Antibacterial

Atrovenetin is an antibiotic found in Penicillium species (antibiotic). It exhibits inhibitory activity against Bacillus subtilis and Staphylococcus aureus. Atrovenetin is also a potent antioxidant.

Zelkovamycin, a cyclic peptide antibiotic, blocks X. oryzae, P. oryzae, S. aureus, A. laidlawii growth at 0.01-300 μg/ml concentration.

Razupenem (SMP-601, PTZ601), a broad-spectrum injectable carbapenem, counters antibiotic-resistant bacteria.

ROS inducer 8 (Compound 11g) acts as an inhibitor of glutathione (GSH) and promotes the accumulation of reactive oxygen species (ROS) in Enterococcus faecalis, exhibiting antibacterial properties. It is capable of disrupting biofilms and inhibiting S. aureus and E. faecalis with minimum inhibitory concentrations (MICs) of 8 μg/mL and 2 μg/mL, respectively, demonstrating a post-antibiotic effect. Additionally, ROS inducer 8 shows low hemolytic toxicity on sheep red blood cells with an HC50 greater than 1280 μg/mL.

Viomycin: tuberactinomycin antibiotic, halts prokaryotic protein synthesis and group I intron splicing, arrests bacterial ribosomes.

Xenopsin precursor fragment, an antimicrobial peptide, exhibits both antibacterial/antifungal activity at concentrations ranging from 10 to 500 μg/mL and anti-

Aurein 2.4, an antibiotic antimicrobial peptide, exhibits activity against Gram-positive bacteria [1] [2].

XT-2 peptide, an antimicrobial agent sourced from the skin secretions of Xenopus tropicalis, exhibits potent activity against E.

Quorum sensing-IN-10 (10p) is an antimicrobial adjuvant that significantly inhibits the virulence, biofilm formation, and motility of Pseudomonas aeruginosa, while exhibiting low toxicity. It is applicable for research related to drug-resistant Pseudomonas aeruginosa infections.

Saccharocarcin A, an antibiotic from S. aerocolonigenes, combats various bacteria and inhibits C. trachomatis at 0.5 μg/ml, non-toxic to McCoy cells.

NOSO-502: Bacterial translation inhibitor, active against Enterobacteriaceae, safe and effective antibacterial.

Mycothiol detoxifies, links foreign compounds, and acts as microbes' glutathione.

Choline Iodide has antibacterial activity against Leishmania panamensis and inhibitor of Acetylcholinesterase, degenerative neurological diseases.

Valclavam is a biochemical.

Altromycin E is a new pluramycin-like antibiotic.

Calcium lactate (Conclyte) fortifies juice with calcium and aids soybean sprout growth and phytic acid breakdown.

Rifamycin: Natural antibiotic; blocks prokaryotic RNA synthesis by halting RNA-polymerase.

cis-11-Methyl-2-dodecenoic acid: a QS signal, aids microbial communication, regulates virulence, biofilm in pathogens.

KPC-2-IN-1, a boronic acid KPC-2 inhibitor (Ki 0.032 μM), boosts cefotaxime against KPC-2 E. coli; tolerable in HEK-293 cells.