DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 673 products for "DNA/RNA Synthesis".
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WRN inhibitor 17
CAS:WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.Formula:C33H34F4N4O6SColor and Shape:SolidMolecular weight:690.71Demycarosyl-3D-β-D-digitoxosylmithramycin SK
CAS:Demycarosyl-3D-β-D-digitoxosylmithramycin SK, an analog of Mithramycin, exhibits potent anti-tumor activity.Formula:C50H72O23Color and Shape:SolidMolecular weight:1041.09Thymidine-D3
CAS:Thymidine-D3 is the deuterated form of Thymidine. It is a specific precursor of deoxyribonucleic acid (DNA) and functions as a cell synchronizing agent. Thymidine (TWP2911) acts as a DNA synthesis inhibitor, blocking cells at the G1/S boundary before DNA replication.Formula:C10H14N2O5Color and Shape:SolidMolecular weight:245.25Uridine triphosphate-15N2 dilithium
Uridine triphosphate-15N2 dilithium is the 15N-labeled version of uridine triphosphate. Uridine triphosphate (UTP; Uridine 5'-triphosphate) is a nucleotide that regulates functions related to pancreatic endocrine and exocrine behavior, proliferation, channels, transporters, and intracellular signaling under both normal and pathological conditions.Color and Shape:Odour SolidAdenine-13C5,15C5
Adenine-13C5,15C5 is the isotopically labeled form of adenine. This purine is one of the four nucleotide bases in DNA and is also a component of RNA. Adenine (T0064) is crucial in cellular respiration, the formation of ATP, coenzymes NAD and FAD, and protein synthesis.Color and Shape:Odour SolidMaleuric acid
CAS:Maleuric acid is an anti-mitotic agent for research and boosts growth and fertility in flora and fauna.Formula:C5H6N2O4Purity:99.80%Color and Shape:SolidMolecular weight:158.11ONX 0801 trisodium
CAS:ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.Formula:C32H30N5Na3O10Color and Shape:SolidMolecular weight:713.58SD49-7
CAS:SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 µM.Formula:C18H14N2O3Purity:99.91%Color and Shape:Yellow SolidMolecular weight:306.32Ref: TM-T67781
1mg57.00€5mg124.00€1mL*10mM (DMSO)141.00€10mg178.00€25mg359.00€50mg520.00€100mg745.00€500mg1,485.00€Guanosine 5'-triphosphate trisodium salt hydrate
CAS:5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.Formula:C10H18N5NaO15P3Purity:98%Color and Shape:SolidMolecular weight:564.1857-Deazaxanthine
CAS:7-Deazaxanthine (7DX) is an inhibitor of thymidine phosphorylase (TPase) and reduces TPase activity in a concentration-dependent manner, with an IC50 value of 40 μM. Additionally, 7-Deazaxanthine exhibits significant anti-angiogenic properties.Formula:C6H5N3O2Color and Shape:SolidMolecular weight:151.12Nitrosofolic acid
CAS:Nitrosofolic acid is a folic acid derivaive.Formula:C19H18N8O7Color and Shape:SolidMolecular weight:470.40Phen-DC3 Trifluoromethanesulfonate
CAS:Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.Formula:C36H26F6N6O8S2Purity:98%Color and Shape:SolidMolecular weight:848.75Lorutengitide
CAS:Lorutengitide is a transcription-regulating peptide with antiproliferative activity.Formula:C30H50N8O12Color and Shape:SolidMolecular weight:714.764FF-10502
CAS:FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.Formula:C9H12FN3O3SColor and Shape:SolidMolecular weight:261.27Ribonuclease T1
CAS:Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.Color and Shape:Solid2,5-Deoxyfructosazine (hydrochloride)
CAS:2,5-Deoxyfructosazine, a pyrazine in cured tobacco, flavors food and tobacco, inhibits IL-2, and breaks DNA strands.Formula:C12H20N2O7Color and Shape:SolidMolecular weight:304.3CW-2
CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).Formula:C43H42Cl2FN11O10PtColor and Shape:SolidMolecular weight:1156.21251Bisucaberin
CAS:Bisucaberin: a siderophore with anticancer properties; inhibits L1210/1MC cells and enhances 1023 cell cytolysis.Formula:C18H32N4O6Color and Shape:SolidMolecular weight:400.476MRK-952
MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.Formula:C20H20ClF3N6Color and Shape:SolidMolecular weight:436.8612'-(2-Nitrobenzyl)-ATP trisodium
2'-(2-Nitrobenzyl)-ATP trisodium is an rATP analogue that acts as a transcription terminator. It inhibits T7 RNA polymerase from continuing RNA chain extension.Formula:C17H18N6Na3O15P3Color and Shape:SolidMolecular weight:707.97361Tubercidin 5'-triphosphate tetrasodium
Tubercidin5'-triphosphate (7-Deazaadenosine 5'-triphosphate) tetrasodium is a nucleoside analogue and serves as an active metabolite of Tubercidin.Color and Shape:Odour SolidChrexanthomycin C
Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.Formula:C31H24O15Color and Shape:SolidMolecular weight:636.51RNA splicing modulator 1
CAS:RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].Formula:C19H20N6OSColor and Shape:SolidMolecular weight:380.47DNA31
CAS:DNA31 is a potent RNA polymerase inhibitor.Formula:C48H58N4O13Purity:98%Color and Shape:SolidMolecular weight:898.99ddATP tetrasodium
ddATP (2',3'-Dideoxyadenosine 5'-triphosphate) tetrasodium is an active metabolite of 2',3'-dideoxyinosine and functions as a chain elongation inhibitor for DNA polymerase. It is utilized in DNA sequencing using the Sanger method and in research related to viral infections.Formula:C10H12N5Na4O11P3Color and Shape:SolidMolecular weight:563.11Carboxy-pyridostatin
