Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
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SNIPER(ABL)-024
CAS:<p>SNIPER(ABL)-024, a compound that conjugates GNF5 (ABL inhibitor) to an LCL161 derivative (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels,</p>Formula:C52H61F3N8O9SPurity:98%Color and Shape:SolidMolecular weight:1031.15MS143
CAS:<p>MS143: potent AKT degrader, DC50=46 nM, GI50=0.8 µM in PC3 cells, degrades AKT via ubiquitin-proteasome, suppresses cancer growth.</p>Formula:C59H81ClN12O6SColor and Shape:SolidMolecular weight:1121.87Tyrosine Kinase Inhibitor Library
<p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>Color and Shape:Odour SolidAlvespimycin TFA
<p>Alvespimycin (17-DMAG) TFA is a potent inhibitor of Hsp90, binding with an EC50 of 62 ± 29 nM.</p>Formula:C34H49F3N4O10Color and Shape:SolidMolecular weight:730.34008ML-B01
<p>ML-B01 is an orally active inhibitor targeting Akt and PKA, with IC50 values of 2 nM and 136 nM, respectively. It demonstrates good blood-brain barrier (BBB) permeability in mice.</p>Formula:C24H31Cl2N5OColor and Shape:SolidMolecular weight:476.44KIF2C-IN-1
<p>KIF2C-IN-1 (Compound 7S9) is a selective and potent small molecule inhibitor of KIF2C. It stabilizes the interaction between KIF2C and microtubule proteins, preventing the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel in Paclitaxel-resistant triple-negative breast cancer (TNBC) cells and, when combined with Paclitaxel, significantly reduces tumor growth in mouse models.</p>Formula:C36H39ClN4O9SColor and Shape:SolidMolecular weight:738.21263TNIK-IN-7
CAS:<p>TNIK-IN-7 is a Traf2 and Nck interacting kinase (TNIK) inhibitor with antitumor activity for the study of signaling and proliferation in colorectal cancer cells</p>Formula:C23H22N4O2Purity:99.87%Color and Shape:SoildMolecular weight:386.45AT-1002
CAS:<p>AT-1002 is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.</p>Formula:C32H53N9O7SPurity:98%Color and Shape:SolidMolecular weight:707.88TAT-Gap19
CAS:<p>Cx43 blocker, IC50 ~7μM; doesn't affect gap junctions/Panx1. TAT motif enhances effect; works in vivo, brain-penetrant.</p>Formula:C119H212N46O26Purity:98%Color and Shape:SolidMolecular weight:2703.28SMS 121
CAS:<p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>Formula:C20H21NO5Purity:98.29%Color and Shape:SoildMolecular weight:355.38INY-03-041 trihydrochloride
<p>INY-03-041 trihydrochloride: potent, selective PROTAC AKT degrader; combines Ipatasertib and Lenalidomide; IC50s: AKT1 (2.0 nM), AKT2 (6.8 nM), AKT3 (3.5 nM).</p>Formula:C44H59Cl4N7O5Color and Shape:SolidMolecular weight:907.8AS-605240 potassium
<p>AS-605240 (potassium) is an orally active PI3Kγ inhibitor with an IC50 of 8 nM and a Ki of 7.8 nM. It inhibits MCP-1 and CSF1-induced PKB phosphorylation with IC50 values of 0.181 µM and 0.550 µM, respectively. In mouse models of peritonitis induced by RANTES (CCL5) and thioglycolate, AS-605240 (potassium) reduces neutrophil recruitment, showing EC50 values of 9.1 mg/kg and 10 mg/kg. Additionally, AS-605240 (potassium) ameliorates arthritis induced by αCII-IA in mice.</p>Formula:C12H6KN3O2SColor and Shape:SolidMolecular weight:294.98178PM050489
CAS:<p>PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.</p>Formula:C31H44ClN3O7Color and Shape:SolidMolecular weight:606.15Cyclo(RGDfC) TFA
<p>Zelminemab (AMG-301) is a humanized monoclonal antibody targeting ADCYAP1R1 for use in neurological disorders.</p>Formula:C26H35F3N8O9SPurity:98.59%Color and Shape:SolidMolecular weight:692.67Kinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Color and Shape:Odour Solidc(phg-isoDGR-(NMe)k) TFA
<p>C(phg-isoDGR-(NMe)k) TFA is a selective and potent ligand for α5β1-integrin, exhibiting an IC50 of 2.9 nM [1].</p>Formula:C29H42F3N9O9Color and Shape:SolidMolecular weight:717.69Tubulin polymerization-IN-78
<p>Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.</p>Color and Shape:Odour Solidpara-amino-Blebbistatin
CAS:<p>para-amino-Blebbistatin is a water-soluble, stable, non-phototoxic inhibitor of non-muscle myosin II, with enhanced properties over blebbistatin.</p>Formula:C18H17N3O2Color and Shape:SolidMolecular weight:307.353Solidagonic acid
CAS:<p>Solidagonic acid inhibits HSET, prevents fission yeast cell death, and hinders L. sativa and L. multiflorum seedling growth.</p>Formula:C22H34O4Color and Shape:SolidMolecular weight:362.5K34c hydrochloride
CAS:<p>K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.</p>Formula:C26H30ClN3O4Purity:99.76% - 99.89%Color and Shape:SoildMolecular weight:483.99
