Other Inhibitors

Tetraethylammonium hexachlorocerate(IV) is a useful organic compound for research related to life sciences and the catalog number is T64591.

Azido-PEG6-azide, a PEG-based PROTAC linker, is used in the synthesis of PROTACs [1].

Piperazine (2HCl) is gamma-aminobutyric acid (GABA) agonists and its major effects appear to be on the central nervous system. Piperazine was the anthelmintic with the greatest number of reports of toxicoses and suspected toxicoses in cats. Piperazine neurotoxicity in cats and dogs usually was manifested by muscle tremors, ataxia, and/or behavioral disturbances within 24 hours after estimated daily dose(s) between 20 and 110 mg/kg[1]. For di-substituted derivatives, ciprofloxacin was selected and hybrids were synthesized via substitution at piperazinyl-N4. The reaction of piperazinyl-NH of ciprofloxacin with selected drugs resulted in pronounced growth inhibition of standard as well as resistant bacterial strains[2]. The parent piperazine 6 was found to exhibit a reasonable activity toward the HeLa and MDA MB 231 tumor cell lines (IC50= 9.2 and 8.4 μΜ, respectively)[3]. Piperazine adipate (10 mM) causes mortality of A. galli and H. gallinae after a maximum of 30 min exposure, inhibits malate oxidation by 78%, and inhibits aldolase activity in both parasites. Piperazine adipate (10 mM) also inhibits cholinesterase activity by 96% in Ascaridia galli (A. galli) and 93% in Heterakis gallinae (H. gallinae). Piperazine adipate inhibits oxaloacetate reduction by 26% and 55% in A. galli and H. gallinae, resepctively[4].

2-Amino-3-(2-fluorophenyl)propanoic acid is a valuable organic compound for life sciences research [catalog number: T67303, CAS number: 2629-55-2].

2-Ethylphenol is a useful organic compound for research related to life sciences. The catalog number is T66251 and the CAS number is 90-00-6.

Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66601 and the CAS number is 1243308-37-3.

4-Chloro-N,N-dimethylpicolinamide is a useful organic compound for research related to life sciences. The catalog number is T67664 and the CAS number is 114780-06-2.

Octyl glucose neopentyl glycol (OGNG) is a detergent derived from neopentyl glycol, designed to stabilize membrane proteins [1].

(R)-3-([1,1'-Biphenyl]-4-yl)-2-aminopropanoic acid is a useful organic compound for research related to life sciences and the catalog number is T67381.

(S)-4-[2-(Diphenylphosphino)-1-naphthalenyl]-N-[(R)-1-phenylethyl]-1-phthalazinamine is a useful organic compound for research related to life sciences and the catalog number is T67270.

m-PEG8-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs.

5-(2-Bromoacetyl)-2-hydroxybenzaldehyde is a useful organic compound for research related to life sciences. The catalog number is T66272 and the CAS number is 115787-50-3.

10× TBS (PH7.4) is a reagent and has a wide range of applications in life science related research.

2-(Trifluoromethyl)cinnamic acid is a useful organic compound for research related to life sciences. The catalog number is T64859 and the CAS number is 2062-25-1.

D-Luciferin 6′-methyl ether (also known as 6′-Methoxyluciferin or compound 19a) is a highly effective inhibitor of luciferase obtained from the North American firefly Photinus pyralis (PpyLuc), exhibiting an IC50 value of 0.1 μM. This analog of D-luciferin interacts non-specifically with the ATP and luciferin binding sites within the active site of PpyLuc.

(R)-2-Benzylsuccinic acid is a useful organic compound for research related to life sciences and the catalog number is T67007.

(7Z)-Monomyristolein is a useful organic compound for research related to life sciences. The catalog number is TF0001 and the CAS number is 749266-35-1.

Boc-D-Ala-OSu is a useful organic compound for research related to life sciences. The catalog number is T65028 and the CAS number is 34404-33-6.

SulfoxFluor has a wide range of applications in life science related research.