HIV Protease
HIV Protease inhibitors are a class of antiretroviral drugs that specifically target the protease enzyme of the Human Immunodeficiency Virus (HIV). By inhibiting this enzyme, these compounds prevent the virus from processing its polyproteins into mature, functional proteins, thereby blocking the production of new infectious virions. HIV Protease inhibitors are a cornerstone of highly active antiretroviral therapy (HAART) used to manage HIV/AIDS. At CymitQuimica, we provide a variety of HIV Protease inhibitors to support your research in HIV treatment, drug resistance, and virology.
Found 489 products of "HIV Protease"
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DPC 684
CAS:DPC 684 is a potent and selective HIV-1 protease inhibitor with an IC90 of 5.7-40 nM and a Ki of 0.021 nM. It competitively inhibits HIV-1 protease, preventing viral polyprotein cleavage. Compared to cellular proteases, DPC 684 shows high selectivity for retroviral proteases. The compound exhibits low protein binding and offers broad-spectrum inhibition against various wild-type and mutant HIV-1 proteases, with an IC90 of 1.9-6.3 nM. DPC 684 is significant for HIV research.Formula:C35H48FN5O5SColor and Shape:SolidMolecular weight:669.85Saphenamycin
CAS:<p>Saphenamycin is an antibiotic from a strain of Streptomyces.</p>Formula:C23H18N2O5Purity:98%Color and Shape:SolidMolecular weight:402.404'-Ethynyl-2'-deoxyadenosine
CAS:4'-E-dA is a potent nucleoside RT inhibitor for drug-resistant HIV (EC50: 98 nM in MT-4 cells).Formula:C12H13N5O3Purity:98%Color and Shape:SolidMolecular weight:275.26L 702007
CAS:<p>L 702007 is an inhibitor of HIV-1 reverse transcriptase.</p>Formula:C18H25N3O2Purity:98%Color and Shape:SolidMolecular weight:315.41HIV-IN-3
<p>HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.</p>Formula:C21H32ClN7O3Color and Shape:SolidMolecular weight:465.98HIV-1-IN-86
CAS:HIV-1-IN-86 (compound 6m) is an HIV-1 inhibitor with an EC50 of 0.77 μM, exhibiting antiviral activity.Formula:C20H17N3O7SColor and Shape:SolidMolecular weight:443.43HIV-1 inhibitor-13
<p>HIV-1 inhibitor-13: oral NNRTI, IC50=0.14μM for HIV-1 RT, effective on resistant strains (EC50=2.85-18nM).</p>Formula:C30H32N6O3Color and Shape:SolidMolecular weight:524.61HIV-1 inhibitor-14
<p>HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.</p>Formula:C29H32N6O4SColor and Shape:SolidMolecular weight:560.67HIV-1 inhibitor-8
HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.Formula:C25H21N5OSColor and Shape:SolidMolecular weight:439.53HIV-1 inhibitor-61
CAS:HIV-1 Inhibitor-61 (2c) serves as a potent inhibitor of HIV-1 reverse transcriptase, exhibiting an EC50 value of 0.07 nM in NL4-3 wt MT-4 cells [1].Formula:C24H24F2N2O2SColor and Shape:SolidMolecular weight:442.52Integrase-LEDGF/p75 allosteric inhibitor 1
CAS:Oral HIV-1 allosteric integrase inhibitor, blocks DNA integration, antiviral, potent against NL432 (EC50: 3.9 nM).Formula:C33H41NO6SColor and Shape:SolidMolecular weight:579.75HIV-1 inhibitor-17
HIV-1 inhibitor-18 blocks HIV-1 capsid, acts on NL4-3 strain (EC50: 2.57 μM), has low cytotoxicity (MT-4 CC50: >8.55).Formula:C32H32N4O5SColor and Shape:SolidMolecular weight:584.69NBD-14189
CAS:NBD-14189: Potent HIV-1 entry blocker, binds gp120, IC50: 89 nM, strong antiviral (EC50 <200 nM).Formula:C18H16F4N4O2SColor and Shape:SolidMolecular weight:428.40BRD-K98645985
CAS:BRD-K98645985: BAF inhibitor, binds ARID1A, reverses HIV-1 latency, EC50 ~2.37μM, alters nucleosome placement.Formula:C33H43N5O4Purity:98%Color and Shape:SolidMolecular weight:573.73ZK-316
CAS:ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 range of 0.99 to 75.1 nM. It is applicable for HIV research.Formula:C27H22D6N6O3S2Color and Shape:SolidMolecular weight:554.72BMIM-TFSI
CAS:<p>BMIM-TFSI (compound8) is an HIV-1 integrase inhibitor that effectively suppresses both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration process. It is applicable in HIV-1 research.</p>Formula:C10H15F6N3O4S2Color and Shape:SolidMolecular weight:419.364GS-9822
CAS:GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.Formula:C36H39ClN4O4SColor and Shape:SolidMolecular weight:659.24L-697639
CAS:L-697639 inhibits of HIV-1 reverse transcriptase and HIV-1 replication.Formula:C18H21N3O2Color and Shape:SolidMolecular weight:311.38Lamivudine, (+/-)-trans-
