DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 706 products of "DNA/RNA Synthesis"
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5'-O-TBDMS-dA
CAS:<p>5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formula:C16H27N5O3SiColor and Shape:SolidMolecular weight:365.509KWR137
<p>KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.</p>Formula:C33H31ClF3N9O4Color and Shape:SolidMolecular weight:710.105RNA polymerase II-IN-2
<p>RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.</p>Formula:C41H58N10O12SColor and Shape:SolidMolecular weight:915.02wrwycr-NH2 TFA
<p>wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.</p>Color and Shape:Odour SolidHDAC-IN-85
<p>HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.</p>Formula:C24H27FN4O5Color and Shape:SolidMolecular weight:470.49WRN inhibitor 17
CAS:<p>WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.</p>Formula:C33H34F4N4O6SColor and Shape:SolidMolecular weight:690.71Chrexanthomycin C
<p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>Formula:C31H24O15Color and Shape:SolidMolecular weight:636.51IBU-DC Phosphoramidite
CAS:<p>IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.</p>Formula:C43H54N5O8PColor and Shape:SolidMolecular weight:799.906Nusinersen
CAS:<p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>Purity:98.62%Color and Shape:SolidCarboxy-pyridostatin
CAS:<p>Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.</p>Formula:C35H34N10O7Color and Shape:SolidMolecular weight:706.71ML-60218
CAS:<p>ML-60218 inhibits RNA pol III in yeast/humans with IC50s of 32/27 μM; disrupts and prevents viroplasms.</p>Formula:C19H15Cl2N3O2S2Purity:98.1%Color and Shape:SolidMolecular weight:452.38SD49-7
CAS:<p>SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 µM.</p>Formula:C18H14N2O3Purity:99.91%Color and Shape:SoildMolecular weight:306.32PAT-LM1
<p>PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.</p>Color and Shape:Odour Liquid5-Methylcytidine 5′-triphosphate trisodium
<p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>Formula:C10H15N3Na3O14P3Color and Shape:SolidMolecular weight:563.13Carbazole
CAS:<p>Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.</p>Formula:C12H9NPurity:99.82%Color and Shape:SolidMolecular weight:167.211Garenoxacin
CAS:<p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>Formula:C23H20F2N2O4Purity:98%Color and Shape:SolidMolecular weight:426.41CTP Synthetase-IN-1 Ammonium salt
<p>CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infections</p>Formula:C20H22F3N7O3S2Purity:99.97%Color and Shape:SolidMolecular weight:529.56Lorutengitide
CAS:<p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>Formula:C30H50N8O12Color and Shape:SolidMolecular weight:714.764Ac-rC Phosphoramidite
CAS:<p>Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.</p>Formula:C47H64N5O9PSiPurity:98.29%Color and Shape:SolidMolecular weight:902.1Brr2-IN-2
<p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>Formula:C21H25FN4O2Color and Shape:SolidMolecular weight:384.45
