Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
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PDS-0330
CAS:<p>PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.</p>Formula:C25H17N3O2SPurity:99.93%Color and Shape:SoildMolecular weight:423.49Phomopsin A
CAS:<p>Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.</p>Formula:C36H45ClN6O12Purity:98%Color and Shape:SolidMolecular weight:789.23JG-258
CAS:<p>JG-258 is an inactive negative control for Hsp70 inhibitors [1] .</p>Formula:C20H22ClN3OS3Color and Shape:SolidMolecular weight:452.06AT-1002
CAS:<p>AT-1002 is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.</p>Formula:C32H53N9O7SPurity:98%Color and Shape:SolidMolecular weight:707.88TBL-100
<p>TBL-100 is a human monoclonal antibody (mAb) that targets Tau. It is applicable for research in Alzheimer's disease (AD) and progressive supranuclear palsy.</p>Color and Shape:Odour LiquidNDNA4
<p>NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent charge and low membrane permeability.</p>Formula:C31H35F3N2O5SPurity:98%Color and Shape:SolidMolecular weight:604.68A20FMDV2
CAS:<p>A20FMDV2 is a highly selective αvβ6 integrin inhibitor with an IC 50 of 3 nM, demonstrating 1,000-fold greater selectivity for αvβ6 compared to other RGD-directed integrins like αvβ3, αvβ5, and α5β1. This compound can be derived from the foot-and-mouth disease virus and is suitable for radiolabeling, enabling PET imaging of αvβ6 integrin-positive tumors.</p>Formula:C93H163N31O28Color and Shape:SolidMolecular weight:2163.48LDV-FITC TFA
<p>LDV-FITC TFA is a fluorescent peptide, specifically an FITC-conjugated LDV peptide. This compound binds to the α4β1 integrin with high affinity, displaying a Kd of 0.3 nM in the presence of Mn2+ and 12 nM in its absence, when binding to U937 cells. LDV-FITC TFA is useful for assessing α4β1 integrin affinity.</p>Formula:C69H81N11O17S·xC2HF3O2SAMβA TFA
<p>SAMβA TFA, a selective antagonist of Mfn1-βIIPKC association conjugated to the cell permeable peptide TAT47-57, is a rationally designed inhibitor that improves</p>Formula:C50H73N17O16·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:1168.22 (free acid)cRGDfK-thioacetyl ester
CAS:<p>cRGDfK-thioacetyl ester, a bioactive polypeptide, exhibits selective affinity for integrins and can modify near-infrared (NIR) fluorescent probes for targeted</p>Formula:C31H45N9O9SPurity:98%Color and Shape:SolidMolecular weight:719.81hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Color and Shape:Odour SolidKTC1101
CAS:<p>KTC1101 is a pan-PI3K inhibitor with antiproliferative and anticancer activities, reducing phosphorylation of downstream AKT and mTOR.</p>Formula:C21H26F2N8O3Purity:98.75%Color and Shape:SoildMolecular weight:476.48Sangivamycin
CAS:<p>Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.</p>Formula:C12H15N5O5Purity:99.85%Color and Shape:SolidMolecular weight:309.28Chaetominine
CAS:<p>Chaetominine is a type of cytotoxic alkaloid obtained from endophytic Chaetomium sp. IFB-E015.</p>Formula:C22H18N4O4Color and Shape:SolidMolecular weight:402.406BrCaQ-C10-TPP
<p>6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.</p>Formula:C45H47Br2N2O3PColor and Shape:SolidMolecular weight:854.65AT7867 dihydrochloride
CAS:<p>AT7867 dihydrochloride inhibits Akt1/2/3 and p70S6K/PKA, with IC50s: 32/17/47 nM & 85/20 nM, respectively, and hampers tumor growth.</p>Formula:C20H22Cl3N3Color and Shape:SolidMolecular weight:410.77Debio 0932
CAS:<p>Debio 0932 (CUDC-305) is a Hsp9 inhibitor, apoptosis, and has the advantage of being orally available and cross the BBB for cancers NSCLC and neuroblastoma.</p>Formula:C22H30N6O2SPurity:98.98%Color and Shape:SolidMolecular weight:442.58(±)-1,2-Diolein
CAS:<p>(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.</p>Formula:C39H72O5Color and Shape:SolidMolecular weight:620.99Kinesore
CAS:<p>Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.</p>Formula:C20H16Br2N4O4Purity:97.24%Color and Shape:SolidMolecular weight:536.17Cilengitide TFA
CAS:<p>Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.</p>Formula:C29H41F3N8O9Color and Shape:SolidMolecular weight:702.68