CAS:Carboxy-pyridostatin is a G- quadruplex ligand, which can stabilize G4 structure and inhibit cell proliferation.Formula:C35H34N10O7Color and Shape:SolidMolecular weight:706.71Clofarabine-5'-diphosphate trisodium
Clofarabine-5'-diphosphatetrisodium (Clofarabine-DP trisodium) is the sodium salt form of Clofarabine-5'-diphosphate. As a metabolic product of Clofarabine, it results from phosphorylation by deoxycytidine kinase (dCK). Clofarabine-5'-diphosphate trisodium can undergo further phosphorylation to form Clofarabine-5'-triphosphate, demonstrating cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.Formula:C10H10ClFN5Na3O9P2Color and Shape:SolidMolecular weight:529.58RNA splicing modulator 3
CAS:RNA Splicing Modulator 3 (Compound 236) is an effective RNA splicing modulator, exhibiting an AC50 value of less than 100 nM [1].Formula:C19H20N6OSColor and Shape:SolidMolecular weight:380.47Bromochloroacetonitrile
CAS:Bromochloroacetonitrile, a water disinfection by-product, is mutagenic and can break DNA strands.Formula:C2HBrClNColor and Shape:SolidMolecular weight:154.39PIF1-IN-1
PIF1-IN-1 (Compound 48) is an inhibitor of the hPIF1 helicase, with an IC50 value of 320 μM.Color and Shape:Odour SolidDeoxythymidine-5'-triphosphate sodium hydrate
dTTP sodium hydrate, a DNA synthesis component, is a nucleoside triphosphate.Formula:C10H17N2O14P3·xNa·xH2OColor and Shape:SolidMolecular weight:C10H17N2O14P3.xNa.xH2OAdeninobananin
CAS:Adeninobananin, a negative control tool, exhibits no inhibitory activity against the SARS Coronavirus helicase.Formula:C19H19ClN6O9Color and Shape:SolidMolecular weight:510.842'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium
2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium, an ATP analog, exhibits robust mixed-type inhibition of poly(AU) synthesis.Formula:C10H11FLi4N5O12P3Color and Shape:SolidMolecular weight:532.9UCK2 Inhibitor-3
CAS:UCK2 Inhibitor-3 blocks UCK2 (IC50: 16.6μM) and DNA polymerases eta/kappa (IC50s: 56μM/16μM), aiding uridine salvage in certain cells.Formula:C19H13BrFN5O2SColor and Shape:SolidMolecular weight:474.315-Iminodaunorubicin
CAS:5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.Formula:C27H30N2O9Color and Shape:SolidMolecular weight:526.54N6-Methyladenine
CAS:N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants.Formula:C6H7N5Purity:99.78%Color and Shape:SolidMolecular weight:149.15(+)-Glaucarubinone
(+)-Glaucarubinone is a natural product that can be used as a reference standard.Formula:C25H34O10Color and Shape:SolidMolecular weight:494.537Nuclease S1
CAS:Nuclease S1 breaks down ssDNA and RNA, trims protruding ends of dsDNA.Color and Shape:SolidAF-615
CAS:AF-615 is an innovative inhibitor of the CDT1/Geminin protein complex, capable of inducing DNA damage and cell death in cancer cells.Formula:C10H13N5O2SColor and Shape:SolidMolecular weight:267.31DG1
DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressingFormula:C19H17N5O5SColor and Shape:SolidMolecular weight:427.43F3 peptide
CAS:F3 peptide is a fragment of human high mobility group protein 2 (HMGB2) that specifically binds to nucleolin, expressed on the membranes of cancer cells, neovasculature, and endothelial cells. Serving as an effective ligand, F3 peptide enhances the druggability of macromolecular drugs or nanoparticles.Formula:C152H263N49O41Color and Shape:SolidMolecular weight:3433.02cis-Lomibuvir
CAS:cis-Lomibuvir (cis-VX-222) is a selective HCV NS5B RdRp inhibitor with a Kd of 17 nM and an EC50 of 5.2 nM, targeting thumb pocket 2.Formula:C25H35NO4SColor and Shape:SolidMolecular weight:445.61N1-Methylpseudouridine-5′-triphosphate tetralithium
N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.Formula:C10H13Li4N2O15P3Color and Shape:SolidMolecular weight:521.913-TP
13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.Formula:C12H19F2N6O12P3Color and Shape:SolidMolecular weight:570.23Pyrindamycin A
CAS:Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.Formula:C26H26ClN3O8Purity:98%Color and Shape:SolidMolecular weight:543.956PGD-IN-2
6PGD-IN-2 is a non-competitive inhibitor of 6-phosphogluconate dehydrogenase (6PGD) with an IC50 value of 5.1 μM. It disrupts 6PGD oligomerization in a substrate-dependent manner and induces the production of NADPH and Ru-5-P while reducing DNA synthesis in A549 cells. 6PGD-IN-2 is applicable in research on non-small cell cancer and liver cancer.Color and Shape:Odour SolidHOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt
CAS:HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.Formula:C57H62N8O10SColor and Shape:SolidMolecular weight:1051.21Brr2-IN-2
Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.Formula:C21H25FN4O2Color and Shape:SolidMolecular weight:384.45DMT-dG(ib) Phosphoramidite
CAS:DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.Formula:C44H54N7O8PPurity:99.21%Color and Shape:SolidMolecular weight:839.923'-Deoxyuridine-5'-triphosphate trisodium
3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).Formula:C9H12N2Na3O14P3Color and Shape:SolidMolecular weight:534.08
