DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 802 products of "DNA/RNA Synthesis"
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Nuclease S1
CAS:Nuclease S1 breaks down ssDNA and RNA, trims protruding ends of dsDNA.Color and Shape:SolidRAD51-IN-3
CAS:RAD51-IN-3 is a Rad51 inhibitor.Formula:C31H41N5O5S2Color and Shape:SolidMolecular weight:627.82N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
CAS:N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].
Formula:C21H35N12O17P3Color and Shape:SolidMolecular weight:820.497-TFA-ap-7-Deaza-ddA
CAS:Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.Formula:C16H16F3N5O3Color and Shape:SolidMolecular weight:383.331Guanosine 5'-triphosphate trisodium salt hydrate
CAS:5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.Formula:C10H18N5NaO15P3Purity:98%Color and Shape:SolidMolecular weight:564.185Dezecapavir
CAS:Dezecapavir (example 4) acts as an effective inhibitor of viral replication, exhibiting an EC50 value of 0.025 nM in MT2 cells with a CC50 greater than 0.5 μM.Formula:C37H29ClF9N9O5SColor and Shape:SolidMolecular weight:918.19WRN inhibitor 10
WRN inhibitor 10 (Compound P24) is an inhibitor of the Werner helicase WRN, with an IC50 of 1.1 nM. It effectively inhibits the proliferation of SW48 cancer cells, with an IC50 of 39 nM. WRN inhibitor 10 exhibits favorable liver microsomal stability and membrane permeability, and demonstrates good pharmacokinetic properties in CD-1 mice.Formula:C31H29BrClN9O5SMolecular weight:753.08843DG1
DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressingFormula:C19H17N5O5SColor and Shape:SolidMolecular weight:427.43Phen-DC3 Trifluoromethanesulfonate
CAS:Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.Formula:C36H26F6N6O8S2Purity:98%Color and Shape:SolidMolecular weight:848.752'-(2-Nitrobenzyl)-ATP trisodium
2'-(2-Nitrobenzyl)-ATP trisodium is an rATP analogue that acts as a transcription terminator. It inhibits T7 RNA polymerase from continuing RNA chain extension.Formula:C17H18N6Na3O15P3Color and Shape:SolidMolecular weight:707.97361GS-443902 trisodium
CAS:GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.Formula:C12H16N5O13P3·xNaColor and Shape:SolidEmicoron
CAS:Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.Formula:C52H58N6O4Purity:98%Color and Shape:SolidMolecular weight:831.05Guanosine triphosphate
CAS:Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].Formula:C10H16N5O14P3Color and Shape:SolidMolecular weight:523.1816,16-dimethyl Prostaglandin A1
CAS:16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.Formula:C22H36O4Color and Shape:SolidMolecular weight:364.526DNA31
CAS:DNA31 is a potent RNA polymerase inhibitor.Formula:C48H58N4O13Purity:98%Color and Shape:SolidMolecular weight:898.99ddATP lithium
ddATP (lithium) (2',3'-Dideoxyadenosine 5'-triphosphate (lithium)) is an active metabolite of 2',3'-dideoxyinosine and acts as a chain extension inhibitor of DNA polymerase. It is employed in DNA sequencing using the Sanger method and is also used in studies related to viral infections.Color and Shape:Odour Solidwrwyar-NH2 TFA
wrwyar-NH2 (TFA) serves as the control peptide for wrwycr-NH2.Color and Shape:Odour Solid5-BrdUTP sodium salt
CAS:5-BrdUTP sodium salt is a TdT substrate that can be used to label the DNA double-strand breaks.Formula:C9H10BrN2Na4O14P3Purity:98%Color and Shape:SolidMolecular weight:634.97HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt
CAS:HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.Formula:C57H62N8O10SColor and Shape:SolidMolecular weight:1051.21PINT-87aa TFA
PINT-87aa TFA, an 87-aa peptide from LINC-PINT, binds PAF1c, blocking oncogene transcription and glioblastoma growth.Formula:C396H628N140O115S13·C2HF3O2Color and Shape:SolidMolecular weight:9721.055'-O-DMT-rI
CAS:5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].Formula:C31H30N4O7Color and Shape:SolidMolecular weight:570.595'-O-DMT-PAC-dA
CAS:5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].Formula:C39H37N5O7Color and Shape:SolidMolecular weight:687.74Lucanthone N-oxide
CAS:Lucanthone N-oxide is a bioactive chemical.Formula:C20H24N2O2SColor and Shape:SolidMolecular weight:356.48Uridine triphosphate 13C9,15N2 sodium
CAS:Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.Formula:C9H1415N2NaO15P3Color and Shape:SolidMolecular weight:517.045'-O-DMT-N4-Bz-2'-F-dC
CAS:5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.Formula:C37H34FN3O7Color and Shape:SolidMolecular weight:651.68Ac-dA Phosphoramidite
CAS:Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.Formula:C42H50N7O7PColor and Shape:SolidMolecular weight:795.8785'-O-TBDMS-dU
