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DNA/RNA Synthesis

DNA/RNA Synthesis

Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.

Found 706 products of "DNA/RNA Synthesis"

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  • Lomibuvir
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    Lomibuvir

    CAS:
    <p>Lomibuvir (VCH-222, VX-222) is an allosteric inhibitor of HCV NS5B with Kd 17 nM, blocks RNA elongation, EC50 5.2 nM for 1b/Con1.</p>
    Formula:C25H35NO4S
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:445.61

    Ref: TM-T6729

  • Adafosbuvir
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    Adafosbuvir

    CAS:
    <p>Adafosbuvir has antiviral activity.</p>
    Formula:C22H29FN3O10P
    Color and Shape:Solid
    Molecular weight:545.457

    Ref: TM-T26560

  • PCNA-IN-1
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    PCNA-IN-1

    CAS:
    <p>PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.</p>
    Formula:C19H18I3NO3
    Color and Shape:Solid
    Molecular weight:689.065

    Ref: TM-T204170

  • TREX1-IN-4
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    TREX1-IN-4

    CAS:
    <p>TREX1-IN-4 (Compound 96) is an inhibitor of TREX1 and TREX2, exhibiting an IC50 of less than 0.1 μM for TREX1 and an IC50 of less than 1 μM for TREX2. It has an EC50 ranging from 0.1 to 10 μM in HCT116 cells. TREX1-IN-4 is applicable for research in the field of cancer.</p>
    Formula:C24H19ClN6O4
    Color and Shape:Solid
    Molecular weight:490.898

    Ref: TM-T205208

  • DNA ligase-IN-2
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    DNA ligase-IN-2

    CAS:
    <p>DNA ligase-IN-2 (compound 2) acts as a potent LigA inhibitor, effectively hindering the DNA-independent spontaneous adenylation activity of full-length LigA and the truncated enzyme LigA:AD with an IC50 of 29 nM. It also significantly suppresses the in vitro growth of Staphylococcus aureus, showing MIC values of 1 μg/mL for S. aureus ATCC 29213 and S. aureus ATCC 700699, while the MIC for Escherichia coli (E. coli) ATCC 25922 is &gt;64 μg/mL.</p>
    Formula:C13H8FN3O3
    Color and Shape:Solid
    Molecular weight:273.219

    Ref: TM-T204415

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    4,5'-Dimethylangelicin-NHS

    <p>NHS-modified coumarin, 4,5'-Dimethylangelicin-NHS, shows photochemical activity &amp; photosensitivity.</p>
    Formula:C21H19NO7S
    Color and Shape:Solid
    Molecular weight:429.44

    Ref: TM-T62365

  • HPH-15
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    HPH-15

    CAS:
    <p>HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.</p>
    Formula:C19H31N3S4
    Color and Shape:Solid
    Molecular weight:429.73

    Ref: TM-T205327

  • (E)-Antiviral agent 67
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    (E)-Antiviral agent 67

    CAS:
    <p>(E)-Antiviral agent 67 (compound PC6) is a pyrazolone-based antiviral compound that exhibits inhibitory activity against RNA-dependent RNA polymerase.</p>
    Formula:C19H19N3O
    Color and Shape:Solid
    Molecular weight:305.374

    Ref: TM-T206106

  • RAD51-IN-5
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    RAD51-IN-5

    CAS:
    <p>RAD51-IN-5 blocks RAD51; may aid mitochondrial disorder research. (WO2021164746A1, cmpd 3)</p>
    Formula:C26H38N4O5S2
    Color and Shape:Solid
    Molecular weight:550.73

    Ref: TM-T63892

  • EFdA-TP tetrasodium
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    EFdA-TP tetrasodium

    CAS:
    <p>EFdA-TP tetrasodium is a potent HIV-1 inhibitor that blocks DNA synthesis as an ICT or DCT.</p>
    Formula:C12H11FN5Na4O12P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:621.12

    Ref: TM-T72461

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    ddCTP trisodium

    <p>ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.</p>
    Formula:C9H13N3Na3O12P3
    Color and Shape:Solid
    Molecular weight:517.1

    Ref: TM-T63602

  • TREX1-IN-3
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    TREX1-IN-3

    CAS:
    <p>TREX1-IN-3 (Compound 95) is an inhibitor of TREX1 and TREX2, with an IC50 of less than 0.1 μM for TREX1 and less than 1 μM for TREX2, as well as an EC50 of less than 1 μM for HCT116 cells. It is applicable for research in the field of cancer.</p>
    Formula:C24H19ClN6O4
    Color and Shape:Solid
    Molecular weight:490.898

    Ref: TM-T205254

  • DHX9-IN-9
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    DHX9-IN-9

    CAS:
    <p>DHX9-IN-9 (509) acts as an inhibitor of the RNA helicase DHX9, demonstrating an EC50 of 0.0177 μM in DHX9 cellular target engagement, primarily utilized in cancer research [1].</p>
    Formula:C21H21ClFN5O3S2
    Color and Shape:Solid
    Molecular weight:510

    Ref: TM-T86205

  • KWR095
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    KWR095

    CAS:
    <p>KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.</p>
    Formula:C33H31ClF3N9O4
    Color and Shape:Solid
    Molecular weight:710.105

    Ref: TM-T205595

  • NSC 641396
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    NSC 641396

    CAS:
    <p>NSC 641396 is a ribonucleotide reductase (RNR) inhibitor with an IC50 value of 1.2 μM. Additionally, it acts as an inhibitor of protein arginine N-methyltransferase 9 (PRMT9) and exhibits antitumor properties.</p>
    Formula:C18H13NO3
    Color and Shape:Solid
    Molecular weight:291.301

    Ref: TM-T204449

  • Metesind Glucuronate
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    Metesind Glucuronate

    CAS:
    <p>Metesind Glucuronate is an antineoplastic. It also is a specific thymidylate synthase inhibitor.</p>
    Formula:C29H34N4O10S
    Color and Shape:Solid
    Molecular weight:630.67

    Ref: TM-T24454

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    Antitumor agent-74

    <p>Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.</p>
    Formula:C26H23FN6
    Color and Shape:Solid
    Molecular weight:438.5

    Ref: TM-T62509

  • WRN inhibitor 13
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    WRN inhibitor 13

    CAS:
    <p>WRN inhibitor 13 is an inhibitor of the WRN helicase with a pIC50 value ranging from 6 to 7.</p>
    Formula:C16H20N2O5S
    Color and Shape:Solid
    Molecular weight:352.405

    Ref: TM-T204389

  • DNA polymerase-IN-6
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    DNA polymerase-IN-6

    CAS:
    <p>DNA polymerase-IN-6 (Compound 27) exhibits inhibitory activity against DNA polymerase, with EC50 values of 0.33 µM for HCMV, 1.9 µM for HSV-1, 0.76 µM for HSV-2, and 0.066 µM for EBV.</p>
    Formula:C26H28ClFN8O4
    Color and Shape:Solid
    Molecular weight:571.003

    Ref: TM-T204284

  • 5-Iminodaunorubicin hydrochloride
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    5-Iminodaunorubicin hydrochloride

    CAS:
    <p>5-Iminodaunorubicin HCl: quinone-modified anthracycline with antitumor properties, induces DNA breaks in cancer cells.</p>
    Formula:C27H31ClN2O9
    Color and Shape:Solid
    Molecular weight:563.00

    Ref: TM-T72115