Antibacterial

Uvaretin demonstrates potent antibacterial activity against B. subtilis (EC50: 8.7 μM) and S. epidermidis (IC50: 7.9 μM).

XT17 is an anthrone compound with broad-spectrum antibacterial activity, exerting its effects by disrupting the cell wall and inhibiting DNA synthesis. It demonstrates weak hemolytic activity, low cytotoxicity to mammalian cell lines, and a low rate of resistance development. Additionally, XT17 shows in vivo efficacy in a mouse corneal infection model induced by Staphylococcus aureus or Pseudomonas aeruginosa. Further docking studies confirm that XT17 forms a stable complex with bacterial gyrase. XT17 is suitable for research in the field of anti-infective agents.

Retro-indolicidin, a synthetic analog of the cathelicidin-derived antimicrobial peptide-amide indolicidin, comprises a reversed 13-amino acid sequence isolated

Chartreusin sodium is a biochemical.

Leucanicidin: a macrolide from S. halstedii, toxic to L. separata larvae at 20 ppm; LD50: 0.23-0.42 µg/ml for some worms.

Melimine, a hybrid antimicrobial peptide derived from Melittin and Protamine, exhibits broad-spectrum activity against various microorganisms, including

Antibacterial agent 127 (Compound 23) is a potent antibacterial agent [1] .

Antibacterial agent 40 is an antibacterial agent.

Kalimantacin A: a potent antibiotic effective against MRSA and other staphylococci.

Farobin A, a natural compound, exhibits antibacterial, antioxidant, and anti-inflammatory properties. It is effective against Streptococcus mutans ATCC 25175 and Streptococcus sobrinus ATCC 33478. Additionally, Farobin A demonstrates anti-inflammatory activity by targeting cytokine IL-6 and TNF-α [1].

SCH 38519, a fungal metabolite, inhibits thrombin, serotonin in platelets, and bacteria growth.

Agent 38 from patent WO2015063714A1 (C) serves as an antibacterial for scientific study.

Nafcillin sodium: an antibiotic, β-lactamase inhibitor, treats staph infections.

Compd 3j (Antibacterial agent 149) is a laccase inhibitor that exhibits potent fungicidal activity, particularly useful in researching rice sheath blight [1].

AcrB-IN-1 (Compound H6) is a highly effective inhibitor of AcrB, utilized for the reversal of bacterial multidrug resistance [1].

Protein kinase G inhibitor-1 is a potent Protein kinase G inhibitor, IC50= 0.9 uM.

Antituberculosis agent-9 (Compound 5a), an orally administered compound, demonstrates potent antitubercular activity, exhibiting a minimum inhibitory

(R)-Ofloxacin is a R-isomer of Ofloxacin, an antibiotic used to treat a number of bacterial infections.

Methicillin sodium hydrate, a narrow-spectrum antibiotic, combats methicillin-resistant Staphylococcus strains and treats various infections.