
    Formula:C29H23F3N4O2
    Color and Shape:Solid
    Molecular weight:516.514

    Ref: TM-T204503

    10mg
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    50mg
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  • AB25583

    CAS:
    AB25583 is a small molecule inhibitor of Polθ helicase (Polθ-hel) with an IC50 of 6 nM. It selectively kills cells deficient in BRCA1/2 and synergizes with Olaparib in cancer cells harboring pathogenic BRCA1/2 mutations. AB25583 can be utilized in tumor research.
    Formula:C22H17ClN4O3S
    Color and Shape:Solid
    Molecular weight:452.91

    Ref: TM-T200101

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • T-2513 hydrochloride

    CAS:
    T-2513 hydrochloride: selective topoisomerase I inhibitor, binds DNA complex, halts DNA/RNA synthesis, causes cell death.
    Formula:C25H28ClN3O5
    Color and Shape:Solid
    Molecular weight:485.96

    Ref: TM-T63225

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • KL-50

    CAS:
    KL-50, a selective toxin, effectively targets tumors deficient in the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which corrects O6-alkylguanine lesions. This compound induces both DNA damage response pathways and cell cycle arrest in MGMT-deficient cells, regardless of mismatch repair (MMR) status. KL-50 shows promise in the study of brain tumors lacking MGMT.
    Formula:C7H7FN6O2
    Color and Shape:Solid
    Molecular weight:226.17

    Ref: TM-T200136

    25mg
    1,784.00€
    50mg
    2,333.00€
    100mg
    3,039.00€
  • And1 degrader 1

    CAS:
    And1 degrader 1 (Compound A15) is a degrader of acidic nucleoplasmic DNA-binding protein 1 (And1) that notably induces degradation of And1 in NSCLC cells. When combined with Olaparib (1 μM), And1 degrader 1 at a concentration of 5 μM effectively inhibits proliferation in A549 and H460 cells. This compound is applicable in cancer research studies.
    Formula:C26H27Cl2N3O
    Color and Shape:Solid
    Molecular weight:468.42

    Ref: TM-T200443

    25mg
    1,458.00€
    50mg
    1,839.00€
    100mg
    2,322.00€
  • RAD51-IN-7

    CAS:
    RAD51-IN-7 inhibits RAD51 gene, with potential for mitochondrial disorders. (From WO2021164746A1, cmpd 71)
    Formula:C25H31N5O4S2
    Color and Shape:Solid
    Molecular weight:529.67

    Ref: TM-T63728

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • RAD51-IN-5

    CAS:
    RAD51-IN-5 blocks RAD51; may aid mitochondrial disorder research. (WO2021164746A1, cmpd 3)
    Formula:C26H38N4O5S2
    Color and Shape:Solid
    Molecular weight:550.73

    Ref: TM-T63892

    25mg
    1,791.00€
    50mg
    2,872.00€
  • NRTT-IN-1

    CAS:
    NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.
    Formula:C28H24FN5O5
    Color and Shape:Solid
    Molecular weight:529.519

    Ref: TM-T205482

    10mg
    To inquire
    50mg
    To inquire
  • LN-439A

    CAS:
    LN-439A (compound LN-439A) is a novel BAP1 inhibitor that suppresses the growth of basal-like breast cancer by degrading KLF5.
    Formula:C24H26FN3O4
    Color and Shape:Solid
    Molecular weight:439.48

    Ref: TM-T200435

    25mg
    1,586.00€
    50mg
    2,072.00€
    100mg
    2,660.00€
  • PolQi1

    CAS:
    PolQi1 is a highly efficient and selective Polϴ (DNA polymerase theta) inhibitor with an IC50 of 2 nM, showing potential for cancer therapy.
    Formula:C18H14ClF5N4O2
    Purity:98.97%
    Color and Shape:Solid
    Molecular weight:448.77

    Ref: TM-T89335

    1mg
    175.00€
    5mg
    434.00€
    10mg
    622.00€
    25mg
    973.00€
    50mg
    1,341.00€
    100mg
    1,773.00€
    200mg
    2,422.00€
  • TREX1-IN-4

