DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 802 products of "DNA/RNA Synthesis"
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CGP 53353
CAS:CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.Formula:C20H13F2N3O2Purity:98.11%Color and Shape:SolidMolecular weight:365.33TDRL-X80
CAS:TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).Formula:C23H15ClN2O6Color and Shape:SolidMolecular weight:450.83JFN05510
CAS:Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.Formula:C50H68N7O9PSiColor and Shape:SolidMolecular weight:970.18HIV-1 inhibitor-43
CAS:HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), <0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.Formula:C24H21ClN2O4SColor and Shape:SolidMolecular weight:468.95Cylindrospermopsin
CAS:Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.Formula:C15H21N5O7SColor and Shape:SolidMolecular weight:415.42EGFR/HER2/TS-IN-2
CAS:EGFR/HER2/TS-IN-2: Strong EGFR, HER2 & TS inhibitor; EGFR IC50=0.173μM, HER2 IC50=0.125μM, TS IC50=1.12μM; kills MDA-MB-231 cells (IC50=1.69μM).Formula:C26H21N7OS2Color and Shape:SolidMolecular weight:511.62FLDP-5
CAS:FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.Formula:C21H21NO5Color and Shape:SolidMolecular weight:367.4HBV-IN-21
CAS:HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).Formula:C17H17FN4OS2Color and Shape:SolidMolecular weight:376.47CAY10760
CAS:CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.Formula:C28H24ClN3O3Color and Shape:SolidMolecular weight:485.96cp028
CAS:cp028 inhibits pre-mRNA splicing in vitro.Formula:C23H17FN2O4Color and Shape:SolidMolecular weight:404.395,10-Dideazaaminopterin
CAS:5,10-Dideazaaminopterin is an antileukemic drug.Formula:C21H22N6O5Purity:98%Color and Shape:SolidMolecular weight:438.44HBV-IN-14
CAS:HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).Formula:C22H21ClN2O5Color and Shape:SolidMolecular weight:428.87MMV688845
CAS:MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.Formula:C24H25N3O3SColor and Shape:SolidMolecular weight:435.54Antibacterial agent 124
CAS:Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.Formula:C16H17ClFN3O2Color and Shape:SolidMolecular weight:337.78HBV-IN-15
CAS:HBV-IN-15, a flavone derivative, is a potent cccDNA inhibitor, potentially aiding HBV research.Formula:C24H23ClO6Color and Shape:SolidMolecular weight:442.89ML372
CAS:ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.Formula:C18H20N2O4SColor and Shape:SolidMolecular weight:360.43Fozivudine tidoxil
CAS:Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C35H64N5O8PSColor and Shape:SolidMolecular weight:745.95UIAA-II-232
CAS:UIAA-II-232 (compound 19b) is a potent inhibitor of DNA gyrase catalytic (IC 50= 3.5 μM).Formula:C20H24FN5O3Color and Shape:SolidMolecular weight:401.43HBV-IN-16
CAS:HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).Formula:C22H20ClNO4Color and Shape:SolidMolecular weight:397.85Crisnatol mesylate
CAS:Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.Formula:C24H27NO5SColor and Shape:SolidMolecular weight:441.54Werner syndrome RecQ helicase-IN-3
CAS:Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.Formula:C31H30ClF3N8O5Color and Shape:SolidMolecular weight:687.07Antitumor agent-85
Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.Formula:C24H33N7Color and Shape:SolidMolecular weight:419.57CB 3717
CAS:CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.Formula:C24H23N5O6Color and Shape:SolidMolecular weight:477.47IACS-4759
CAS:IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.Formula:C10H17N3O2Color and Shape:SolidMolecular weight:211.26ERCC1-XPF-IN-1
CAS:ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.Formula:C28H32ClN5O2Color and Shape:SolidMolecular weight:506.04HBV-IN-4
CAS:HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.Formula:C24H19ClFN5O3Color and Shape:SolidMolecular weight:479.89MLAF50
