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HBV

HBV

HBV inhibitors are compounds designed to target and inhibit various stages of the Hepatitis B virus (HBV) lifecycle. These inhibitors can interfere with viral replication, assembly, or release, thereby reducing the viral load and helping to manage chronic HBV infections. Research into HBV inhibitors is crucial for developing effective antiviral therapies to prevent liver disease and cancer associated with HBV. At CymitQuimica, we offer a range of HBV inhibitors to support your research in virology, antiviral drug development, and infectious disease management.

Found 176 products of "HBV"

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  • HBV/HDV-IN-3

    CAS:
    <p>HBV/HDV-IN-3 (Compd 1) acts as a dual inhibitor for HBV and HDV, demonstrating an efficacy (EC 50) below 50 nM against HBV .</p>
    Formula:C28H27BrF3N5O3
    Color and Shape:Solid
    Molecular weight:618.44
  • SAG-524

    CAS:
    <p>SAG-524 is a powerful oral small molecule that inhibits HBV viral replication. In HepG2.2.15 cells, SAG-524 reduced HBV-DNA and HbsAg levels in the supernatant with IC₅₀ values of 0.92 nM and 1.4 nM, respectively [1].</p>
    Formula:C30H32ClN5O4S
    Color and Shape:Solid
    Molecular weight:594.12
  • HBV/HDV-IN-2

    CAS:
    <p>HBV/HDV-IN-2 (Compd 143) functions as an inhibitor for HBV, HDV, and PD-1/PD-L1, demonstrating an EC 50 of 35 nM in T cell activation.</p>
    Formula:C38H44ClN7O5
    Color and Shape:Solid
    Molecular weight:714.25
  • TLR8 agonist 4


    <p>TLR8 agonist 4 inhibits wild-type and lamivudine/entecavir-resistant HBV; IC50: 0.15 μM and 0.10 μM.</p>
    Formula:C28H27N5O5S
    Color and Shape:Solid
    Molecular weight:545.61
  • HBV-IN-12

    CAS:
    <p>HBV-IN-12: strong HBsAg &amp; HBV DNA inhibitor; EC50 0.001-0.05 μM &amp; 0.001-0.02 μM respectively. (WO2021204252A1)</p>
    Formula:C23H27NO8
    Color and Shape:Solid
    Molecular weight:445.46
  • HBV-IN-11

    CAS:
    <p>HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).</p>
    Formula:C21H24ClNO6
    Color and Shape:Solid
    Molecular weight:421.87
  • HBV-IN-18


    <p>HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).</p>
    Formula:C17H15F6N5O2
    Color and Shape:Solid
    Molecular weight:435.32
  • HBV-IN-48

    CAS:
    <p>HBV-IN-48, an HBV inhibitor, exhibits potent antiviral activity against HBV in HepDE19 cells, demonstrated by its EC 50 value of 0.005 μM. Additionally, it effectively reduces serum HBV DNA levels in mouse models of HBV infection.</p>
    Formula:C22H15F4N3O3
    Color and Shape:Solid
    Molecular weight:445.37
  • FNC-TP trisodium


    <p>FNC-TP trisodium, active intracellular FNC form, inhibits NRTI, fights HIV, HBV, and HCV.</p>
    Formula:C9H11FN6Na3O13P3
    Color and Shape:Solid
    Molecular weight:592.11
  • HBV-IN-31

    CAS:
    <p>HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.</p>
    Formula:C23H18ClNO6
    Color and Shape:Solid
    Molecular weight:439.85
  • HBV-IN-20


    <p>HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).</p>
    Color and Shape:Solid
  • ALG-000184

    CAS:
    <p>ALG-000184, a prodrug of the potent HBV capsid assembly modulator ALG-001075, shows potential for use in HBV infection research.</p>
    Formula:C23H20FN4Na2O8P
    Color and Shape:Solid
    Molecular weight:576.379
  • HBV-IN-19 TFA

    CAS:
    <p>HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.</p>
    Formula:C26H31F3N2O8
    Color and Shape:Solid
    Molecular weight:556.53
  • HBV-IN-34

    CAS:
    <p>HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA</p>
    Formula:C21H19F2N7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:407.42

    Ref: TM-T79469

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  • HBV-IN-38

    CAS:
    <p>HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].</p>
    Formula:C18H16F3N5O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:487.48

    Ref: TM-T79879

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  • Yhhu6669

    CAS:
    <p>Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in</p>
    Formula:C29H28ClFN6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:563.02

    Ref: TM-T78756

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