    CAS:
    TREX1-IN-4 (Compound 96) is an inhibitor of TREX1 and TREX2, exhibiting an IC50 of less than 0.1 μM for TREX1 and an IC50 of less than 1 μM for TREX2. It has an EC50 ranging from 0.1 to 10 μM in HCT116 cells. TREX1-IN-4 is applicable for research in the field of cancer.
    Formula:C24H19ClN6O4
    Color and Shape:Solid
    Molecular weight:490.898

    Ref: TM-T205208

    10mg
    To inquire
    50mg
    To inquire
  • HPH-15

    CAS:
    HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.
    Formula:C19H31N3S4
    Color and Shape:Solid
    Molecular weight:429.73

    Ref: TM-T205327

    10mg
    To inquire
    50mg
    To inquire
  • TREX1-IN-3

    CAS:
    TREX1-IN-3 (Compound 95) is an inhibitor of TREX1 and TREX2, with an IC50 of less than 0.1 μM for TREX1 and less than 1 μM for TREX2, as well as an EC50 of less than 1 μM for HCT116 cells. It is applicable for research in the field of cancer.
    Formula:C24H19ClN6O4
    Color and Shape:Solid
    Molecular weight:490.898

    Ref: TM-T205254

    10mg
    To inquire
    50mg
    To inquire
  • KWR095

    CAS:
    KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.
    Formula:C33H31ClF3N9O4
    Color and Shape:Solid
    Molecular weight:710.105

    Ref: TM-T205595

    10mg
    To inquire
    50mg
    To inquire
  • EFdA-TP tetrasodium

    CAS:
    EFdA-TP tetrasodium is a potent HIV-1 inhibitor that blocks DNA synthesis as an ICT or DCT.
    Formula:C12H11FN5Na4O12P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:621.12

    Ref: TM-T72461

    25mg
    2,157.00€
    50mg
    2,832.00€
    100mg
    3,800.00€
  • 5-Iminodaunorubicin hydrochloride

    CAS:
    5-Iminodaunorubicin HCl: quinone-modified anthracycline with antitumor properties, induces DNA breaks in cancer cells.
    Formula:C27H31ClN2O9
    Color and Shape:Solid
    Molecular weight:563.00

    Ref: TM-T72115

    25mg
    1,026.00€
    50mg
    1,339.00€
    100mg
    2,023.00€
  • Werner syndrome RecQ helicase-IN-2

    CAS:
    Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase (WRN) inhibitor, useful in research on colorectal and gastric cancers.
    Formula:C32H34F3N9O5
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:681.67

    Ref: TM-T72108

    1mg
    130.00€
    5mg
    313.00€
    10mg
    557.00€
    25mg
    1,224.00€
    50mg
    2,088.00€
  • GR 122222X

    CAS:
    GR 122222X is an inhibitor of topoisomerase II.
    Formula:C26H35N5O11S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:625.65

    Ref: TM-T24100

    25mg
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    50mg
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    100mg
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  • NSC 641396

    CAS:
    NSC 641396 is a ribonucleotide reductase (RNR) inhibitor with an IC50 value of 1.2 μM. Additionally, it acts as an inhibitor of protein arginine N-methyltransferase 9 (PRMT9) and exhibits antitumor properties.
    Formula:C18H13NO3
    Color and Shape:Solid
    Molecular weight:291.301

    Ref: TM-T204449

    10mg
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    50mg
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  • Metesind Glucuronate

    CAS:
    Metesind Glucuronate is an antineoplastic. It also is a specific thymidylate synthase inhibitor.
    Formula:C29H34N4O10S
    Color and Shape:Solid
    Molecular weight:630.67

    Ref: TM-T24454

    5mg
    1,064.00€
    10mg
    1,605.00€
    25mg
    2,727.00€
    50mg
    To inquire
  • DHX9-IN-9

    CAS:
    DHX9-IN-9 (509) acts as an inhibitor of the RNA helicase DHX9, demonstrating an EC50 of 0.0177 μM in DHX9 cellular target engagement, primarily utilized in cancer research [1].
    Formula:C21H21ClFN5O3S2
    Color and Shape:Solid
    Molecular weight:510

    Ref: TM-T86205

    10mg
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    50mg
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  • WRN inhibitor 13

    CAS:
    WRN inhibitor 13 is an inhibitor of the WRN helicase with a pIC50 value ranging from 6 to 7.
    Formula:C16H20N2O5S
    Color and Shape:Solid
    Molecular weight:352.405

