Antibacterial

<p>Ascr#18: nematode hormone boosts infection resistance in plants like Arabidopsis, tomato, potato, barley.</p>

<p>Compd 3j (Antibacterial agent 149) is a laccase inhibitor that exhibits potent fungicidal activity, particularly useful in researching rice sheath blight [1].</p>

<p>17-Hydroxyneomatrine, a compound derived from Sophora flavescens, exhibits multifaceted biological activities, including the inhibition of human cervical</p>

<p>Lysobactin (katanosin B) is an antibiotic effective against S. aureus, S. pneumoniae, and blocks PG biosynthesis.</p>

<p>AcrB-IN-1 (Compound H6) is a highly effective inhibitor of AcrB, utilized for the reversal of bacterial multidrug resistance [1].</p>

<p>(±)-Heraclenol, a coumarin derivative isolated from the fruits of Angelica lucida, exhibits antibacterial properties [1].</p>

<p>Angolamycin is a macrolide antibiotic (antibiotic) effective against Gram-positive bacteria.</p>

<p>Dodicin hydrochloride, an effective disinfectant, demonstrates broad antimicrobial activity [1].</p>

<p>SCH 38519, a fungal metabolite, inhibits thrombin, serotonin in platelets, and bacteria growth.</p>

<p>Bryostatin 1, a marine macrolide, permeates CNS and modulates PKC, with strong affinity for Munc13-1 (Ki: 8.07 nM and 0.45 nM).</p>

<p>Compound 12: a potent anti-MRSA, inhibits S. aureus/E. coli DNA gyrases/topo IV; IC50: 0.185-0.365/0.341-0.059 μM.</p>

<p>Renierone is an antimicrobial metabolite isolated from the marine sponge, Reniera sp.</p>

<p>Bicyclomycin is a broad spectrum antibiotic active against Gram-negative bacteria and the Gram-positive bacterium, Micrococcus luteusn.</p>

<p>Maximin 5, an antimicrobial peptide originating from the skin secretions of Bombina maxima, exhibits cytotoxicity against tumor cells and possesses spermicidal</p>

<p>Dermaseptin is a peptide expressed by the frog skin glands with a potent antimicrobial activity against bacteria, fungi and protozoa.</p>

<p>Methyl quinoline-2-carboxylate (Methyl 2-quinolinecarboxylate) inhibits the binding of Mycobacterium tuberculosis.</p>

<p>Sirpefenicol (ZTS-00007928), a phenicol antibacterial for treating animal bacterial infections.</p>

<p>Rabelomycin is an angucycline group antibiotic.</p>

<p>RvD4, derived from docosahexaenoic acid, reduces neutrophil infiltration and promotes phagocytosis/clearance by human cells.</p>

<p>Cethromycin (ABT-773) is an antibiotic of ketolide.</p>

<p>Amythiamicin A is an antibiotic effective against gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), and exhibits activity against Plasmodium falciparum.</p>

<p>c-di-AMP sodium: STING agonist, activates TBK3-IRF3 pathway, boosts type I IFN/TNF, regulates bacterial growth/virulence, and stimulates immune responses.</p>

<p>Aurein 5.2 is an antibiotic antimicrobial peptide [1].</p>

<p>Maximin H2, an antimicrobial peptide originating from the skin secretions of the Chinese red belly toad (Bombina maxima), exhibits inhibitory effects on a range</p>

<p>LAB 149202F is a bioactive chemical.</p>

<p>Maximin 3, an antimicrobial peptide originating from the skin secretions of Bombina maxima, exhibits cytotoxicity against tumor cells and possesses spermicidal</p>

<p>Ga(III)protoporphyrin-IX: soluble in MeOH, mimics malaria pigment, has strong antibacterial properties.</p>

<p>Linearmycin B, a polyene antibiotic from Streptomyces, causes B. subtilis lysis in Streptomyces Mg1 extract.</p>

<p>Alamethicin F50, a 20-amino acid peptaibol from Trichoderma, forms ion channels and has lytic and antibacterial properties.</p>

<p>(R)-Eucomol, a flavonoid derivative, exhibits slight antibacterial properties and demonstrates cytotoxic activity against KB and P-388 cells [1].</p>

<p>Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.</p>

<p>Faropenem daloxate (Faropenem medoxil) is useful for penem and antibiotics.</p>

<p>Doxycycline hydrochloride (Hyclate) is a synthetic tetracycline derivative with similar antimicrobial activity.</p>

<p>Narasin (sodium salt) (HainanMycin) induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells and</p>

<p>6-C-Methylquercetin-3,4'-dimethyl ether is a flavonol derivative extracted from Bauhinia thonningii Schum leaves, displaying antibacterial effects on Gram-</p>

<p>Monactin is a Marcrotetrolide antibiotic produced by cycloheximide producing species of Streptomyces. It is a homolog of nonactin from the same species.</p>

<p>Tuberculosis inhibitor 9 (compound 3d), a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative, exhibits potent activity against Mycobacterium tuberculosis and</p>

<p>D13-9001, an antibiotic, inhibits AcrB and MexB with KDs of 1.15μM in E. coli and 3.57μM in P. aeruginosa.</p>

<p>Dicloxacillin, a β-Lactam antibiotic, targets beta-lactamase bacteria like Staphylococcus aureus, defeating penicillin resistance.</p>

<p>Antibacterial 128, a siderophore-Ciprofloxacin blend with cleavable linker, targets P. aeruginosa and B. pseudomallei.</p>

<p>XT17 is an anthrone compound with broad-spectrum antibacterial activity, exerting its effects by disrupting the cell wall and inhibiting DNA synthesis. It demonstrates weak hemolytic activity, low cytotoxicity to mammalian cell lines, and a low rate of resistance development. Additionally, XT17 shows in vivo efficacy in a mouse corneal infection model induced by Staphylococcus aureus or Pseudomonas aeruginosa. Further docking studies confirm that XT17 forms a stable complex with bacterial gyrase. XT17 is suitable for research in the field of anti-infective agents.</p>

<p>Maximin 4, an antimicrobial peptide from Bombina maxima skin secretions, exhibits cytotoxic effects on tumor cells and spermicidal properties [1].</p>

<p>Antibacterial peptide. Stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of IκBα.</p>

<p>Agent 38 from patent WO2015063714A1 (C) serves as an antibacterial for scientific study.</p>

<p>Naphthalene is the simplest polycyclic aromatic hydrocarbon (PAH) and a major component of coal tar, serving as an insect repellent in camphor balls</p>

<p>Aurein 3.1 is an antibiotic antimicrobial peptide, whereas Aurein 2.6 demonstrates activity against Gram-positive bacteria, exhibiting minimum inhibitory</p>

<p>Ledaborbactam etzadroxil (VNRX-7145) is an orally active inhibitor of Ambler class A, C, and D β-lactamase enzymes.</p>

<p>GSK299423: Antibiotic possibly effective against bacteria with New Delhi metal-β-lactamase, targeting topoisomerases.</p>

<p>Flucloxacillin, an antibiotic, effectively combats both gram-positive and gram-negative bacteria [1] [2].</p>

<p>4-Methoxycoumarine has antitumour effects.</p>