HIV Protease
HIV Protease inhibitors are a class of antiretroviral drugs that specifically target the protease enzyme of the Human Immunodeficiency Virus (HIV). By inhibiting this enzyme, these compounds prevent the virus from processing its polyproteins into mature, functional proteins, thereby blocking the production of new infectious virions. HIV Protease inhibitors are a cornerstone of highly active antiretroviral therapy (HAART) used to manage HIV/AIDS. At CymitQuimica, we provide a variety of HIV Protease inhibitors to support your research in HIV treatment, drug resistance, and virology.
Found 506 products of "HIV Protease"
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GSK3532795
CAS:GSK3532795: potent oral HIV-1 maturation inhibitor; EC50: 1.9-13 nM for various strains.Formula:C42H62N2O4SPurity:98%Color and Shape:SolidMolecular weight:691.027-Deaza-2',3'-dideoxyguanosine
CAS:7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2′,3′-dideoxynucleoside 5′-triphosphate that inhibits HIV-1 reverse transcriptase with a Ki of 25 nM [1].Formula:C11H14N4O3Color and Shape:SolidMolecular weight:250.25HIV-1 integrase inhibitor 3
CAS:HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 2.7 nM).Formula:C21H22F2N4O4Purity:98%Color and Shape:SolidMolecular weight:432.42I-XW-053
CAS:I-XW-053 is an inhibitor of capsid targeted HIV-1 replication using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-Formula:C22H16N2O2Purity:99.05%Color and Shape:SolidMolecular weight:340.37XZ426
CAS:XZ426 is a potent integrase strand transfer inhibitor with anti- HIV activity .Formula:C22H24F2N4O4Color and Shape:SolidMolecular weight:446.45BILR-355
CAS:BILR-355 is a reverse transcriptase inhibitor.Formula:C25H23N5O3Purity:98%Color and Shape:SolidMolecular weight:441.48U 89360E
CAS:U 89360E is a peptidic inhibitor.Formula:C28H52N8O6Purity:98%Color and Shape:SolidMolecular weight:596.7612-Bromododecanoic Acid
CAS:12-Bromododecanoic acid, a halogenated derivative of lauric acid, serves in the synthesis of clickable myristic acid derivatives and functions as a model fatty acid ligand for elucidating the X-ray crystal structure of bovine β-lactoglobulin-ligand complexes. This compound, at a concentration of 10 µg/ml, has been shown to diminish virion DNA in the culture supernatant of primary hepatocytes from a duckling model of hepatitis B virus (HBV) infection and exhibits inhibitory activity against HIV replication in CEM-SS T cells with an EC50 value of 38 µM.Formula:C12H23BrO2Color and Shape:SolidMolecular weight:279.218U 104489
CAS:U 104489 (PNU-104489) is a novel specific inhibitor of human immunodeficiency virus 1 (HIV-1), showing effective activity against BHA-P-resistant HIV-1MF.Formula:C26H36N6O3SColor and Shape:SolidMolecular weight:512.67HIV-1 inhibitor-10
CAS:HIV-1 inhibitor-10 is a nanomolar HIV-1 maturation inhibitor.Formula:C39H54O6Color and Shape:SolidMolecular weight:618.84BMS-561390
CAS:BMS-561390, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C14H12ClF3N2OColor and Shape:SolidMolecular weight:316.71A 77003
CAS:A 77003 is a HIV-1 protease inhibitor. A77003 impairs HIV-1 protease-mediated Gag processing.Formula:C44H58N8O6Color and Shape:SolidMolecular weight:794.98WRNA10
CAS:WRNA10 is a potent binding agent for HIV-1TAR RNA (IC50: 10 μM, CC50: 40 μM).Formula:C25H32N4O4Color and Shape:SolidMolecular weight:452.55Ro 31-8588
CAS:Talviraline (HBY 097) inhibits HIV-1 replication and reduces cell death in various cells and immune cells.Formula:C33H56N4O5Color and Shape:SolidMolecular weight:588.82L-689502