    Ref: TM-T204389

    10mg
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    50mg
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  • DNA polymerase-IN-6

    CAS:
    DNA polymerase-IN-6 (Compound 27) exhibits inhibitory activity against DNA polymerase, with EC50 values of 0.33 µM for HCMV, 1.9 µM for HSV-1, 0.76 µM for HSV-2, and 0.066 µM for EBV.
    Formula:C26H28ClFN8O4
    Color and Shape:Solid
    Molecular weight:571.003

    Ref: TM-T204284

    10mg
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    50mg
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  • Uridine 3',5'-diphosphate

    CAS:
    Uridine 3′,5′-diphosphate (3′,5′-UDP; Compound pUp) serves as a competitive RNase inhibitor [1].
    Formula:C9H14N2O12P2
    Color and Shape:Solid
    Molecular weight:404.16

    Ref: TM-T87599

    10mg
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    50mg
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  • WRN inhibitor 7

    CAS:

    WRN inhibitor 7 (Compound h6), a potent inhibitor of Werner syndrome helicase, demonstrates effective suppression of WRN's helicase and ATPase activities with IC50 values of 9.8 μM and 15.8 μM, respectively. This compound is utilized in the study of microsatellite instable (MSI) cancers [1].

    Formula:C27H23N3O6
    Color and Shape:Solid
    Molecular weight:485.49

    Ref: TM-T87635

    10mg
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    50mg
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  • 2,5-Di-tert-butyl-1,4-benzoquinone

    CAS:
    2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent found primarily in marine Streptomyces sp. VITVSK1, effective against emerging antibiotic resistance. Additionally, it serves as a powerful inhibitor of RNA polymerase.
    Formula:C14H20O2
    Color and Shape:Solid
    Molecular weight:220.31

    Ref: TM-T201504

    10mg
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    50mg
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  • iPAF1C

    CAS:

    iPAF1C is a powerful inhibitor of the polymerase-associated factor 1 complex (PAF1C) and exhibits anti-HIV activity [1].

    Formula:C27H26BrFN4O
    Color and Shape:Solid
    Molecular weight:521.42

    Ref: TM-T86731

    10mg
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    50mg
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  • CYP2C19-IN-1


    CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.
    Formula:C26H26N2O6S
    Color and Shape:Solid
    Molecular weight:494.56

    Ref: TM-T63337

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • Methyl 3-oxodecanoate

    CAS:

    Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.

    Formula:C11H20O3
    Color and Shape:Solid
    Molecular weight:200.275

    Ref: TM-T206384

    10mg
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    50mg
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  • RAD51-IN-6

    CAS:
    RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)
    Formula:C27H40N3O5PS
    Color and Shape:Solid
    Molecular weight:549.66

    Ref: TM-T63883

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • DIDS

    CAS:
    DIDS inhibits anion exchangers reversibly then irreversibly and blocks RAD51.
    Formula:C16H10N2O6S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:454.52

    Ref: TM-T20694

    25mg
    1,730.00€
    50mg
    2,262.00€
    100mg
    2,945.00€
  • DENV-IN-6

    CAS:
    DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.
    Formula:C23H26ClFN4OS
    Color and Shape:Solid
    Molecular weight:461

    Ref: TM-T62908

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • Deoxythymidine-5'-triphosphate-d15

    CAS:
    Deoxythymidine-5'-triphosphate-d15 (dTTP-d15) dilithium is a deuterium-labeled form of deoxythymidine-5'-triphosphate. Deoxythymidine-5'-triphosphate (dTTP) is a triphosphate nucleotide utilized in DNA synthesis.
    Formula:C10H15Li2N2O14P3
    Color and Shape:Solid
    Molecular weight:509.13

    Ref: TM-T211806

    10mg
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    50mg
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  • Pol I-IN-1


    Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition
    Formula:C23H22N4O2
    Color and Shape:Solid
    Molecular weight:386.45

    Ref: TM-T61720

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • L-2'-Fd4C

    CAS:
    L-2'-Fd4C is an L-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity [1].
    Formula:C9H10FN3O3
    Color and Shape:Solid
    Molecular weight:227.19

