Antibacterial
Antibacterial inhibitors are compounds that target bacterial cells, inhibiting their growth or killing them outright. These inhibitors are essential in the development of treatments for bacterial infections and are widely used in research to study bacterial physiology, resistance mechanisms, and the efficacy of new antibacterial agents. At CymitQuimica, we offer a range of antibacterial inhibitors to support your research in microbiology, infectious diseases, and drug development.
Found 3420 products of "Antibacterial"
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Antibacterial agent 172
CAS:Antibacterial Agent 172 (Compound 6a), a Clostridioides difficile (Cd) SpoVD inhibitor with an IC50 value of 89 nM, effectively inhibits the sporulation of Clostridioides difficile. It is useful for research on bacterial infections [1].Formula:C21H21N9O5S2Color and Shape:SolidMolecular weight:543.58Fostriecin (free base)
CAS:Fostriecin inhibits PP2A/PP4 (IC50s = 3.2/3 nM), weakly affects topoisomerase II/PP1 (IC50s = 40/131 μM), doesn't inhibit PP2B, and may modify epigenetics.Formula:C19H27O9PColor and Shape:SolidMolecular weight:430.39MK-3402
CAS:MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .Formula:C15H19N9O5S2Color and Shape:SolidMolecular weight:469.50Palmitanilide
CAS:Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.Formula:C22H37NOColor and Shape:SolidMolecular weight:331.535844-TFM
844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.Formula:C24H25F3N4O2Color and Shape:SolidMolecular weight:458.48MB076
CAS:MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Formula:C9H12BN7O5S2Color and Shape:SolidMolecular weight:373.18BAR-072
CAS:BAR-072 is a small molecule inhibitor targeting TraE with a KD value of 2.7 µM. It significantly suppresses the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 holds promise as a candidate molecule for research in disease areas related to infection and resistance control, by inhibiting the spread of bacterial resistance genes.Formula:C18H13N3O6Color and Shape:SolidMolecular weight:367.312Colistin adjuvant-2
Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].Formula:C14H7Cl2F3N2OColor and Shape:SolidMolecular weight:347.12OPC-167832
CAS:OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.Formula:C21H20ClF3N2O4Color and Shape:SolidMolecular weight:456.84ACHN-975
CAS:ACHN-975: potent LpxC inhibitor with subnanomolar activity; targets many gram-negative bacteria; MIC ≤1 μg/mL.Formula:C20H23N3O4Purity:98%Color and Shape:SolidMolecular weight:369.41Antimicrobial agent-38
CAS:Antimicrobial agent-38 (compound 10) effectively inhibits methicillin-resistant Staphylococcus aureus (S. aureus) strain ATCC 700699 and non-resistant strain ATCC 29213, with minimum inhibitory concentrations (MIC) of 32 mg/L and 64 mg/L, respectively.Formula:C14H11N3O4SColor and Shape:SolidMolecular weight:317.32Cilastatin ammonium salt
CAS:Cilastatin ammonium salt is an antibiotic that is particularly effective against Gram-positive cocci, with a half-life of 3-4 hours.Formula:C16H29N3O5SColor and Shape:SolidMolecular weight:375.48epi-D-Captopril
CAS:epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril and functions as an inhibitor of metallo-beta-lactamases (MBLs). The IC50 values of epi-D-Captopril for NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. This compound holds potential for research in MBLs-related antibiotic-resistant infections.Formula:C9H15NO3SColor and Shape:SolidMolecular weight:217.285Antibacterial agent 78
Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].Formula:C16H23N3S2Color and Shape:SolidMolecular weight:321.5Antibacterial synergist 1
Compound 20P is a potent antibacterial, inhibits biofilms with IC50 4.5 μM, and reduces pyocyanin at IC50 8.6 μM.Formula:C19H24N2O4Color and Shape:SolidMolecular weight:344.4(-)-15-Deoxyspergualin
