HIV Protease
HIV Protease inhibitors are a class of antiretroviral drugs that specifically target the protease enzyme of the Human Immunodeficiency Virus (HIV). By inhibiting this enzyme, these compounds prevent the virus from processing its polyproteins into mature, functional proteins, thereby blocking the production of new infectious virions. HIV Protease inhibitors are a cornerstone of highly active antiretroviral therapy (HAART) used to manage HIV/AIDS. At CymitQuimica, we provide a variety of HIV Protease inhibitors to support your research in HIV treatment, drug resistance, and virology.
Found 478 products for "HIV Protease".
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HIV-1 inhibitor-52
CAS:HIV-1 inhibitor-52: potent, broad-spectrum with EC50s 1.6-6.4 nM against various HIV-1 strains.Formula:C46H72FNO5SColor and Shape:SolidMolecular weight:770.13GSK3739936
CAS:GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.Formula:C34H43FN2O4Color and Shape:SolidMolecular weight:562.71BMIM-TFSI
CAS:BMIM-TFSI (compound8) is an HIV-1 integrase inhibitor that effectively suppresses both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration process. It is applicable in HIV-1 research.Formula:C10H15F6N3O4S2Color and Shape:SolidMolecular weight:419.364BRN3OMe
CAS:BRN3OMe is an effective inhibitor of HIV-1 reverse transcriptase (HIV-1 reverse transcriptase), showing potential for antiviral drug research.Formula:C7H13N3O4Color and Shape:SolidMolecular weight:203.196Lamivudine, (+/-)-trans-
CAS:Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.Formula:C8H11N3O3SPurity:98%Color and Shape:SolidMolecular weight:229.26HIV-1 inhibitor-44
HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).Formula:C23H26N2O4SColor and Shape:SolidMolecular weight:426.53HIV-1 inhibitor-18
HIV-1 inhibitor-18 blocks HIV-1 capsid, effective on NL4-3 strain (EC50: 5.14 μM), slightly toxic (MT-4CC50>9.51).Formula:C27H31N3O6SColor and Shape:SolidMolecular weight:525.62GS-9822
CAS:GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.Formula:C36H39ClN4O4SColor and Shape:SolidMolecular weight:659.24HIV-1 inhibitor-8
HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.Formula:C25H21N5OSColor and Shape:SolidMolecular weight:439.53Gardiquimod hydrochloride
CAS:Gardiquimod (hydrochloride) is an imidazoquinoline class TLR7/8 agonist. It can inhibit HIV-1 infection in macrophages and activated peripheral blood mononuclear cells (PBMCs). At concentrations below 10 μM, Gardiquimod (hydrochloride) specifically activates TLR7.Formula:C17H24ClN5OColor and Shape:SolidMolecular weight:349.858Desthiazolylmethyl ritonavir
CAS:Desthiazolylmethyl ritonavir is an alkaline-catalyzed degradation product of the HIV protease inhibitor Ritonavir.Formula:C33H43N5O4SColor and Shape:SolidMolecular weight:605.791HIV-1 protease-IN-6
HIV-1 protease-IN-6 (17d) strongly inhibits HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM) and effectively targets DRV-resistant mutants.Formula:C27H31FN2O6SColor and Shape:SolidMolecular weight:530.61HIV-1 inhibitor-82
CAS:HIV-1inhibitor-82 (Compound L14) is a small molecule inhibitor of HIV-1 entry with oral bioavailability, exhibiting an IC50 value of 0.39 μM. It holds potential for research in combating HIV-1 infection.Formula:C37H37ClN2O6S2Color and Shape:SolidMolecular weight:705.28HIV-1-IN-86
CAS:HIV-1-IN-86 (compound 6m) is an HIV-1 inhibitor with an EC50 of 0.77 μM, exhibiting antiviral activity.Formula:C20H17N3O7SColor and Shape:SolidMolecular weight:443.43HIV-1 inhibitor-13
HIV-1 inhibitor-13: oral NNRTI, IC50=0.14μM for HIV-1 RT, effective on resistant strains (EC50=2.85-18nM).Formula:C30H32N6O3Color and Shape:SolidMolecular weight:524.61BMS-818251
CAS:BMS-818251 is a potent small-molecule inhibitor that targets HIV-1 entry, with an EC50 value of 0.019 nM. It exhibits over 10 times greater efficacy on the cross-subtype panels of the 208-HIV-1 strain compared to BMS-626529. BMS-818251 enhances potency through interactions with gp120 residues in the conserved β20-β21 hairpin.Formula:C29H26N6O5SColor and Shape:SolidMolecular weight:570.619Fipravirimat
CAS:Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.Formula:C43H67FN2O4SColor and Shape:SolidMolecular weight:727.07ML67-33
CAS:ML67-33 selectively activates K2P channels; EC50: 36.3 μM (cell-free), 9.7 μM (HEK293). Reversible TREK-1 modulation.Formula:C18H17Cl2N5Purity:98%Color and Shape:SolidMolecular weight:374.27
