HIV Protease
HIV Protease inhibitors are a class of antiretroviral drugs that specifically target the protease enzyme of the Human Immunodeficiency Virus (HIV). By inhibiting this enzyme, these compounds prevent the virus from processing its polyproteins into mature, functional proteins, thereby blocking the production of new infectious virions. HIV Protease inhibitors are a cornerstone of highly active antiretroviral therapy (HAART) used to manage HIV/AIDS. At CymitQuimica, we provide a variety of HIV Protease inhibitors to support your research in HIV treatment, drug resistance, and virology.
Found 474 products of "HIV Protease"
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HIV-1 inhibitor-14
<p>HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.</p>Formula:C29H32N6O4SColor and Shape:SolidMolecular weight:560.67ZK-316
CAS:ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 range of 0.99 to 75.1 nM. It is applicable for HIV research.Formula:C27H22D6N6O3S2Color and Shape:SolidMolecular weight:554.72(S)-Batylalcohol
CAS:<p>(S)-Batylalcohol (1-O-Octadecyl-sn-glycerol) is an analogue of phosphonoformic acid (PFA) and demonstrates higher in vitro antiviral activity against human immunodeficiency virus type 1 (HIV-1) compared to PFA. This compound is applicable in antiretroviral research.</p>Formula:C21H44O3Color and Shape:SolidMolecular weight:344.572PD 134922
CAS:PD 134922 is a HIV-1 protease inhibitors. Inactivation of the protease prevents infectious virion formation.Formula:C37H61N5O7SPurity:98%Color and Shape:SolidMolecular weight:719.97MIV-150
CAS:MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).Formula:C19H17FN4O3Purity:98%Color and Shape:SolidMolecular weight:368.36HIV-1 inhibitor-41
<p>HIV-1 inhibitor-41 (B23): Oral non-nucleoside reverse transcriptase blocker, EC50 of 50 nM (E138K), 20.8 nM (WT), low hERG/CYP impact, non-toxic.</p>Formula:C16H15F2N3OSColor and Shape:SolidMolecular weight:335.374'-Ethynyl-2'-deoxyadenosine
CAS:4'-E-dA is a potent nucleoside RT inhibitor for drug-resistant HIV (EC50: 98 nM in MT-4 cells).Formula:C12H13N5O3Purity:98%Color and Shape:SolidMolecular weight:275.26DPC 684
CAS:DPC 684 is a potent and selective HIV-1 protease inhibitor with an IC90 of 5.7-40 nM and a Ki of 0.021 nM. It competitively inhibits HIV-1 protease, preventing viral polyprotein cleavage. Compared to cellular proteases, DPC 684 shows high selectivity for retroviral proteases. The compound exhibits low protein binding and offers broad-spectrum inhibition against various wild-type and mutant HIV-1 proteases, with an IC90 of 1.9-6.3 nM. DPC 684 is significant for HIV research.Formula:C35H48FN5O5SColor and Shape:SolidMolecular weight:669.85BRD-K98645985
CAS:BRD-K98645985: BAF inhibitor, binds ARID1A, reverses HIV-1 latency, EC50 ~2.37μM, alters nucleosome placement.Formula:C33H43N5O4Purity:98%Color and Shape:SolidMolecular weight:573.73ZLM-66
<p>ZLM-66: Doravirine analog, HIV-1 NNRTI inhibitor, IC50: 41nM, EC50: HIV-1 13nM, cIAP1 0.32nM; useful in AIDS research.</p>Color and Shape:SolidGSK3739936
CAS:<p>GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.</p>Formula:C34H43FN2O4Color and Shape:SolidMolecular weight:562.71HIV-1 inhibitor-18
<p>HIV-1 inhibitor-18 blocks HIV-1 capsid, effective on NL4-3 strain (EC50: 5.14 μM), slightly toxic (MT-4CC50>9.51).</p>Formula:C27H31N3O6SColor and Shape:SolidMolecular weight:525.62Telinavir
CAS:Telinavir (SC-52151) is a potent and selective inhibitor of HIV protease. It effectively inhibits both HIV-1 and HIV-2, as well as lymphotropic, monocytotropic strains, and wild isolates of simian immunodeficiency viruses, with an EC50 of 26 ng/mL (43 nM). Telinavir shows high protein binding in human plasma and a low distribution rate in red blood cells.Formula:C33H44N6O5Color and Shape:SolidMolecular weight:604.74BMS-818251
CAS:BMS-818251 is a potent small-molecule inhibitor that targets HIV-1 entry, with an EC50 value of 0.019 nM. It exhibits over 10 times greater efficacy on the cross-subtype panels of the 208-HIV-1 strain compared to BMS-626529. BMS-818251 enhances potency through interactions with gp120 residues in the conserved β20-β21 hairpin.Formula:C29H26N6O5SColor and Shape:SolidMolecular weight:570.619HIV-1 inhibitor-13
<p>HIV-1 inhibitor-13: oral NNRTI, IC50=0.14μM for HIV-1 RT, effective on resistant strains (EC50=2.85-18nM).</p>Formula:C30H32N6O3Color and Shape:SolidMolecular weight:524.61L-697639
CAS:L-697639 inhibits of HIV-1 reverse transcriptase and HIV-1 replication.Formula:C18H21N3O2Color and Shape:SolidMolecular weight:311.38Gardiquimod hydrochloride
CAS:Gardiquimod (hydrochloride) is an imidazoquinoline class TLR7/8 agonist. It can inhibit HIV-1 infection in macrophages and activated peripheral blood mononuclear cells (PBMCs). At concentrations below 10 μM, Gardiquimod (hydrochloride) specifically activates TLR7.Formula:C17H24ClN5OColor and Shape:SolidMolecular weight:349.858NBD-10007
CAS:NBD-10007 is an inhibitor of HIV-1 entry.Formula:C20H25ClN4O3SPurity:98%Color and Shape:SolidMolecular weight:436.96Cyclotriazadisulfonamide
CAS:<p>Cyclotriazadisulfonamide (CADA) is a specific inhibitor of HIV entry that targets CD4 by preventing the co-translational translocation of human CD4 (huCD4) into the endoplasmic reticulum (ER) lumen through a signal peptide (SP)-dependent mechanism.</p>Formula:C31H39N3O4S2Color and Shape:SolidMolecular weight:581.79Aurothioglucose
CAS:<p>Aurothioglucose is a active-site TrxR1 inhibitor.</p>Formula:C6H11AuO5SPurity:98%Color and Shape:Yellow Crystals SolidMolecular weight:392.183-Deazaadenosine
CAS:3-Deazaadenosine, an inhibitor of S-adenosylhomocysteine hydrolase with a Ki of 3.9 μM, exhibits anti-inflammatory, anti-proliferative, and anti-HIV activity.Formula:C11H14N4O4Purity:98%Color and Shape:SolidMolecular weight:266.25BMS-378806
<p>BMS-378806 is an HIV inhibitor with EC50: 0.85-26.5nM for various strains.</p>Formula:C22H22N4O4Purity:98%Color and Shape:SolidMolecular weight:406.43Oxindole
CAS:<p>Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.</p>Formula:C8H7NOPurity:99.34%Color and Shape:Off-White Crystalline PowderMolecular weight:133.15HIV-1 integrase inhibitor
CAS:Hiv-1 integrase inhibitor is an effective anti-HIV drug.Formula:C11H9N3O4Purity:98%Color and Shape:SolidMolecular weight:247.21