CAS:(-)-15-Deoxyspergualin is a potent antitumor agent that demonstrates significant inhibition against mouse leukemia L-1210.Formula:C17H37N7O3Color and Shape:SolidMolecular weight:387.52Glutamate-5-kinase-IN-2
Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.Formula:C17H10ClFN2Color and Shape:SolidMolecular weight:296.73(R)-ZG197
(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.Formula:C28H35F3N4O3Color and Shape:SolidMolecular weight:532.6MurA-IN-6
CAS:MurA-IN-6 (Compound L16) is a selective MurA inhibitor with an IC50 of 26.63 μM. It exhibits antibacterial activity by inhibiting the function of MurA, a key protein essential for bacterial cell wall synthesis.Formula:C22H17N3O3SColor and Shape:SolidMolecular weight:403.454Gln-AMS TFA
Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.Formula:C17H23F3N8O10SColor and Shape:SolidMolecular weight:588.47Anticaries agent-1
CAS:Anticaries agent-1 (Compound 21b) is utilized as an anticaries agent. It effectively inhibits biofilm formation with an IC50 of 77 μM and restricts the growth of S. mutans.Formula:C15H12O4Color and Shape:SolidMolecular weight:256.253Pyrromycin
CAS:Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.Formula:C30H35NO11Color and Shape:SolidMolecular weight:585.60DC-159a
CAS:DC-159a, an 8-methoxy fluoroquinolone, possesses broad-spectrum antibacterial activity, with a particular efficacy against Gram-positive pathogens. The MIC90 values for DC-159a are 0.5 μg/mL against Streptococcus anginosus group, 4 μg/mL against Clostridium difficile, and 2 μg/mL against Bacteroides fragilis.Formula:C21H23F2N3O40·5H2OColor and Shape:SolidMolecular weight:428.4295BM635 hydrochloride
BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.Formula:C25H30ClFN2OColor and Shape:SolidMolecular weight:428.97Antifungal agent 27
Antifungal agent 27 shows moderate action against MRSA, weak against C. albicans, with MICs of 8 μg/mL and 32 μg/mL, respectively.Formula:C18H23N5OSColor and Shape:SolidMolecular weight:357.47Antibacterial agent 88
Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.Formula:C31H44N2O6SColor and Shape:SolidMolecular weight:572.76Antitubercular agent-16
Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.Formula:C21H27N3SColor and Shape:SolidMolecular weight:353.52FPI-1465
CAS:FPI-1465: Dual serine-β-lactamase & PBP inhibitor; IC50 PBP2=1.0 μg/mL; Kd CTX-M-15=0.011μM, OXA-48=5.3μM.Formula:C11H18N4O7SColor and Shape:SolidMolecular weight:350.35Elongation factor P-IN-2
Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.Formula:C16H35N3O2Color and Shape:SolidMolecular weight:301.47Gougerotin
CAS:Gougerotin is an inhibitor of protein synthesis.Formula:C16H25N7O8Color and Shape:SolidMolecular weight:443.41N6-Benzoyl-2'-deoxyadenosine monohydrate
CAS:N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analogue that helps diagnose bacterial infections by binding to double-stranded DNA and altering its structure, which can subsequently be detected using electrophoresis.Formula:C17H19N5O5Color and Shape:SolidMolecular weight:373.363(E)-Cefodizime
CAS:(E)-Cefodizime ((E)-THR-221) is an antibiotic that selectively binds to penicillin-binding proteins (PBPs), inhibiting bacterial cell wall synthesis, which results in its antibacterial activity. It holds potential for research into various bacterial infections, including the prevention of preoperative infections.Formula:C20H20N6O7S4Color and Shape:SolidMolecular weight:584.669Antibiofilm agent-4
CAS:Antibiofilm agent-4 is a LasR inhibitor, demonstrating optimal antibiofilm and anti-QS (quorum sensing) properties.Formula:C15H15NO3Molecular weight:257.28Mt KARI-IN-1
Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.Formula:C14H11N5O4S2Color and Shape:SolidMolecular weight:377.4BM635 mesylate
BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.Formula:C26H33FN2O4SColor and Shape:SolidMolecular weight:488.61Antitubercular agent-22
Antitubercular agent-22 combats Candida albicans (MIC: 2.34 μg/ml) and M. tuberculosis (MIC: 2 μg/ml).Formula:C24H28FN5O8Color and Shape:SolidMolecular weight:533.51FtsZ-IN-13
