Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
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PROTAC BCR-ABL1 ligand 1
CAS:<p>GMB-475 is a PROTAC ligand targeting BCR-ABL1 for degradation via E3 ligase recruitment.</p>Formula:C17H12F3N3O2Color and Shape:SoildMolecular weight:347.29hAChE-IN-1
<p>hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.</p>Formula:C22H24N4OColor and Shape:SolidMolecular weight:360.45SNIPER(ABL)-013
<p>SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of</p>Formula:C42H52F3N7O8Purity:98%Color and Shape:SolidMolecular weight:839.9SMART1
<p>SMART1 is a CRBN-dependent PROTAC with high specificity that effectively degrades Smurf1. It inhibits tumor growth in xenograft models of colorectal cancer (CRC) with KRAS mutations and blocks the PDK1-Akt signaling pathway in KRAS-mutated colorectal cancer.</p>Formula:C40H35N9O7Color and Shape:SolidMolecular weight:753.76Tabituximab barzuxetan
CAS:<p>Tabituximab barzuxetan: Humanized antibody FZD-10-targeted, Yttrium-90 labeled, for synovial sarcoma research.</p>Color and Shape:SolidAKT1-IN-9
<p>AKT1-IN-9 (4) is a selective inhibitor of the AKT1(E17K) mutation, exhibiting EC50 values of 9 nM in LAPC4-CR cells and 995 nM in SkBr3 cells.</p>Formula:C33H25FN6O4Color and Shape:SolidMolecular weight:588.588DSPE-PEG2000-iRGD
<p>DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.</p>Color and Shape:Odour SolidZolbetuximab MMAE
<p>Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.</p>Purity:95% - 95%Color and Shape:LiquidMolecular weight:150 kDaK34c hydrochloride
CAS:<p>K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.</p>Formula:C26H30ClN3O4Purity:99.76% - 99.89%Color and Shape:SoildMolecular weight:483.99Sudocetaxel
CAS:<p>Sudocetaxel is a compound that serves as a microtubule depolymerization inhibitor, specifically designed for the pH-sensitive delivery of docetaxel.</p>Formula:C48H59NO16Color and Shape:SolidMolecular weight:905.9819-O-Acetylchaetoglobosin A
CAS:<p>19-O-Acetylchaetoglobosin A, from C. globosum, inhibits actin polymerization and is cytotoxic to HeLa cells at 3.2-32 μg/ml.</p>Formula:C34H38N2O6Color and Shape:SolidMolecular weight:570.686LXY3
CAS:<p>LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.</p>Formula:C32H43N11O15S2Color and Shape:SolidMolecular weight:885.88Epothilone F
CAS:<p>Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.</p>Formula:C27H41NO7SColor and Shape:SolidMolecular weight:523.68ZIP
CAS:<p>Novel inhibitor for PKMζ, halts synaptic potentiation and reverses LTP with IC50 of 1-2.5 μM, erasing spatial memory.</p>Formula:C90H154N30O17Purity:98%Color and Shape:SolidMolecular weight:1928.4Foxy-5
CAS:<p>Foxy-5 is a wnt5a peptide mimetic</p>Formula:C26H42N6O12S2Purity:98%Color and Shape:SolidMolecular weight:694.77DSPE-PEG2000-cRGD
<p>DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.</p>Color and Shape:Odour SolidSNIPER(ABL)-058
CAS:<p>SNIPER(ABL)-058, a compound that links Imatinib (ABL inhibitor) with a derivative of LCL161 (IAP ligand) through a linker, effectively decreases BCR-ABL protein</p>Formula:C62H75N11O9SPurity:98%Color and Shape:SolidMolecular weight:1150.39Larazotide
CAS:<p>Larazotide: octapeptide from V. cholerae, treats Coeliac disease by inhibiting paracellular permeability.</p>Formula:C32H55N9O10Purity:98%Color and Shape:SolidMolecular weight:725.83GRGDSP
CAS:<p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>Formula:C22H37N9O10Purity:98%Color and Shape:SolidMolecular weight:587.58Osemitamab (FUT8-KO)
<p>Osemitamab (FUT8-KO) is a monoclonal antibody targeting claudin-18.2, expressed in CHO cells with a knockout of the fucosyltransferase 8 gene (FUT8). The absence of fucose heightens the antibody's ADCC effect. When combined with Capecitabine and Oxaliplatin, it can be used for G/GEJ cancer research.</p>Color and Shape:Odour Liquid