CAS:MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.Formula:C15H12I2O4Color and Shape:SolidMolecular weight:510.06Beaucage reagent
CAS:Beaucage reagent, which is found to be effective in causing DNA cleavage.Formula:C7H4O3S2Purity:98.50%Color and Shape:White To Off-White PowderMolecular weight:200.233'-Deoxyuridine-5'-triphosphate
CAS:3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.Formula:C9H15N2O14P3Color and Shape:SolidMolecular weight:468.14DENV-IN-4
CAS:DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.Formula:C28H32N4O4SiColor and Shape:SolidMolecular weight:516.66Crisnatol
CAS:Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.Formula:C23H23NO2Color and Shape:SolidMolecular weight:345.43DHX9-IN-1
CAS:DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].Formula:C21H21F2N5O3SColor and Shape:SolidMolecular weight:461.49Ref: TM-T82569
1mg205.00€5mg528.00€10mg782.00€25mg1,161.00€50mg1,558.00€100mg2,322.00€1mL*10mM (DMSO)537.00€Thiarabine
CAS:Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.Formula:C9H13N3O4SPurity:98%Color and Shape:SolidMolecular weight:259.28Zelpolib
CAS:Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.Formula:C22H21N3O5S2Purity:98.79%Color and Shape:SolidMolecular weight:471.55AS-136A
CAS:AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.Formula:C17H19F3N4O3SPurity:98.52%Color and Shape:SolidMolecular weight:416.42Ref: TM-T62160
1mg215.00€5mg537.00€10mg802.00€25mg1,369.00€50mg1,783.00€100mg2,395.00€1mL*10mM (DMSO)590.00€HIPP
CAS:HIPP is a highly selective inhibitor of antineoplastic CtBP.Formula:C9H9NO3Color and Shape:SolidMolecular weight:179.17NPD9948
CAS:NPD9948 is a competitive inhibitor of MTH1.Formula:C13H14N6Color and Shape:SolidMolecular weight:254.29REV7/REV3L-IN-1
CAS:REV7/REV3L-IN-1 is a inhibitor of REV7/REV3L interaction(IC50 of 78 μM),Formula:C19H21N3O3SPurity:98%Color and Shape:SolidMolecular weight:371.45AB-182
CAS:AB-182 is an aziridine derivative with antitumor activity.Formula:C11H22N3O4PColor and Shape:SolidMolecular weight:291.28Picoplatin
CAS:Picoplatin, an anti-cancer agent overcoming platinum resistance, alkylates DNA to block replication, transcription, and induce apoptosis.Formula:C6H10Cl2N2PtPurity:98%Color and Shape:SolidMolecular weight:376.14HHL-6
CAS:HHL-6 is a c-Fos and BDNF protein expression modulator.Formula:C19H26N2O3Color and Shape:SolidMolecular weight:330.42BzDANP
CAS:BzDANP is a modulator of pre-miR-29a maturation by Dicer.Formula:C18H24N6Color and Shape:SolidMolecular weight:324.42SEC inhibitor KL-2
CAS:KL-2: potent SEC inhibitor, selectively disrupts AFF4-CCNT1, dose-dependent, Ki: 1.50 μM.Formula:C17H13ClFNO3Purity:99.86%Color and Shape:SolidMolecular weight:333.74AM-TS23
CAS:AM-TS23 is used as a DNA polymerase lambda and beta inhibitor.Formula:C17H12N2O3S3Purity:98%Color and Shape:SolidMolecular weight:388.48ML366
CAS:ML366 is a Vibrio cholerae Quorum Sensing inhibitor Acting via the LuxO response regulator.Formula:C17H19N3O4Purity:98%Color and Shape:SolidMolecular weight:329.35Meturedepa
CAS:Meturedepa is an antineoplastic agent.Formula:C11H22N3O3PPurity:98%Color and Shape:SolidMolecular weight:275.28Codon readthrough inducer 1
CAS:Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.Formula:C15H11N3O5Purity:98%Color and Shape:SolidMolecular weight:313.26MS0017509
CAS:MS0017509 is a DNA damage repair inhibitor.Formula:C11H10N4Purity:98%Color and Shape:SolidMolecular weight:198.22JNJ-9676
CAS:JNJ-9676 is an orally active inhibitor of the coronavirus membrane protein, thereby blocking viral assembly and release.coronavirus and SARS-CoV.Formula:C28H21F2N5O2Purity:99.83%Color and Shape:SoildMolecular weight:497.5Ref: TM-T205924
1mg137.00€5mg330.00€10mg532.00€25mg1,108.00€50mg1,738.00€100mg2,592.00€1mL*10mM (DMSO)354.00€Homocarbonyltopsentin
CAS:Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.Formula:C21H14N4O3Purity:98%Color and Shape:SolidMolecular weight:370.36
