Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Phosphatidylserines (bovine)
CAS:<p>Phosphatidylserine: a natural phospholipid, 2-10% in mammals, CNS-rich, synthesized in ER, involved in cell signaling, apoptosis marker.</p>Formula:C42H78NO10P(foroleoyl)Color and Shape:SolidMolecular weight:788.1Larazotide
CAS:<p>Larazotide: octapeptide from V. cholerae, treats Coeliac disease by inhibiting paracellular permeability.</p>Formula:C32H55N9O10Purity:98%Color and Shape:SolidMolecular weight:725.83RA-PR058
<p>RA-PR058 is an orally active Ramalin derivative capable of penetrating the blood-brain barrier, with multi-target regulatory functions. By reducing BACE1 expression, decreasing excessive tau protein phosphorylation, and mitigating anxiety-like behaviors, along with displaying favorable pharmacokinetic properties, RA-PR058 shows promise as a multi-target modulator for Alzheimer's disease.</p>Formula:C11H15ClF3N3OColor and Shape:SolidMolecular weight:297.7Gamitrinib TPP hexafluorophosphate
CAS:<p>Gamitrinib TPP hexafluorophosphate is a mitochondrial-targeted HSP90 inhibitor with anticancer activity that can be used to study cancer and viral infection.</p>Formula:C52H65F6N3O8P2Purity:98.52% - 98.52%Color and Shape:SolidMolecular weight:1036.03hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Color and Shape:Odour SolidSangivamycin
CAS:<p>Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.</p>Formula:C12H15N5O5Purity:99.85%Color and Shape:SolidMolecular weight:309.286BrCaQ-C10-TPP
<p>6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.</p>Formula:C45H47Br2N2O3PColor and Shape:SolidMolecular weight:854.656-Epi-ophiobolin G
<p>6-Epi-ophiobolin G (MHO7) is a marine-derived fungal metabolite that serves as an orally active Akt inhibitor capable of crossing the blood-brain barrier. It effectively inhibits the proliferation of glioblastoma (GBM) cells and promotes apoptosis. 6-Epi-ophiobolin G (MHO7) is suitable for research in glioblastoma studies.</p>Formula:C24H32O2Color and Shape:SolidMolecular weight:352.24023SNIPER(ABL)-015
<p>SNIPER(ABL)-015, a compound that conjugates GNF5 (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of 5</p>Formula:C58H70F3N9O9Purity:98%Color and Shape:SolidMolecular weight:1094.23Alvespimycin TFA
<p>Alvespimycin (17-DMAG) TFA is a potent inhibitor of Hsp90, binding with an EC50 of 62 ± 29 nM.</p>Formula:C34H49F3N4O10Color and Shape:SolidMolecular weight:730.34008Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg
CAS:<p>Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg is a protein kinase C substrate.</p>Formula:C56H110N22O14Purity:98%Color and Shape:SolidMolecular weight:1315.61MS98
CAS:<p>MS98, a specific PROTAC AKT degrader, depletes T-AKT with DC50 of 78 nM; binds AKT1, AKT2, AKT3 with Kds of 4, 140, 8.1 nM.</p>Formula:C58H81ClN10O7SColor and Shape:SolidMolecular weight:1097.86Gantofiban
CAS:<p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>Formula:C21H29N5O6Purity:99.57%Color and Shape:SolidMolecular weight:447.48HSDVHK-NH2
CAS:<p>Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.</p>Formula:C30H48N12O9Purity:98%Color and Shape:SolidMolecular weight:720.78Abl Cytosolic Substrate
CAS:<p>Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ).</p>Formula:C64H101N15O16Purity:98%Color and Shape:SolidMolecular weight:1336.58Tubulin inhibitor 38
<p>Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell</p>Formula:C17H13ClN6OSColor and Shape:SolidMolecular weight:384.84Solidagonic acid
CAS:<p>Solidagonic acid inhibits HSET, prevents fission yeast cell death, and hinders L. sativa and L. multiflorum seedling growth.</p>Formula:C22H34O4Color and Shape:SolidMolecular weight:362.5SMS 121
CAS:<p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>Formula:C20H21NO5Purity:98.29%Color and Shape:SoildMolecular weight:355.38Combretastatin A-1 phosphate tetrasodium
CAS:<p>OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.</p>Formula:C18H18Na4O12P2Color and Shape:SolidMolecular weight:580.24LXY3
CAS:<p>LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.</p>Formula:C32H43N11O15S2Color and Shape:SolidMolecular weight:885.88
