Other Inhibitors

<p>Brasilixanthone B is a useful organic compound for research related to life sciences and the catalog number is T124115.</p>

<p>DB008 is a selective PARP16 inhibitor with IC50 of 0.27 μM, has acrylamide, and is membrane-permeable.</p>

<p>OA2 lipid is an ionizable lipid that can form single-component lipid nanoparticles (LNPs) for the delivery of RNA.</p>

<p>Pepsinostreptin is a pepsin inhibitor that forms a 1:1 complex with pepsin and suppresses its activity.</p>

<p>Difelikefalin: KOR agonist, active in human cells (EC50=0.16 nM), and mouse cells (EC50=0.048 nM), selective over MOR, reduces pain and itch in mice.</p>

<p>Acronyculatin Q is a useful organic compound for research related to life sciences and the catalog number is T125276.</p>

<p>WDR5-IN-4 TFA blocks WDR5's WIN site with 0.1 nM affinity, reducing gene expression and showing anti-cancer properties.</p>

<p>L735821 is a bioactive chemical.</p>

<p>Indole-3-acrylic acid methyl ester is a useful organic compound for research related to life sciences and the catalog number is T125447.</p>

<p>1,3-Dieicosatrienoin is a diacylglycerol that has 11(Z),14(Z),17(Z)-eicosatrienoic acid at the sn-1 and sn-3 positions.</p>

<p>S-palm P0(180–199) (TFA) is a peptide that enhances MHC II-restricted responses. It is utilized to develop models of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and chronic experimental autoimmune neuritis (c-EAN). S-palm P0(180–199) (TFA) is also studied in the context of autoimmune-mediated neuritis.</p>

<p>(+)-Wikstromol is a useful organic compound for research related to life sciences and the catalog number is T130443.</p>

<p>Compound 0449-0121 is a useful organic compound for research related to life sciences and the catalog number is T131654.</p>

<p>Eniclobrate (Sgd 33374) is a diphenylmethane derivative known for its lipid-lowering effects.</p>

<p>Suc-AEPF-AMC (Suc-Ala-Glu-Pro-Phe-AMC) is a peptide substrate for the peptidyl prolyl isomerases Pin1 and Par14, and is a peptide compound that can be used to assay protease activity.</p>

<p>Ruixianglangdusu B is a natural product that can be used as a reference standard.</p>

<p>5α,8α-Epidioxyergost-6-en-3β-ol is a useful organic compound for research related to life sciences and the catalog number is T124161.</p>

<p>Gramicidin S 2HCl, is an antibiotic. At concentrations of 40-80 μg/mL, GS can reduce planktonic cell numbers within 20-40 minutes. For established biofilms, it effectively kills cells at concentrations of 100-200 μg/mL without regrowth. This anti-biofilm effect results from peptide transmembrane transport and complexation with intracellular nucleotides (including the alarmone ppGpp). GS demonstrates wide-ranging activity against biofilm-forming, drug-resistant infections caused by E. faecalis, proving its efficacy in endodontic treatment. The successful treatment of persistent infections in two volunteer cases further confirms GS's potent therapeutic performance. These studies indicate that GS can be applied in certifying compounds used in endodontics.</p>

<p>VICENISTATIN is a novel compound capable of inducing the vesiculation of early endosomes. It promotes the formation of vesicle-like structures by activating the Rab5-PAS pathway and enhancing membrane fluidity. Additionally, VICENISTATIN functions as an antitumor antibiotic, demonstrating antitumor activity against human colon cancer Co-3 in xenograft models.</p>

<p>Compound N064-0048 is a useful organic compound for research related to life sciences and the catalog number is T131201.</p>