CAS:FtsZ-IN-13 (Compound C11) functions as an inhibitor of the temperature-sensitive mutant Z (FtsZ), exhibiting IC50 values of 47.97 μM for FtsZSa and 34 μM for FtsZPa. It demonstrates notable antibacterial activity against Staphylococcus aureus (with a minimum inhibitory concentration of 2 μg/mL), cystic fibrosis Staphylococcus aureus clinical isolates, and methicillin-resistant Staphylococcus aureus (MRSA). FtsZ-IN-13 is applicable in research on antibiotic resistance.Formula:C18H14N2O4S2Color and Shape:SolidMolecular weight:386.445Penethamate hydriodide
CAS:Penethamate hydriodide is a diethylaminoethyl ester prodrug of penicillin, utilized via intramuscular injection to treat mastitis in cattle.Formula:C22H32IN3O4SColor and Shape:SolidMolecular weight:561.4771,5-Dideoxy-1,5-imino-D-mannitol
CAS:1,5-Dideoxy-1,5-imino-D-mannitol is an antibiotic with antibacterial properties.Formula:C6H13NO4Color and Shape:SolidMolecular weight:163.172L 689065
CAS:L 689065 is a 5-lipoxygenase inhibitor.Formula:C35H33ClN2O3SPurity:98%Color and Shape:SolidMolecular weight:597.17MtTMPK-IN-9
MtTMPK-IN-9 moderately inhibits MtbTMPK (IC50: 48 μM), has submicromolar Mycobacterium activity, and is non-toxic, aiding tuberculosis research.Formula:C25H26N6O7Color and Shape:SolidMolecular weight:522.51Anti-MRSA agent 3
CAS:Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.Formula:C29H18BrN3O2Color and Shape:SolidMolecular weight:520.386Mycobacterium Tuberculosis-IN-6
CAS:Mycobacterium Tuberculosis-IN-6 (compound b1) is an inhibitor of the enoyl reductase InhA from Mycobacterium tuberculosis, with an IC50 value of 7.74 μM. It is useful in antibacterial research.Formula:C19H20FNOColor and Shape:SolidMolecular weight:297.367Antibacterial agent 81
CAS:Antibacterial agent 81 blocks DNA transcription, targets S. aureus (MIC 12.5μM) & M. smegmatis (MIC 7.8μM). Used in infection research.Formula:C33H28N2O8Color and Shape:SolidMolecular weight:580.58NBTI 5463
CAS:NBTI 5463 is a bacterial type II topoisomerase (topoisomerase II) inhibitor with antimicrobial properties. It effectively inhibits GyrA and TopoIV in Pseudomonas aeruginosa and Escherichia coli. By binding to topoisomerase II, NBTI 5463 prevents DNA cleavage and re-ligation, thereby impeding bacterial DNA replication and transcription. This compound shows potential for research into Gram-negative bacterial infections.Formula:C25H30N6O4Color and Shape:SolidMolecular weight:478.54RNAP-σ interaction inhibitor-2
CAS:RNAP-σ interaction inhibitor-2 (compound 7d) is an inhibitor targeting the interaction between RNA polymerase and the sigma factor. It demonstrates inhibitory activity against S. aureus with a minimum inhibitory concentration (MIC) of 2 µg/mL.Formula:C27H19Cl3N2O6S2Color and Shape:SolidMolecular weight:637.939Deprodone
CAS:Deprodone is an active compound that inhibits key processes such as bacterial cell wall synthesis by interacting with hydrolase and transferase proteins of methicillin-resistant Staphylococcus aureus (MRSA). It is applied in the research of MRSA infections, inflammatory skin diseases, intestinal disorders, and fatty acid metabolism disorders.Formula:C21H28O4Color and Shape:SolidMolecular weight:344.44PqsR-IN-2
PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.Formula:C18H20ClN3OSColor and Shape:SolidMolecular weight:361.89H2S scavenger 1 (triflate)
H2S scavenger 1 triflate (Compound 7b) serves as a selective H2S depleting agent, particularly against glutathione. This compound impedes the formation of bacterial biofilms and enhances the sensitivity of Staphylococcus aureus to gentamicin or photosensitizers by depleting H2S.Formula:C13H16F3N5O6SMolecular weight:427.36DNA Gyrase-IN-1
DNA Gyrase-IN-1: potent, selective promoter inhibitor. IC50: 2.6 μM, inhibits Mtb, MIC: 0.49 μM. Useful for tuberculosis research.Formula:C24H24FN7O6Color and Shape:SolidMolecular weight:525.49