CAS:5'-O-TBDMS-dU can be used in the synthesis of oligoribonucleotides.Formula:C15H26N2O5SiColor and Shape:SolidMolecular weight:342.46712R-LOX-IN-2
CAS:12R-LOX-IN-2 is a 12R-LOX inhibitor that inhibits the hyperproliferation of psoriatic cells and can be used in the study of psoriasis and other skin diseases.Formula:C19H13NOPurity:99.92%Color and Shape:SolidMolecular weight:271.315-O-TBDMS-N4-Benzoyl-2-deoxycytidine
CAS:5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.Formula:C22H31N3O5SiColor and Shape:SolidMolecular weight:445.58Tetrapeptide
CAS:Tetrapeptide, an α-MSH analogue, stimulates melanin production and mitigates DNA damage by attenuating reactive oxidative species generation and augmenting DNAFormula:C32H40N10O5Purity:98%Color and Shape:SolidMolecular weight:644.727-TFA-ap-7-Deaza-ddG
CAS:Compound 19d, a nucleotide derivative, is used to make thiotriphosphate dye terminators for DNA sequencing.Formula:C16H16F3N5O4Color and Shape:SolidMolecular weight:399.335'-O-TBDMS-dT
CAS:5’-O-TBDMS-dT is a nucleoside with protective and modification effects.Formula:C16H28N2O5SiColor and Shape:SolidMolecular weight:356.495'-O-DMT-2'-O-TBDMS-Bz-rC
CAS:5'-O-DMT-2'-O-TBDMS-Bz-rC, a modified nucleoside, is utilized in the synthesis of DNA or RNA.Formula:C43H49N3O8SiColor and Shape:SolidMolecular weight:763.95SCR7
CAS:SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).Formula:C18H14N4OSPurity:98%Color and Shape:SolidMolecular weight:334.4m7GpppGmpG
CAS:m7GpppGmpG, a trinucleotide 5′ cap analog, exhibits capping efficiencies of 86% for the RNAs obtained [1].Formula:C32H43N15O25P4Color and Shape:SolidMolecular weight:1161.66BRC4 peptide
BRC4 peptide, a specific segment of the BRCA2 protein, interacts with the RAD51 protein to assist in repairing broken DNA strands. It is useful in studying DNA repair mechanisms and the development of cancer.Formula:C178H296N48O53Molecular weight:3954.194247-Deazaxanthine
CAS:7-Deazaxanthine (7DX) is an inhibitor of thymidine phosphorylase (TPase) and reduces TPase activity in a concentration-dependent manner, with an IC50 value of 40 μM. Additionally, 7-Deazaxanthine exhibits significant anti-angiogenic properties.Formula:C6H5N3O2Color and Shape:SolidMolecular weight:151.12Polynucleotide kinase
CAS:Polynucleotide Kinase is a DNA repair enzyme. It exhibits 5'-kinase activity by catalyzing the transfer of phosphate from ATP to the 5'-hydroxyl (OH) end, and also shows 3'-phosphatase activity by converting the 3'-phosphate end into a 3'-OH end.5-Azacytidine 5′-triphosphate sodium
5-Azacytidine 5'-triphosphate sodium, a cytidine analog, selectively inhibits the incorporation of [3 H]CTP into RNA by DNA-dependent RNA polymerase, withoutColor and Shape:Odour Solid5'-O-DMT-2'-O-TBDMS-Ac-rC
CAS:5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.Formula:C38H47N3O8SiColor and Shape:SolidMolecular weight:701.892DMT-dG(ib) Phosphoramidite
CAS:DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.Formula:C44H54N7O8PPurity:99.21%Color and Shape:SolidMolecular weight:839.92EFdA-TP
CAS:EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.Formula:C12H15FN5O12P3Color and Shape:SolidMolecular weight:533.1953,4,6-Trichlorocatechol
CAS:TCC, a metabolite from Aroclor-1254 induced rats' livers, forms due to industrial pollutants.Formula:C6H3Cl3O2Color and Shape:SolidMolecular weight:213.445-Iminodaunorubicin
CAS:5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.Formula:C27H30N2O9Color and Shape:SolidMolecular weight:526.54PRV-IN-1
PRV-IN-1 (compound c14) demonstrates significant antiviral activity against pseudorabies virus (PRV) with an EC50 of 14 pM and a CC50 of 343.7 μM. It effectively inhibits the replication of PRV.Formula:C20H28N4O3Color and Shape:SolidMolecular weight:372.461Pseudorabies virus-IN-1
Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.Formula:C27H23ClF2N4O2Color and Shape:SolidMolecular weight:508.947Zelavespib HCl
CAS:PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT.Formula:C18H22ClIN6O2SPurity:99.45%Color and Shape:SoildMolecular weight:548.83FF-10502
CAS:FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.Formula:C9H12FN3O3SColor and Shape:SolidMolecular weight:261.27Xanthosine-5'-Triphosphate
CAS:Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.Formula:C10H15N4O15P3Color and Shape:SolidMolecular weight:524.164WRN inhibitor 18
CAS:WRN inhibitor 18 (compound 306) is an orally active inhibitor of WRN with demonstrated anticancer activity in vivo.Formula:C35H35F6N5O5SColor and Shape:SolidMolecular weight:751.74