CAS:L-689502 is a potent HIV-l protease inhibitor (IC50: 1 nM).Formula:C39H51N3O7Purity:98%Color and Shape:SolidMolecular weight:673.84Ulonivirine
CAS:Ulonivirine is an orally active non-nucleoside reverse transcriptase inhibitor that exhibits high antiviral activity and can be used to study HIV-1 infection.Formula:C18H8ClF6N5O3Color and Shape:SolidMolecular weight:491.73DGKα-IN-8
CAS:DGKα-IN-8 (Example 51) is a potent diacylglycerol kinase alpha (DGKα) inhibitor, exhibiting an IC50 of 22.491 nM and an EC50 of 0.256 nM.Formula:C23H19ClF3N5OColor and Shape:SolidMolecular weight:473.88Reverse transcriptase-IN-1
CAS:Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7Formula:C25H17N7O2Purity:99.61%Color and Shape:SolidMolecular weight:447.45Ref: TM-T12715
1mg60.00€5mg124.00€10mg173.00€25mg295.00€50mg425.00€100mg583.00€200mg790.00€1mL*10mM (DMSO)136.00€Teropavimab
CAS:Teropavimab (3BNC117-LS), an antibody, is utilized in the research of HIV infection [1].Color and Shape:LiquidBavtavirine
CAS:Bavtavirine is a non-nucleoside reverse HIV-1 transcriptase inhibitor (NNRTIs),inhibits HIV replication by preventing the transcription of viral RNA into DNA.Formula:C26H20N6Purity:97.2%Color and Shape:SolidMolecular weight:416.48BMS-955176 HCl
CAS:GSK-3532795: a broader-spectrum HIV-1 maturation inhibitor than bevirimat, effective in vitro and clinically.Formula:C42H62N2O4SColor and Shape:SolidMolecular weight:727.486Azt-pmap
CAS:AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1].Formula:C20H25N6O8PPurity:98%Color and Shape:SolidMolecular weight:508.42Berlopentin
CAS:Berlopentin is splenopentin analog used to treat HIV-positive patients. It also has immunostimulatory properties.Formula:C35H55N9O11Color and Shape:SolidMolecular weight:777.86Capravirine
CAS:Capravirine, a non-nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C20H20Cl2N4O2SPurity:98%Color and Shape:SolidMolecular weight:451.37HIV-1 protease-IN-11
CAS:HIV-1 protease-IN-11 (compound 34a), an HIV-1 protease inhibitor, demonstrates potent inhibition with an IC50 of 0.41 nM and maintains substantial efficacyFormula:C26H37N3O5SPurity:98%Color and Shape:SolidMolecular weight:503.65Indinavir, threo-
CAS:Indinavir, threo- is a protease inhibitor utilized as a component of highly active antiretroviral treatment to HIV/AIDS.Formula:C36H47N5O4Purity:98%Color and Shape:SolidMolecular weight:613.79HIV-1 protease-IN-8
CAS:HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM.Formula:C25H35N3O5SPurity:98%Color and Shape:SolidMolecular weight:489.63A 74704
CAS:A 74704 is a pseudo C2-symmetric inhibitor of HIV-1 protease and its diester analog.Formula:C43H52N4O7Purity:98%Color and Shape:SolidMolecular weight:736.9Droxinavir HCl
CAS:Droxinavir HCl is an antiviral agent and HIV protease inhibitor.Formula:C29H52ClN5O4Purity:98%Color and Shape:SolidMolecular weight:570.22HIV-1 protease-IN-7
CAS:HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].Formula:C68H104N10O12SPurity:98%Color and Shape:SolidMolecular weight:1285.68HIV-1 protease-IN-12
CAS:HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-Formula:C25H35N3O5SPurity:98%Color and Shape:SolidMolecular weight:489.63HIV-1 protease-IN-9
CAS:HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and aFormula:C37H41N7O4SPurity:98%Color and Shape:SolidMolecular weight:679.83Palinavir
CAS:Palinavir is an antiviral, it inhibits HIV-1 protease.Formula:C41H52N6O5Purity:98%Color and Shape:SolidMolecular weight:708.89PYR01
