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DNA/RNA Synthesis

DNA/RNA Synthesis

Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.

Found 706 products of "DNA/RNA Synthesis"

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  • 2'-OMe-Ac-C Phosphoramidite
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    2'-OMe-Ac-C Phosphoramidite

    CAS:
    <p>2'-OMe-Ac-C Phosphoramidite, a modified phosphoramidite, is utilized in the synthesis of oligonucleotides.</p>
    Formula:C42H52N5O9P
    Color and Shape:Solid
    Molecular weight:801.86

    Ref: TM-T75265

  • LB80317
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    LB80317

    CAS:
    <p>LB-80317, a DNA polymerase inhibitor, is used potentially for the potential treatment of hepatitis B virus infection.</p>
    Formula:C10H14N5O5P
    Color and Shape:Solid
    Molecular weight:315.22

    Ref: TM-T27801

  • Phen-DC3 Trifluoromethanesulfonate
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    Phen-DC3 Trifluoromethanesulfonate

    CAS:
    <p>Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.</p>
    Formula:C36H26F6N6O8S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:848.75

    Ref: TM-T13817L

  • MRK-952
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    MRK-952

    <p>MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.</p>
    Formula:C20H20ClF3N6
    Color and Shape:Solid
    Molecular weight:436.861

    Ref: TM-T205743

  • Pyrindamycin A
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    Pyrindamycin A

    CAS:
    <p>Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.</p>
    Formula:C26H26ClN3O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:543.95

    Ref: TM-T12590

  • GS-443902 trisodium
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    GS-443902 trisodium

    CAS:
    <p>GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.</p>
    Formula:C12H16N5O13P3·xNa
    Color and Shape:Solid

    Ref: TM-T38761

  • Guanosine triphosphate
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    Guanosine triphosphate

    CAS:
    <p>Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].</p>
    Formula:C10H16N5O14P3
    Color and Shape:Solid
    Molecular weight:523.18

    Ref: TM-T73596

  • RNA splicing modulator 2
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    RNA splicing modulator 2

    CAS:
    <p>RNA splicing modulator 2 (compound 256) is a RNA splicing modulator [1] .</p>
    Formula:C20H21N5OS
    Color and Shape:Solid
    Molecular weight:379.48

    Ref: TM-T74885

  • 5-BrdUTP sodium salt
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    5-BrdUTP sodium salt

    CAS:
    <p>5-BrdUTP sodium salt is a TdT substrate that can be used to label the DNA double-strand breaks.</p>
    Formula:C9H10BrN2Na4O14P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:634.97

    Ref: TM-T19149

  • 7-TFA-ap-7-Deaza-ddG
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    7-TFA-ap-7-Deaza-ddG

    CAS:
    <p>Compound 19d, a nucleotide derivative, is used to make thiotriphosphate dye terminators for DNA sequencing.</p>
    Formula:C16H16F3N5O4
    Color and Shape:Solid
    Molecular weight:399.33

    Ref: TM-T38531

  • Clofarabine-5'-triphosphate
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    Clofarabine-5'-triphosphate

    CAS:
    <p>Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.</p>
    Formula:C10H14ClFN5O12P3
    Color and Shape:Solid
    Molecular weight:543.62

    Ref: TM-T203136

  • 5'-O-DMT-Bz-rC
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    5'-O-DMT-Bz-rC

    CAS:
    <p>5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C37H35N3O8
    Color and Shape:Solid
    Molecular weight:649.69

    Ref: TM-T37135

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    HDAC-IN-85

    <p>HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.</p>
    Formula:C24H27FN4O5
    Color and Shape:Solid
    Molecular weight:470.49

    Ref: TM-T205411

  • 5'-O-DMT-PAC-dA
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    5'-O-DMT-PAC-dA

    CAS:
    <p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>
    Formula:C39H37N5O7
    Color and Shape:Solid
    Molecular weight:687.74

    Ref: TM-T37139

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    CW-2

    <p>CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).</p>
    Formula:C43H42Cl2FN11O10Pt
    Color and Shape:Solid
    Molecular weight:1156.21251

    Ref: TM-T207351

  • Thailanstatin C
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    Thailanstatin C

    CAS:
    <p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>
    Formula:C30H46ClNO9
    Color and Shape:Solid
    Molecular weight:600.15

    Ref: TM-T38890

  • Bz-rC Phosphoramidite
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    Bz-rC Phosphoramidite