CAS:<p>Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.</p>Formula:C8H11N3O3SPurity:98%Color and Shape:SolidMolecular weight:229.26HIV-1 inhibitor-40
HIV-1 inhibitor-40 (4ab) is a potent NNRTI (EC50: 1.9 nM), non-toxic in vivo, and a sensitive CYP inhibitor.Formula:C25H18N6O2Color and Shape:SolidMolecular weight:434.45Telinavir
CAS:Telinavir (SC-52151) is a potent and selective inhibitor of HIV protease. It effectively inhibits both HIV-1 and HIV-2, as well as lymphotropic, monocytotropic strains, and wild isolates of simian immunodeficiency viruses, with an EC50 of 26 ng/mL (43 nM). Telinavir shows high protein binding in human plasma and a low distribution rate in red blood cells.Formula:C33H44N6O5Color and Shape:SolidMolecular weight:604.74GSK3739936
CAS:<p>GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.</p>Formula:C34H43FN2O4Color and Shape:SolidMolecular weight:562.71Gardiquimod hydrochloride
CAS:Gardiquimod (hydrochloride) is an imidazoquinoline class TLR7/8 agonist. It can inhibit HIV-1 infection in macrophages and activated peripheral blood mononuclear cells (PBMCs). At concentrations below 10 μM, Gardiquimod (hydrochloride) specifically activates TLR7.Formula:C17H24ClN5OColor and Shape:SolidMolecular weight:349.858BMS-818251
CAS:BMS-818251 is a potent small-molecule inhibitor that targets HIV-1 entry, with an EC50 value of 0.019 nM. It exhibits over 10 times greater efficacy on the cross-subtype panels of the 208-HIV-1 strain compared to BMS-626529. BMS-818251 enhances potency through interactions with gp120 residues in the conserved β20-β21 hairpin.Formula:C29H26N6O5SColor and Shape:SolidMolecular weight:570.619MIV-150
CAS:MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).Formula:C19H17FN4O3Purity:98%Color and Shape:SolidMolecular weight:368.36Lentiginosine
CAS:Lentiginosine is a selective amyloglucosidase inhibitor.Formula:C8H15NO2Color and Shape:SolidMolecular weight:157.21Fipravirimat
CAS:Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.Formula:C43H67FN2O4SColor and Shape:SolidMolecular weight:727.07ZLM-66
<p>ZLM-66: Doravirine analog, HIV-1 NNRTI inhibitor, IC50: 41nM, EC50: HIV-1 13nM, cIAP1 0.32nM; useful in AIDS research.</p>Color and Shape:SolidPD 134922
CAS:PD 134922 is a HIV-1 protease inhibitors. Inactivation of the protease prevents infectious virion formation.Formula:C37H61N5O7SPurity:98%Color and Shape:SolidMolecular weight:719.97HIV-1 inhibitor-41
HIV-1 inhibitor-41 (B23): Oral non-nucleoside reverse transcriptase blocker, EC50 of 50 nM (E138K), 20.8 nM (WT), low hERG/CYP impact, non-toxic.Formula:C16H15F2N3OSColor and Shape:SolidMolecular weight:335.37A 76889
CAS:A 76889 is an inhibitor of HIV-1 protease.Formula:C44H58N8O6Purity:98%Color and Shape:SolidMolecular weight:794.98ATPase-IN-6
CAS:ATPase-IN-6 is an inhibitor of H+/K+-ATPase (ATPase) and a derivative of imidazopyridine. It exhibits significant antiviral activity against various viruses, such as HIV-1 and SARS-CoV-2. ATPase-IN-6 is applicable in antiviral infection research.Formula:C29H25N3O4SColor and Shape:SolidMolecular weight:511.59Emtricitabine triphosphate
CAS:Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.Formula:C8H13FN3O12P3SColor and Shape:SolidMolecular weight:487.19BI-2540
CAS:BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .Formula:C24H15ClF5NO5Color and Shape:SolidMolecular weight:527.83BMS-378806
<p>BMS-378806 is an HIV inhibitor with EC50: 0.85-26.5nM for various strains.</p>Formula:C22H22N4O4Purity:98%Color and Shape:SolidMolecular weight:406.433-Deazaadenosine
CAS:3-Deazaadenosine, an inhibitor of S-adenosylhomocysteine hydrolase with a Ki of 3.9 μM, exhibits anti-inflammatory, anti-proliferative, and anti-HIV activity.Formula:C11H14N4O4Purity:98%Color and Shape:SolidMolecular weight:266.25Aurothioglucose
CAS:Aurothioglucose is a active-site TrxR1 inhibitor.Formula:C6H11AuO5SPurity:98%Color and Shape:Yellow Crystals SolidMolecular weight:392.18Oxindole
CAS:<p>Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.</p>Formula:C8H7NOPurity:99.34%Color and Shape:Off-White Crystalline PowderMolecular weight:133.15HIV-1 integrase inhibitor
CAS:Hiv-1 integrase inhibitor is an effective anti-HIV drug.Formula:C11H9N3O4Purity:98%Color and Shape:SolidMolecular weight:247.21
