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DNA/RNA Synthesis

DNA/RNA Synthesis

Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.

Found 706 products of "DNA/RNA Synthesis"

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  • KWR137


    <p>KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.</p>
    Formula:C33H31ClF3N9O4
    Color and Shape:Solid
    Molecular weight:710.105
  • Cytarabine triphosphate

    CAS:
    <p>Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.</p>
    Formula:C9H16N3O14P3
    Color and Shape:Solid
    Molecular weight:483.16
  • AV-153

    CAS:
    <p>AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.</p>
    Formula:C14H19NNaO6
    Color and Shape:Solid
    Molecular weight:320.297
  • m7GpppGmpG

    CAS:
    <p>m7GpppGmpG, a trinucleotide 5′ cap analog, exhibits capping efficiencies of 86% for the RNAs obtained [1].</p>
    Formula:C32H43N15O25P4
    Color and Shape:Solid
    Molecular weight:1161.66
  • RNA splicing modulator 2

    CAS:
    <p>RNA splicing modulator 2 (compound 256) is a RNA splicing modulator [1] .</p>
    Formula:C20H21N5OS
    Color and Shape:Solid
    Molecular weight:379.48
  • Cy5-dATP


    <p>Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] .</p>
    Formula:C47H58N7O19P3S2
    Color and Shape:Solid
    Molecular weight:1182.05
  • EFdA-TP

    CAS:
    <p>EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.</p>
    Formula:C12H15FN5O12P3
    Color and Shape:Solid
    Molecular weight:533.195
  • 5'-O-DMT-2'-O-TBDMS-Ac-rC

    CAS:
    <p>5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C38H47N3O8Si
    Color and Shape:Solid
    Molecular weight:701.892
  • 5-Iminodaunorubicin

    CAS:
    <p>5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.</p>
    Formula:C27H30N2O9
    Color and Shape:Solid
    Molecular weight:526.54
  • Chrexanthomycin C


    <p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>
    Formula:C31H24O15
    Color and Shape:Solid
    Molecular weight:636.51
  • RNA polymerase II-IN-2


    <p>RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.</p>
    Formula:C41H58N10O12S
    Color and Shape:Solid
    Molecular weight:915.02
  • Thailanstatin C

    CAS:
    <p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>
    Formula:C30H46ClNO9
    Color and Shape:Solid
    Molecular weight:600.15
  • Pseudorabies virus-IN-1


    <p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>
    Formula:C27H23ClF2N4O2
    Color and Shape:Solid
    Molecular weight:508.947
  • 5'-O-DMT-N4-Ac-2'-F-dC

    CAS:
    <p>5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C32H32FN3O7
    Color and Shape:Solid
    Molecular weight:589.61
  • 3'Ome-m7GpppAmpG

    CAS:
    <p>3'Ome-m7GpppAmpG is a trinucleotide cap with LNA, boosting translation; useful in mRNA vaccines and gene therapy.</p>
    Formula:C33H45N15O24P4
    Color and Shape:Solid
    Molecular weight:1159.69
  • 5'-O-DMT-N4-Bz-2'-F-dC

    CAS:
    <p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>
    Formula:C37H34FN3O7
    Color and Shape:Solid
    Molecular weight:651.68
  • (S)-DI-87

    CAS:
    <p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor,reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>
    Formula:C23H30N6O3S2
    Purity:99.42%
    Color and Shape:Soild
    Molecular weight:502.65
  • Ac-dA Phosphoramidite

    CAS:
    <p>Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>
    Formula:C42H50N7O7P
    Color and Shape:Solid
    Molecular weight:795.878
  • SR15006

    CAS:
    <p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>
    Formula:C16H20ClN3O4S
    Purity:99.87%
    Color and Shape:Soild
    Molecular weight:385.87
  • 5'-O-DMT-PAC-dA

    CAS:
    <p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>
    Formula:C39H37N5O7
    Color and Shape:Solid
    Molecular weight:687.74