    CAS:
    <p>Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>
    Formula:C52H66N5O9PSi
    Color and Shape:Solid
    Molecular weight:964.185

    Ref: TM-T38566

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    wrwyar-NH2 TFA

    <p>wrwyar-NH2 (TFA) serves as the control peptide for wrwycr-NH2.</p>
    Color and Shape:Odour Solid

    Ref: TM-TP3210

  • Ac-rC Phosphoramidite
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    Ac-rC Phosphoramidite

    CAS:
    <p>Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.</p>
    Formula:C47H64N5O9PSi
    Purity:98.29%
    Color and Shape:Solid
    Molecular weight:902.1

    Ref: TM-T36687

  • Carbazole
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    Carbazole

    CAS:
    <p>Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.</p>
    Formula:C12H9N
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:167.211

    Ref: TM-PDK0380

  • KWR137
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    KWR137

    <p>KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.</p>
    Formula:C33H31ClF3N9O4
    Color and Shape:Solid
    Molecular weight:710.105

    Ref: TM-T205674

  • 5'-O-DMT-rI
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    5'-O-DMT-rI

    CAS:
    <p>5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].</p>
    Formula:C31H30N4O7
    Color and Shape:Solid
    Molecular weight:570.59

    Ref: TM-T37140

  • 16,16-dimethyl Prostaglandin A1
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    16,16-dimethyl Prostaglandin A1

    CAS:
    <p>16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.</p>
    Formula:C22H36O4
    Color and Shape:Solid
    Molecular weight:364.526

    Ref: TM-T36040

  • Diguanosine 5′-triphosphate
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    Diguanosine 5′-triphosphate

    CAS:
    <p>Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase.</p>
    Formula:C20H27N10O18P3
    Color and Shape:Solid
    Molecular weight:788.409

    Ref: TM-T40776

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    Brr2-IN-2

    <p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>
    Formula:C21H25FN4O2
    Color and Shape:Solid
    Molecular weight:384.45

    Ref: TM-T205260

  • CymitQuimica logo
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    13-TP

    <p>13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.</p>
    Formula:C12H19F2N6O12P3
    Color and Shape:Solid
    Molecular weight:570.23

    Ref: TM-T205409

  • CymitQuimica logo
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    RNA polymerase II-IN-2

    <p>RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.</p>
    Formula:C41H58N10O12S
    Color and Shape:Solid
    Molecular weight:915.02

    Ref: TM-T74631

  • 5-Methylcytidine 5′-triphosphate
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    5-Methylcytidine 5′-triphosphate

    CAS:
    <p>5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innate</p>
    Formula:C10H18N3O14P3
    Color and Shape:Solid
    Molecular weight:497.18

    Ref: TM-T74584

  • 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
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    2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

    CAS:
    <p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>
    Formula:C10H14N5Na2O8P
    Color and Shape:Solid
    Molecular weight:409.202

    Ref: TM-T35652

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    wrwycr-NH2 TFA

    <p>wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.</p>
    Color and Shape:Odour Solid

    Ref: TM-TP3227

  • Guanosine 5'-triphosphate trisodium salt hydrate
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    Guanosine 5'-triphosphate trisodium salt hydrate

    CAS:
    <p>5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.</p>
    Formula:C10H18N5NaO15P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:564.185

    Ref: TM-T10178

  • IBU-DC Phosphoramidite
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    IBU-DC Phosphoramidite

    CAS:
    <p>IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.</p>
    Formula:C43H54N5O8P
    Color and Shape:Solid
    Molecular weight:799.906

    Ref: TM-T38496

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    Ribonuclease T1

    CAS:
    <p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>
    Color and Shape:Solid

    Ref: TM-T73609

  • Uridine triphosphate 13C9,15N2 sodium
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    Uridine triphosphate 13C9,15N2 sodium

    CAS:
    <p>Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.</p>
    Formula:C9H1415N2NaO15P3
    Color and Shape:Solid
    Molecular weight:517.04

    Ref: TM-T36299

  • Thio-ITP
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    Thio-ITP

    CAS:
    <p>Thio-ITP (6-Thioinosine 5'-triphosphate) inhibits RNA polymerases I &amp; II with Ki of 40.9 &amp; 38.0 μM.</p>
    Formula:C10H15N4O13P3S
    Color and Shape:Solid
    Molecular weight:524.23

    Ref: TM-T40359

  • ONX 0801 trisodium
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    ONX 0801 trisodium