CAS:PYR01 is a potent nonnucleoside reverse transcriptase inhibitor of HIV-1 and concurrently acts as a targeted activator to eliminate cells expressing HIV-1 [1].Formula:C21H13F7N4O3Color and Shape:SolidMolecular weight:502.343′-Deoxy Thymidine
CAS:3′-Deoxy Thymidine is a nucleoside analog of thymidine with antiviral activity. 3′-Deoxy Thymidine inhibit HIV replication in peripheral blood mononuclear cells (EC50 = 0.17 µM). 3′-Deoxy Thymidine also decreases plaque formation in CV-1 cells infected with HSV-1 at micromolar concentrations. These properties support the use of 3′-Deoxy Thymidine in antiviral mechanism studies and nucleoside analog evaluation.Formula:C10H14N2O4Purity:99.89%Color and Shape:SolidMolecular weight:226.23DMP 323
CAS:DMP 323 is a potent inhibitor of HIV-1 protease.Formula:C35H38N2O5Purity:98%Color and Shape:SolidMolecular weight:566.69KNI-272
CAS:Kynostatin-272 is a HIV protease inhibitor. KNI-272 blocked the maturation of viral particles.Formula:C33H41N5O6S2Color and Shape:SolidMolecular weight:667.84L 694746
CAS:L 694746 is an inhibitor of HIV-1 protease.Formula:C35H42N2O8Purity:98%Color and Shape:SolidMolecular weight:618.72R 87366
CAS:R 87366 is used as a water-soluble HIV protease inhibitor.Formula:C32H39N7O6Purity:98%Color and Shape:SolidMolecular weight:617.7PNU-103017
CAS:PNU-103017 is an inhibitor of HIV protease.Formula:C28H28N2O5SPurity:98%Color and Shape:SolidMolecular weight:504.6HIV-IN-8
CAS:HIV-IN-8 (Compound 9) acts as an HIV inhibitor, suppressing HIV replication with an effective concentration (EC50) of 13 μg/mL [1].Formula:C36H30O16Color and Shape:SolidMolecular weight:718.61L 687908
CAS:L 687908 is a potent inhibitor of hydroxyethylene-containing HIV protease.Formula:C40H51N5O5Purity:98%Color and Shape:SolidMolecular weight:681.86Rp-dGTPαS
CAS:Rp-dGTPαS, an enantiomer of the dNTPαS nucleotide, serves as the substrate for SAMHD1, a critical regulator of cellular dNTP levels that curtails the replication of viruses (HIV-1, etc.) in CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex facilitates the hydrolysis of Rp-dGQTPαS into 2'-deoxynucleosides and triphosphates [1].Formula:C10H16N5O12P3SColor and Shape:SolidMolecular weight:523.25Cgp 57813
CAS:CGP 57813 is a lipophilic compound, which can be used as an inhibitor of HIV-1 protease.Formula:C43H58N4O8Color and Shape:SolidMolecular weight:758.94NNRTIs-IN-1
CAS:NNRTIs-IN-1 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with notable anti-resistance efficacy, effectively inhibiting both the wild-typeFormula:C28H22N6O3Color and Shape:SolidMolecular weight:490.51HIV-1 inhibitor-3
CAS:HIV-1 inhibitor-3 is an HIV infection inhibitor.Formula:C9H10F2N2O5Purity:98%Color and Shape:SolidMolecular weight:264.18Hinokinin
CAS:Hinokinin (Cubebinolide), a bioactive lignan, exhibits a broad spectrum of pharmacological activities.Formula:C20H18O6Color and Shape:SolidMolecular weight:354.35SW106
CAS:SW106 blocks PTHR1 cAMP signaling, not affecting mutant PTHR1-T410P/H223R.Formula:C16H14F5NO2Color and Shape:SolidMolecular weight:347.28GSK3839919A
CAS:GSK3839919A is a potent allosteric inhibitor of HIV-1 integrase [1].Formula:C36H46ClN3O3Color and Shape:SolidMolecular weight:604.22Hydroxy Darunavir
CAS:Hydroxy darunavir, a metabolite of the HIV-1 protease inhibitor darunavir, is generated through isobutyl aliphatic hydroxylation of darunavir.Formula:C27H37N3O8SColor and Shape:SolidMolecular weight:563.66