    Ref: TM-T60285

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • Dencatistat

    CAS:
    Dencatistat is a highly selective and oral cytidine triphosphate synthase 1 CTPS1 inhibitor specific.CTPS1-IN-2 for B-cell, T-cell lymphomas and solid tumors.
    Formula:C24H27N7O5S
    Purity:98.85%
    Color and Shape:Solid
    Molecular weight:525.58

    Ref: TM-T86106

    1mg
    86.00€
    5mg
    180.00€
    10mg
    279.00€
    25mg
    558.00€
    50mg
    912.00€
    100mg
    1,454.00€
    200mg
    1,882.00€
  • Antiviral agent 67

    CAS:
    Antiviralagent 67 (compound PC6) is an inhibitor of DENVNS5 (RNA-dependent RNA polymerase) with a Ki value of 1.12 nM.
    Formula:C19H19N3O
    Color and Shape:Solid
    Molecular weight:305.374

    Ref: TM-T206310

    10mg
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  • Polθ-IN-8

    CAS:
    Polθ-IN-8 (example 77) is a DNA polymerase θ (Polθ) inhibitor with an IC50 for Polθ ATPase activity of less than 100 nM. Polθ-IN-8 is useful for researching diseases related to Polθ activity, such as cancer.
    Formula:C22H22ClN7O3S
    Color and Shape:Solid
    Molecular weight:499.97

    Ref: TM-T207723

    10mg
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    50mg
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  • Polθ-IN-7

    CAS:
    Polθ-IN-7 (example 12) is an inhibitor of DNA polymerase θ (Polθ) with a Ki of 1.27 nM.
    Formula:C28H35F3N6O2
    Color and Shape:Solid
    Molecular weight:544.612

    Ref: TM-T204135

    10mg
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    50mg
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  • BAY-364

    CAS:
    BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+
    Formula:C23H19N3O4
    Color and Shape:Solid
    Molecular weight:401.41

    Ref: TM-T73451

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • Antitumor agent-74


    Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.
    Formula:C26H23FN6
    Color and Shape:Solid
    Molecular weight:438.5

    Ref: TM-T62509

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • RECTAS-2.0

    CAS:

    RECTAS-2.0 is a small molecule designed to correct RNA mis-splicing caused by the GLA c.639+919G>A mutation, intended for research in Fabry disease.

    Formula:C18H17ClN4O4
    Color and Shape:Solid
    Molecular weight:388.805

    Ref: TM-T206725

    10mg
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    50mg
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  • 4,5'-Dimethylangelicin-NHS


    NHS-modified coumarin, 4,5'-Dimethylangelicin-NHS, shows photochemical activity & photosensitivity.
    Formula:C21H19NO7S
    Color and Shape:Solid
    Molecular weight:429.44

    Ref: TM-T62365

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • ddCTP trisodium


    ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.
    Formula:C9H13N3Na3O12P3
    Color and Shape:Solid
    Molecular weight:517.1

    Ref: TM-T63602

    25mg
    2,160.00€
  • Zorubicin

    CAS:
    Zorubicin, a Daunorubicin derivative, targets topoisomerase II, inhibits DNA polymerase, and researches acute leukemia, sarcomas.
    Formula:C34H35N3O10
    Color and Shape:Solid
    Molecular weight:645.66

    Ref: TM-T69130

    25mg
    4,069.00€
    50mg
    5,383.00€
    100mg
    7,650.00€
  • Ladirubicin

    CAS:
    Ladirubicin, as an anthracyclines analog is the leading compound of alkylcyclines.
    Formula:C29H31NO11S
    Color and Shape:Solid
    Molecular weight:601.62

    Ref: TM-T32534

    25mg
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    50mg
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    100mg
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  • 2'-(2-Nitrobenzyl)-ATP

    CAS:
    2'-(2-Nitrobenzyl)-ATP is an analog of rATP. It acts as a transcription terminator by inhibiting the elongation of RNA chains by T7 RNA polymerase.
    Formula:C17H21N6O15P3
    Color and Shape:Solid
    Molecular weight:642.30

    Ref: TM-T207643

    10mg
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    50mg
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  • VPC-80051

    CAS:
    VPC-80051 is an hnRNP A1 splicing activity inhibitor that directly interacts with the hnRNP A1 RBD and reduces AR-V7 messenger levels in the 22Rv1 CRPC cell line. VPC-80051 is applicable in prostate cancer research.
    Formula:C16H13F2N3O
    Color and Shape:Solid
    Molecular weight:301.291

