Antibacterial

Razupenem (SMP-601, PTZ601), a broad-spectrum injectable carbapenem, counters antibiotic-resistant bacteria.

Valclavam is a biochemical.

<p>Compound 1h (Antibacterial agent 108) is a potent antibacterial agent, demonstrating a minimum inhibitory concentration (MIC) of 3 μM against both MRSA and</p>

Apigravin, a potent antibacterial compound, demonstrates activity against Bacillus subtilis, exhibiting a minimum inhibitory concentration (MIC) value of 61 μM

Maximin 42 is an antimicrobial peptide with antibacterial activity against S.

<p>Astodrimer: large (~3-4 nm, ~16.5 kDa), negative dendrimer with broad-spectrum antiviral, virucidal, and antibacterial properties.</p>

<p>A-54556B: Natural ADEP antibiotic from S. hawaiiensis, combats Gram-positive and anaerobic bacteria, including penicillin-resistant S. aureus.</p>

Antitubercular agent-35 (42l) inhibits Mtb H37Rv (MIC 90=1.25 μg/mL) and M. Marinum (MIC 90=2 μg/mL), resists liver degradation, for TB research.

Antibacterialagent 119 (Compound 21 g) is a potential antibacterial agent effective against methicillin-resistant Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of less than 1 μg/mL against tested strains. It induces reactive oxygen species (ROS) generation and disrupts bacterial cell membranes, causing their rupture. Antibacterialagent 119 exhibits strong antimicrobial activity, low cytotoxicity, rapid bactericidal action, and favorable in vivo antibacterial efficacy.

Citromycetin, a fungal metabolite, has antibiotic effects on V. cholerae, S. flexneri, and S. aureus.

Antibacterialagent 189 (compound 3a) is a potent antibacterial agent with high binding affinity to the target proteins OMPA/exo-1,3-β-glucanase. It demonstrates effective antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Candida albicans, and Aspergillus flavus. Additionally, Antibacterialagent 189 exhibits strong binding affinity to the target proteins SMO and SUFU/GLI-1.

Pyrindamycin B is an antibiotic,and actives against gram-positive and gram-negative bacterias

<p>Vineomycin A1 (OS-4742 A1) is an antibiotic effective against Gram-positive bacteria, identified in *Streptomyces matensis* subsp. vineus. It has also demonstrated antitumor activity in mice and holds potential for research in skin fibrosis.</p>

<p>Antituberculosis agent-13 (Compound 11) demonstrates antituberculosis activity, effectively inhibiting both wild-type and mutant strains of Mycobacterium tuberculosis, with an IC50 range of 4-62.5 nM. Additionally, Antituberculosis agent-13 exhibits anti-leukemia properties, inhibiting MOLM-13 with an IC50 of 3.8 μM.</p>

Murrayanol is a useful organic compound for research related to life sciences and the catalog number is T125851.

<p>PR-39 TFA, a peptide, noncompetitively inhibits proteasomes, spurring angiogenesis and reducing inflammation and mouse myocardial infarct size.</p>

Psoracorylifol C is a useful organic compound for research related to life sciences and the catalog number is T124015.

<p>MRV03-070, acting as a biosynthetic precursor akin to precolibactin [1], is a colibactin-activating peptidase ClbP inhibitor with an inhibitory concentration (</p>

Hodgkinsine, a pyrrolidinoindoline alkaloid with analgesic properties, found in P. colorata, increases pain tolerance in mice at 5 mg/kg.

<p>Gemifloxacin is a fluoronaphthyridone with strong antibacterial effect.</p>