    CAS:
    <p>ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.</p>
    Formula:C32H30N5Na3O10
    Color and Shape:Solid
    Molecular weight:713.58

    Ref: TM-T38490

  • (S)-DI-87
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    (S)-DI-87

    CAS:
    <p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>
    Formula:C23H30N6O3S2
    Purity:99.42%
    Color and Shape:Soild
    Molecular weight:502.65

    Ref: TM-T39550L

  • Xanthosine-5'-Triphosphate
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    Xanthosine-5'-Triphosphate

    CAS:
    <p>Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.</p>
    Formula:C10H15N4O15P3
    Color and Shape:Solid
    Molecular weight:524.164

    Ref: TM-T40714

  • Pseudorabies virus-IN-1
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    Pseudorabies virus-IN-1

    <p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>
    Formula:C27H23ClF2N4O2
    Color and Shape:Solid
    Molecular weight:508.947

    Ref: TM-T206101

  • 7-TFA-ap-7-Deaza-ddA
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    7-TFA-ap-7-Deaza-ddA

    CAS:
    <p>Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.</p>
    Formula:C16H16F3N5O3
    Color and Shape:Solid
    Molecular weight:383.331

    Ref: TM-T38534

  • SR15006
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    SR15006

    CAS:
    <p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>
    Formula:C16H20ClN3O4S
    Purity:99.87%
    Color and Shape:Soild
    Molecular weight:385.87

    Ref: TM-T60037

  • N6-Methyladenine
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    N6-Methyladenine

    CAS:
    <p>N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants.</p>
    Formula:C6H7N5
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:149.15

    Ref: TM-T36572

  • EFdA-TP
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    EFdA-TP

    CAS:
    <p>EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.</p>
    Formula:C12H15FN5O12P3
    Color and Shape:Solid
    Molecular weight:533.195

    Ref: TM-T41110

  • 5'-O-DMT-rU
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    5'-O-DMT-rU

    CAS:
    <p>5’-O-DMT-rU is a modified nucleoside and can be used to synthesize RNA.</p>
    Formula:C30H30N2O8
    Color and Shape:Solid
    Molecular weight:546.57

    Ref: TM-T37141

  • 5'-O-TBDMS-dG
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    5'-O-TBDMS-dG

    CAS:
    <p>5’-O-TBDMS-dG is a modified nucleoside. 5’-O-DMT-2’-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.</p>
    Formula:C16H27N5O4Si
    Color and Shape:Solid
    Molecular weight:381.50

    Ref: TM-T37144

  • 5'-O-DMT-2'-O-TBDMS-Ac-rC
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    5'-O-DMT-2'-O-TBDMS-Ac-rC

    CAS:
    <p>5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C38H47N3O8Si
    Color and Shape:Solid
    Molecular weight:701.892

    Ref: TM-T37132

  • (+)-Glaucarubinone
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    (+)-Glaucarubinone

    <p>(+)-Glaucarubinone is a natural product that can be used as a reference standard.</p>
    Formula:C25H34O10
    Color and Shape:Solid
    Molecular weight:494.537

    Ref: TM-T126136

  • Cy5-dATP
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    Cy5-dATP

    <p>Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] .</p>
    Formula:C47H58N7O19P3S2
    Color and Shape:Solid
    Molecular weight:1182.05

    Ref: TM-T75384

  • 5'-O-TBDMS-N2-ibu-dG
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    5'-O-TBDMS-N2-ibu-dG

    CAS:
    <p>5'-O-TBDMS-N2-ibu-dG: a nucleoside derivative with strong anti-BVDV activity, useful in lead compound synthesis.</p>
    Formula:C20H33N5O5Si
    Color and Shape:Solid
    Molecular weight:451.59

    Ref: TM-T40949

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    Clofarabine-5'-diphosphate trisodium

    <p>Clofarabine-5'-diphosphatetrisodium (Clofarabine-DP trisodium) is the sodium salt form of Clofarabine-5'-diphosphate. As a metabolic product of Clofarabine, it results from phosphorylation by deoxycytidine kinase (dCK). Clofarabine-5'-diphosphate trisodium can undergo further phosphorylation to form Clofarabine-5'-triphosphate, demonstrating cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>
    Formula:C10H10ClFN5Na3O9P2
    Color and Shape:Solid
    Molecular weight:529.58

    Ref: TM-T203582