    Ref: TM-T204737

    10mg
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    50mg
    To inquire
  • Antimalarial agent 44


    Antimalarial agent 44 (Compound 3) is an antiparasitic agent effective against malaria. It exhibits good permeability in MDCK-MDR1 cell monolayers and has a high clearance rate in mouse liver microsomes.
    Formula:C37H37N5O7
    Color and Shape:Solid
    Molecular weight:663.72

    Ref: TM-T201453

    10mg
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    50mg
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  • PCNA-IN-1

    CAS:
    PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.
    Formula:C19H18I3NO3
    Color and Shape:Solid
    Molecular weight:689.065

    Ref: TM-T204170

    10mg
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    50mg
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  • 2-CEES

    CAS:
    2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.
    Formula:C4H9ClS
    Color and Shape:Solid
    Molecular weight:124.632

    Ref: TM-T204286

    10mg
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    50mg
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  • Eprociclovir Na

    CAS:
    Eprociclovir Na (A-5021) is 15x stronger than acyclovir at inhibiting herpesviruses, showing promise for EHV1 and herpetic keratitis treatment.
    Formula:C11H14N5NaO3
    Color and Shape:Solid
    Molecular weight:287.25

    Ref: TM-T69817

    25mg
    2,043.00€
    50mg
    2,682.00€
    100mg
    3,600.00€
  • CTPS1-IN-1

    CAS:
    CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.
    Formula:C21H22N6O4S2
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:486.57

    Ref: TM-T86105

    1mg
    163.00€
    5mg
    394.00€
    10mg
    620.00€
    25mg
    964.00€
    50mg
    1,288.00€
    100mg
    1,738.00€
    200mg
    2,367.00€
  • HRO761

    CAS:
    HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.
    Formula:C31H31ClF3N9O5
    Purity:98.74% - 99.62%
    Color and Shape:Solid
    Molecular weight:702.08

    Ref: TM-T72107

    1mg
    57.00€
    5mg
    118.00€
    10mg
    167.00€
    25mg
    280.00€
    50mg
    475.00€
    100mg
    708.00€
    1mL*10mM (DMSO)
    778.00€
  • SR 11302

    CAS:
    SR 11302 is an inhibitor of activator protein-1 (AP-1).
    Formula:C26H32O2
    Purity:98.65%
    Color and Shape:Solid
    Molecular weight:376.53

    Ref: TM-T23384

    1mg
    87.00€
    5mg
    144.00€
    10mg
    216.00€
    25mg
    376.00€
    50mg
    620.00€
    100mg
    938.00€
    1mL*10mM (DMSO)
    159.00€
  • Ethynylcytidine

    CAS:
    Ethynylcytidine is a nucleoside antimetabolite.
    Formula:C11H13N3O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:267.24

    Ref: TM-TQ0006

    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product
  • 5'-DMT-3'-TBDMS-ibu-rG

    CAS:
    5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside employed in deoxyribonucleic acid (DNA) synthesis.
    Formula:C41H51N5O8Si
    Color and Shape:Solid
    Molecular weight:769.96

    Ref: TM-T40919

    ne
    Discontinued
    Discontinued product
  • 5'-O-DMT-N6-ibu-dA

    CAS:
    5'-O-DMT-N6-ibu-dA can be utilized in the synthesis of oligodeoxyribonucleotides.
    Formula:C35H37N5O6
    Color and Shape:Solid
    Molecular weight:623.71

    Ref: TM-T39332

    ne
    Discontinued
    Discontinued product
  • NSC639828

    CAS:
    NSC639828 is an efficient inhibitor of DNA polymerase α, exhibiting a remarkable IC50 value of 70 μM. Additionally, NSC639828 demonstrates substantial antitumor activity, making it a promising candidate for cancer research.
    Formula:C18H13BrClN5O3
    Color and Shape:Solid
    Molecular weight:462.69

    Ref: TM-T38742

    ne
    Discontinued
    Discontinued product
  • MitoE10

    CAS:
    MitoE10 is an effective mitochondrial targeting antioxidant.
    Formula:C42H55O5PS
    Color and Shape:Solid
    Molecular weight:702.92

    Ref: TM-T33406

    25mg
    Discontinued
    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product