Antibacterial

Gepotidacin S enantiomer is an S enantionmer of gepotidacin.

Azidocillin, a semi-synthetic oral β-lactam antibiotic, treats various bacterial infections including osteitis and septicemia.

Maximin 15, an antimicrobial peptide originating from toad brain, exhibits activity against Staphylococcus aureus, Escherichia coli, and Bacillus subtilis, with

C12-rrw-NH2 (Compound Lip7) is an antimicrobial agent effective against Gram-positive bacteria, particularly demonstrating significant activity against Methicillin-resistant Staphylococcus aureus (MRSA). It induces bacterial cell death by depolarizing the bacterial cell membrane, disrupting membrane integrity, causing nucleic acid and protein leakage, and promoting the generation of Reactive Oxygen Species (ROS). C12-rrw-NH2 is applicable in research focused on developing highly stable antimicrobial peptides.

Dicloxacillin, a β-Lactam antibiotic, targets beta-lactamase bacteria like Staphylococcus aureus, defeating penicillin resistance.

Efflux pump-IN-3 inhibits AcrB, potentiates antibiotics, and is non-toxic to membranes and nematodes.

XT17 is an anthrone compound with broad-spectrum antibacterial activity, exerting its effects by disrupting the cell wall and inhibiting DNA synthesis. It demonstrates weak hemolytic activity, low cytotoxicity to mammalian cell lines, and a low rate of resistance development. Additionally, XT17 shows in vivo efficacy in a mouse corneal infection model induced by Staphylococcus aureus or Pseudomonas aeruginosa. Further docking studies confirm that XT17 forms a stable complex with bacterial gyrase. XT17 is suitable for research in the field of anti-infective agents.

Allolactose is a disaccharide used as an inducer of the lac operon in Escherichia coli and many other enteric bacteria.

β-Lactamase-IN-4 (WO2013149121A1, compound 708) is a potent β-lactamase inhibitor. It serves as a valuable tool in the investigation of bacterial infections.

Agent 38 from patent WO2015063714A1 (C) serves as an antibacterial for scientific study.

D13-9001, an antibiotic, inhibits AcrB and MexB with KDs of 1.15μM in E. coli and 3.57μM in P. aeruginosa.

Aurein 3.1 is an antibiotic antimicrobial peptide, whereas Aurein 2.6 demonstrates activity against Gram-positive bacteria, exhibiting minimum inhibitory

Ledaborbactam etzadroxil (VNRX-7145) is an orally active inhibitor of Ambler class A, C, and D β-lactamase enzymes.

GSK299423: Antibiotic possibly effective against bacteria with New Delhi metal-β-lactamase, targeting topoisomerases.

6-C-Methylquercetin-3,4'-dimethyl ether is a flavonol derivative extracted from Bauhinia thonningii Schum leaves, displaying antibacterial effects on Gram-

Desacetylcefotaxime, a Cefotaxime metabolite, has strong antimicrobial effects against various bacteria.

Picromycin is a macrolide antibiotic and PREP inhibitor effective against gram-positive bacteria, including mycobacteria.

Antibacterial agent 150 (compound 5g) exhibits potent activity against a wide range of bacteria, including both Gram-positive and Gram-negative species, with

Brilliant green: dye for silk/wool, inhibits mold, parasites, fungus, and kills Gram-positive bacteria.

LBM-415 is a peptide deformylase (PDF) inhibitor.