DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 798 products of "DNA/RNA Synthesis"
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PCNA-IN-1
CAS:PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.Formula:C19H18I3NO3Color and Shape:SolidMolecular weight:689.065DNA polymerase-IN-6
CAS:DNA polymerase-IN-6 (Compound 27) exhibits inhibitory activity against DNA polymerase, with EC50 values of 0.33 µM for HCMV, 1.9 µM for HSV-1, 0.76 µM for HSV-2, and 0.066 µM for EBV.Formula:C26H28ClFN8O4Color and Shape:SolidMolecular weight:571.003WRN inhibitor 13
CAS:WRN inhibitor 13 is an inhibitor of the WRN helicase with a pIC50 value ranging from 6 to 7.Formula:C16H20N2O5SColor and Shape:SolidMolecular weight:352.4052-CEES
CAS:2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.Formula:C4H9ClSColor and Shape:SolidMolecular weight:124.632And1 degrader 1
CAS:And1 degrader 1 (Compound A15) is a degrader of acidic nucleoplasmic DNA-binding protein 1 (And1) that notably induces degradation of And1 in NSCLC cells. When combined with Olaparib (1 μM), And1 degrader 1 at a concentration of 5 μM effectively inhibits proliferation in A549 and H460 cells. This compound is applicable in cancer research studies.Formula:C26H27Cl2N3OColor and Shape:SolidMolecular weight:468.42RAD51-IN-8
RAD51-IN-8 inhibits RAD51-BRCA2 interaction and H4A4 with EC50 of 19 μM; a micromolar PPI inhibitor.Formula:C16H14Cl2FN3O2Color and Shape:SolidMolecular weight:370.21iPAF1C
CAS:iPAF1C is a powerful inhibitor of the polymerase-associated factor 1 complex (PAF1C) and exhibits anti-HIV activity [1].
Formula:C27H26BrFN4OColor and Shape:SolidMolecular weight:521.42DIDS
CAS:DIDS inhibits anion exchangers reversibly then irreversibly and blocks RAD51.Formula:C16H10N2O6S4Purity:98%Color and Shape:SolidMolecular weight:454.52Antitumor agent-75
Antitumor agent-75 is a novel and potent antitumor agent.Formula:C26H23FN6Color and Shape:SolidMolecular weight:438.5Methyl 3-oxodecanoate
CAS:Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.
Formula:C11H20O3Color and Shape:SolidMolecular weight:200.275HRO761
CAS:HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.Formula:C31H31ClF3N9O5Purity:98.74% - 99.62%Color and Shape:SolidMolecular weight:702.08Ref: TM-T72107
1mg57.00€5mg118.00€10mg167.00€25mg280.00€50mg475.00€100mg708.00€1mL*10mM (DMSO)778.00€CTPS1-IN-1
CAS:CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.Formula:C21H22N6O4S2Purity:99.46%Color and Shape:SolidMolecular weight:486.57SR 11302
CAS:SR 11302 is an inhibitor of activator protein-1 (AP-1).Formula:C26H32O2Purity:98.65%Color and Shape:SolidMolecular weight:376.53Ref: TM-T23384
1mg87.00€5mg144.00€10mg216.00€25mg376.00€50mg620.00€100mg938.00€1mL*10mM (DMSO)159.00€5'-O-DMT-N6-ibu-dA
CAS:5'-O-DMT-N6-ibu-dA can be utilized in the synthesis of oligodeoxyribonucleotides.Formula:C35H37N5O6Color and Shape:SolidMolecular weight:623.715'-DMT-3'-TBDMS-ibu-rG
CAS:5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside employed in deoxyribonucleic acid (DNA) synthesis.Formula:C41H51N5O8SiColor and Shape:SolidMolecular weight:769.96Ethynylcytidine
CAS:Ethynylcytidine is a nucleoside antimetabolite.Formula:C11H13N3O5Purity:98%Color and Shape:SolidMolecular weight:267.24NSC639828
CAS:NSC639828 is an efficient inhibitor of DNA polymerase α, exhibiting a remarkable IC50 value of 70 μM. Additionally, NSC639828 demonstrates substantial antitumor activity, making it a promising candidate for cancer research.Formula:C18H13BrClN5O3Color and Shape:SolidMolecular weight:462.69MitoE10
CAS:MitoE10 is an effective mitochondrial targeting antioxidant.Formula:C42H55O5PSColor and Shape:SolidMolecular weight:702.92
