Antibacterial

PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM.

Chevalone B, a meroterpenoid from E. chevalieri fungus, is cytotoxic with IC50s: KB cells 2.9 μg/ml, NCI-H187 9.8 μg/ml.

Urechistachykinin I (Uru-TK I) is an invertebrate kalinin-related peptide (TRPs) isolated from thylakoid nematodes.

XMP-629, an endotoxin inhibitor, is used potentially for the treatment of impetigo and acne rosacea.

<p>Hexa-D-arginine TFA (Furin Inhibitor II TFA) is an inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively).</p>

Aurein 5.2 is an antibiotic antimicrobial peptide [1].

Maximin H2, an antimicrobial peptide originating from the skin secretions of the Chinese red belly toad (Bombina maxima), exhibits inhibitory effects on a range

<p>2-Amino-6-bromopyridine has inhibitory effect on HIV-68 protease.</p>

<p>Cefotetan Sodium: a 2nd-gen cephamycin antibiotic effective against various aerobic/anaerobic, gram+/- bacteria, inhibits cell wall synthesis.</p>

Cefozopran is a fourth-generation cephalosporin.

<p>Cefsulodin, a β-lactam antibiotic, targets E. coli's penicillin-binding proteins, aiding with cell wall synthesis disruption.</p>

Maximin 3, an antimicrobial peptide originating from the skin secretions of Bombina maxima, exhibits cytotoxicity against tumor cells and possesses spermicidal

Midecamycin acetate is a broad-spectrum antibiotic active against Gram-positive and some Gram-negative strains.

ANT3310 inhibits several Serine β-Lactamases (IC50: 1-175 nM); useful for bacterial infection research.

Tylosin lactate: a vet macrolide antibiotic; broad vs. Gram-positive, limited on Gram-negative; from Streptomyces fradiae.

<p>Linearmycin B, a polyene antibiotic from Streptomyces, causes B. subtilis lysis in Streptomyces Mg1 extract.</p>

Alamethicin F50, a 20-amino acid peptaibol from Trichoderma, forms ion channels and has lytic and antibacterial properties.

C12-rrw-NH2 (Compound Lip7) is an antimicrobial agent effective against Gram-positive bacteria, particularly demonstrating significant activity against Methicillin-resistant Staphylococcus aureus (MRSA). It induces bacterial cell death by depolarizing the bacterial cell membrane, disrupting membrane integrity, causing nucleic acid and protein leakage, and promoting the generation of Reactive Oxygen Species (ROS). C12-rrw-NH2 is applicable in research focused on developing highly stable antimicrobial peptides.

<p>(R)-Eucomol, a flavonoid derivative, exhibits slight antibacterial properties and demonstrates cytotoxic activity against KB and P-388 cells [1].</p>

<p>Gemifloxacin is a fluoronaphthyridone with strong antibacterial effect.</p>