Antibiotic

<p>Sulfadiazine, a short-acting sulfonamide, blocks bacterial folic acid synthesis; used with pyrimethamine to treat toxoplasmosis in AIDS, newborns.</p>

<p>SDH-IN-19 (compound A13) is a fungicide effective against Rhizoctonia solani, with an EC50 value of 0.83 μg/mL. It is utilized in agricultural research for fungal resistance in crops.</p>

<p>(5S)-Neosamine C, an aminocyclic alcohol antibiotic derived from microbial secondary metabolites, possesses a cyclized structure and is utilized in the biosynthesis of Neomycins.</p>

<p>Cephalosporinase, bacillus, are enzymes produced by Bacillus; these enzymes inactivate and degrade the effectiveness of cephalosporin antibiotics. Cephalosporins are a class of β-lactam antibiotics widely used to treat bacterial infections [1].</p>

<p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>

<p>Cefotiam hydrochloride is a third-gen cephalosporin that disrupts bacterial cell wall synthesis by inhibiting PBPs.</p>

<p>Lincomycin hydrochloride (U10149A) is a lincosamide antibiotic identified in S.lincolnensis with activity against gram-positive cocci and anaerobic bacteria.</p>

<p>Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks NF-κB by preserving IκB.</p>

<p>Protorubradirin is an antibiotic that can be isolated from the non-pigmented Streptomyces achromogenes var. rubradiris alongside Rubradirin. It exhibits inhibitory activity against HIV reverse transcriptase. In vitro studies show that Protorubradirin also inhibits strains of Staphylococcus aureus and Streptococcus. In infected mice, subcutaneous administration of Protorubradirin demonstrates in vivo efficacy against antibiotic-resistant Staphylococcus aureus strains. However, oral administration may significantly reduce its activity compared to Rubradirin, possibly due to its C-nitroso sugar decomposing more rapidly in acidic gastric conditions.</p>

<p>BU-2313 A is a new antibiotic complex. It also active against anaerobes.</p>

<p>Mycinamicin I is a macrolide antibiotic.</p>

<p>Dactylarin: cytotoxic antibiotic from Dactylaria lutea, interacts with thiols, inhibits glycolytic enzymes.</p>

<p>Kijimicin is a polyether antibiotic and human immunodeficiency virus inhibitor in acutely and chronically infected cells.</p>

<p>Cefuzonam sodium: second-gen cephalosporin, effective against Staph aureus where third-gen fails.</p>

<p>Dehydrogriseofulvin is a natural product that can be used as a reference standard. The CAS number of Dehydrogriseofulvin is 3573-90-8.</p>

<p>AB023b is an antibiotic with antifungal properties.</p>

<p>Altromycin C is a new pluramycin-like antibiotic.</p>

<p>Lincosamine is a lincosamide antibiotic produced by Streptomyces lincolnensis.</p>

<p>AB023a is an antibiotic with antifungal properties.</p>

<p>Leucinostatin B is a peptide antibiotic from Paecilomyces lilacinus A-267.</p>