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DNA/RNA Synthesis

DNA/RNA Synthesis

Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.

Found 706 products of "DNA/RNA Synthesis"

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  • RAD51-IN-7

    CAS:
    <p>RAD51-IN-7 inhibits RAD51 gene, with potential for mitochondrial disorders. (From WO2021164746A1, cmpd 71)</p>
    Formula:C25H31N5O4S2
    Color and Shape:Solid
    Molecular weight:529.67
  • T-2513 hydrochloride

    CAS:
    <p>T-2513 hydrochloride: selective topoisomerase I inhibitor, binds DNA complex, halts DNA/RNA synthesis, causes cell death.</p>
    Formula:C25H28ClN3O5
    Color and Shape:Solid
    Molecular weight:485.96
  • RAD51-IN-8


    <p>RAD51-IN-8 inhibits RAD51-BRCA2 interaction and H4A4 with EC50 of 19 μM; a micromolar PPI inhibitor.</p>
    Formula:C16H14Cl2FN3O2
    Color and Shape:Solid
    Molecular weight:370.21
  • CYP2C19-IN-1


    <p>CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.</p>
    Formula:C26H26N2O6S
    Color and Shape:Solid
    Molecular weight:494.56
  • BAY-364

    CAS:
    <p>BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+</p>
    Formula:C23H19N3O4
    Color and Shape:Solid
    Molecular weight:401.41
  • UMPK ligand 1

    CAS:
    <p>UMPK ligand 1 (ZINC07785412) serves as a ligand for uridine monophosphate kinase (UMPK).</p>
    Formula:C15H22N4O5S
    Color and Shape:Solid
    Molecular weight:370.424
  • Plevitrexed

    CAS:
    <p>Plevitrexed, an oral TS inhibitor (Ki: 0.44 nM), targets α-folate receptor &amp; reduced folate carrier, treats gastric cancer.</p>
    Formula:C26H25FN8O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:532.53
  • Methyl 3-oxodecanoate

    CAS:
    <p>Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.</p>
    Formula:C11H20O3
    Color and Shape:Solid
    Molecular weight:200.275
  • Zorubicin

    CAS:
    <p>Zorubicin, a Daunorubicin derivative, targets topoisomerase II, inhibits DNA polymerase, and researches acute leukemia, sarcomas.</p>
    Formula:C34H35N3O10
    Color and Shape:Solid
    Molecular weight:645.66
  • Dencatistat

    CAS:
    <p>Dencatistat is a highly selective and oral cytidine triphosphate synthase 1 CTPS1 inhibitor specific.CTPS1-IN-2 for B-cell, T-cell lymphomas and solid tumors.</p>
    Formula:C24H27N7O5S
    Purity:98.85%
    Color and Shape:Solid
    Molecular weight:525.58
  • (R)-CSN5i-3

    CAS:
    <p>(R)-CSN5i-3 is CSN5i-3 of the R configuration.</p>
    Formula:C28H29F2N5O2
    Purity:99.76% - 99.97%
    Color and Shape:Solid
    Molecular weight:505.56
  • DIDS

    CAS:
    <p>DIDS inhibits anion exchangers reversibly then irreversibly and blocks RAD51.</p>
    Formula:C16H10N2O6S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:454.52
  • Epolactaene

    CAS:
    <p>Epolactaene: neuritogenic, inhibits mammalian DNA polymerases &amp; human DNA topoisomerase II.</p>
    Formula:C21H27NO6
    Color and Shape:Solid
    Molecular weight:389.44
  • 5-Methylcytosine hydrochloride

    CAS:
    <p>5-Methylcytosine hydrochloride plays a critical role in regulating gene expression, promoting genomic imprinting, and inhibiting transposon factors. It is also closely associated with translation fidelity and tRNA recognition.</p>
    Formula:C5H8ClN3O
    Color and Shape:Solid
    Molecular weight:161.59
  • Antiviral agent 67

    CAS:
    <p>Antiviralagent 67 (compound PC6) is an inhibitor of DENVNS5 (RNA-dependent RNA polymerase) with a Ki value of 1.12 nM.</p>
    Formula:C19H19N3O
    Color and Shape:Solid
    Molecular weight:305.374
  • DHX9-IN-19

    CAS:
    <p>DHX9-IN-19 (compound 3) is an orally active inhibitor of DHX9, playing a significant role in cancer research.</p>
    Formula:C20H21ClN4O4S2
    Color and Shape:Solid
    Molecular weight:480.988
  • L-2'-Fd4C

    CAS:
    <p>L-2'-Fd4C is an L-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity [1].</p>
    Formula:C9H10FN3O3
    Color and Shape:Solid
    Molecular weight:227.19
  • Ladirubicin

    CAS:
    <p>Ladirubicin, as an anthracyclines analog is the leading compound of alkylcyclines.</p>
    Formula:C29H31NO11S
    Color and Shape:Solid
    Molecular weight:601.62
  • Pol I-IN-1


    <p>Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition</p>
    Formula:C23H22N4O2
    Color and Shape:Solid
    Molecular weight:386.45
  • Polθ-IN-8

    CAS:
    <p>Polθ-IN-8 (example 77) is a DNA polymerase θ (Polθ) inhibitor with an IC50 for Polθ ATPase activity of less than 100 nM. Polθ-IN-8 is useful for researching diseases related to Polθ activity, such as cancer.</p>
    Formula:C22H22ClN7O3S
    Color and Shape:Solid
    Molecular weight:499.97