Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
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PDI-IN-4
<p>PDI-IN-4 (Compound 14d) is a protein disulfide isomerase inhibitor with an IC50 value of 0.48 μM. It prevents platelet aggregation and thrombosis by reducing the activation of GPIIb/IIIa, without causing significant cytotoxicity. PDI-IN-4 is applicable in thrombosis research.</p>Formula:C17H12F3NO2Color and Shape:SolidMolecular weight:319.278Microtubule-associated protein tau (26-44)
<p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>Formula:C83H127N25O34SPurity:98%Color and Shape:SolidMolecular weight:2051.11Odulimomab
CAS:<p>Odulimomab: anti-LFA-1 antibody, inhibits T cell growth, protects against ischemic injury, used in transplant rejection research.</p>Color and Shape:LiquidLY 379196
<p>LY 379196, a potent PKC-β inhibitor (IC 50: 50 nM for PKC βI and 30 nM for PKC βII), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.</p>Formula:C30H34N4O5SColor and Shape:SolidMolecular weight:562.68Hypoglycemic agent 3
<p>Compound H26, a derivative of corosolic acid, functions as Hypoglycemic agent 3. It exhibits lipid-lowering and significant blood glucose-reducing properties, making it a potential hypoglycemic drug. Hypoglycemic agent 3 targets MCCC1 to mitigate insulin resistance, and may be useful in researching type 2 diabetes.</p>Formula:C32H51NO5Color and Shape:SolidMolecular weight:529.751Anticancer agent 139
<p>Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a π-cationic interaction with Lys352 of Tubulin and demonstrating high</p>Formula:C16H12F3N3OColor and Shape:SolidMolecular weight:319.28Bimosiamose
CAS:<p>Bimosiamose has anti-inflammatory effects[1].</p>Formula:C46H54O16Purity:98%Color and Shape:SolidMolecular weight:862.91Tubulin inhibitor 36
<p>Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,</p>Formula:C16H13ClN6SColor and Shape:SolidMolecular weight:356.83YS-49 monohydrate
<p>YS-49, a PI3K/Akt activator, curbs RhoA/PTEN; inhibits VSMC growth by inducing HO-1; an isoquinoline alkaloid that stimulates cardiac β-adrenoceptors.</p>Formula:C20H22BrNO3Color and Shape:SolidMolecular weight:404.3MAL3-101
CAS:<p>MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).</p>Formula:C54H66N4O10Color and Shape:SolidMolecular weight:931.12JG-258
CAS:<p>JG-258 is an inactive negative control for Hsp70 inhibitors [1] .</p>Formula:C20H22ClN3OS3Color and Shape:SolidMolecular weight:452.06Arimoclomol citrate
CAS:<p>Arimoclomol citrate boosts Hsp expression, aiding protein aggregation and neuron protection.</p>Formula:C20H28ClN3O10Color and Shape:SolidMolecular weight:505.91Rotigaptide
CAS:<p>Rotigaptide, modulates Cx43 for gap junctions, counteracts uncoupling, and maintains communication under stress.</p>Formula:C28H39N7O9Purity:98%Color and Shape:SolidMolecular weight:617.65DSPE-PEG1000-iRGD
<p>DSPE-PEG1000-iRGD is a PEG compound made from DSPE and the αv-integrin-targeting peptide (iRGD). The iRGD peptide initially binds to αv-integrins and undergoes proteolytic cleavage within tumors to produce CRGDK/R, which interacts with neuropilin-1, thereby facilitating tumor targeting and penetration. DSPE-PEG1000-iRGD is useful for drug delivery applications.</p>Color and Shape:Odour SolidPROTAC BCR-ABL Degrader-1
<p>PROTAC BCR-ABL Degrader-1 (compound PROTAC 1), featuring a 2-oxoethyl linker, promotes Bcr-Abl degradation through the ubiquitin-proteasome pathway and</p>Formula:C43H40N10O6Purity:98%Color and Shape:SolidMolecular weight:792.84Crosstide
CAS:<p>Crosstide is a peptide analog of glycogen synthase kinase-3 (GSK-3) that functions as a natural substrate for Akt/PKB.</p>Formula:C48H77N17O17Purity:98%Color and Shape:SolidMolecular weight:1164.23Pironetin
CAS:<p>Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.</p>Formula:C19H32O4Purity:98%Color and Shape:SolidMolecular weight:324.45ALB-109564 dihydrochloride
CAS:<p>ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.</p>Formula:C47H62Cl2N4O9SPurity:98%Color and Shape:SolidMolecular weight:929.99para-amino-Blebbistatin
CAS:<p>para-amino-Blebbistatin is a water-soluble, stable, non-phototoxic inhibitor of non-muscle myosin II, with enhanced properties over blebbistatin.</p>Formula:C18H17N3O2Color and Shape:SolidMolecular weight:307.353Tubulin polymerization-IN-53
<p>Tubulin polymerization-IN-53 (compound 4b) serves as an inhibitor of β-tubulin polymerization and is capable of arresting the cell cycle at the G2/M stage.</p>Color and Shape:Odour Solid
