Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
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MC-Val-Cit-PAB-Ispinesib
CAS:<p>MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].</p>Formula:C59H71ClN10O10Color and Shape:SolidMolecular weight:1115.71β-Catenin modulator-2
CAS:<p>β-Catenin Modulator-2 (Compound IIa-130), which is an oxazole-thiazole derivative, serves as a potent and selective modulator of β-Catenin [1].</p>Formula:C20H18Cl2N2O3SColor and Shape:SolidMolecular weight:437.34CNS-11
CAS:<p>CNS-11, a compound that disaggregates tau fibrils, is utilized in Alzheimer's disease (AD) research [1].</p>Formula:C25H21N3O2Color and Shape:SolidMolecular weight:395.45PTK7/β-catenin-IN-1
CAS:<p>PTK7/β-catenin-IN-1 (compound 01065) is a potent inhibitor targeting PTK7/β-catenin and p53/MDM2, with IC50 values of 8.9 μM and 56.5 μM, respectively. This compound shows promise for cancer research applications [1].</p>Formula:C22H16N2O2Color and Shape:SolidMolecular weight:340.382BI-1950
CAS:<p>BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.</p>Formula:C32H26Cl2FN7O3Purity:98%Color and Shape:SolidMolecular weight:646.5BX-2819
CAS:<p>BX-2819 is an Hsp90 inhibitor that exhibits potent antiproliferative activity with an IC50 of 41 nM .</p>Formula:C21H24N4O4SPurity:98%Color and Shape:SolidMolecular weight:428.51UU-T01
CAS:<p>UU-T01 inhibits β-catenin/Tcf4 with Ki of 3.14 µM, binds β-catenin directly with KD of 0.531 µM.</p>Formula:C10H10N6OColor and Shape:SolidMolecular weight:230.23Teclistamab
CAS:<p>Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.</p>Purity:95%Color and Shape:Liquidβ-Catenin modulator-5
CAS:<p>β-Catenin Modulator-5 (Compound IIa-84), an oxazole and thiazole-based compound, serves as a potent and selective modulator of β-Catenin [1].</p>Formula:C21H22N2O2SColor and Shape:SolidMolecular weight:366.48Flavokawain 1i
CAS:<p>Flavokawain 1i, a derivative of chalcones flavokawain A, flavokawain B, and flavokawain C, exhibits anticancer and antiviral properties.</p>Formula:C21H18O4Color and Shape:SolidMolecular weight:334.37AKT-I-1
CAS:<p>AKT-I-1 is a selective and reversible inhibitor of Akt1.</p>Formula:C22H30N6Purity:99.89%Color and Shape:SolidMolecular weight:378.51G-5555
CAS:<p>G-5555 is a potent inhibitor of p21-activated kinase 1 (PAK1) (Kis: 3.7 nM and 11 nM for PAK1 and PAK2, respectively).</p>Formula:C25H25ClN6O3Purity:99.76% - 99.84%Color and Shape:SolidMolecular weight:492.96β-Catenin modulator-1
CAS:<p>β-Catenin modulator-1 (IIa-650) is a useful agent in cancer research for modulating β-Catenin [1].</p>Formula:C21H28N2O4SColor and Shape:SolidMolecular weight:404.52JNJ-26076713
CAS:<p>JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.</p>Formula:C29H38N4O3Purity:98%Color and Shape:SolidMolecular weight:490.64β-Catenin modulator-4
CAS:<p>β-Catenin modulator-4 (compound IIa-92), encompassing oxazole and thiazole moieties, acts as a potent and selective modulator of β-Catenin [1].</p>Formula:C21H21ClN2O2SColor and Shape:SolidMolecular weight:400.92Luvixasertib hydrochloride
CAS:<p>CFI-402257 hydrochloride, a highly selective and orally bioavailable inhibitor targeting TTK/Mps1, demonstrates an in vitro IC50 value of 1.7 nM against TTK. This compound exhibits anti-cancer activity [1].</p>Formula:C28H31ClN6O3Color and Shape:SolidMolecular weight:535.04TAS0612
CAS:<p>TAS0612, a novel oral inhibitor of RSK, AKT, and S6K, exhibits broad-spectrum antitumor activity by impeding cell growth [1].</p>Formula:C27H34F3N9O2Purity:98%Color and Shape:SolidMolecular weight:573.61PAK1-IN-1
CAS:<p>PAK1-IN-1: PAK1 inhibitor, IC50 9.8 nM, hinders tumor cell migration and invasion dose-dependently.</p>Formula:C26H20ClN5O2Color and Shape:SolidMolecular weight:469.92Pivanex
CAS:<p>Pivanex, an oral HDAC inhibitor, targets metastasis, angiogenesis, reduces Bcr-Abl protein, and promotes apoptosis.</p>Formula:C10H18O4Purity:≥98%Color and Shape:SolidMolecular weight:202.25ALM301
CAS:<p>ALM301: oral AKT inhibitor targeting AKT1, AKT2, AKT3; blocks AKT phosphorylation, curbs cancer cell growth.</p>Formula:C25H25N3O3Color and Shape:SolidMolecular weight:415.48Dolastatinol
CAS:<p>Dolastatinol, a synthetic analog of Dolastatin 10, serves as a potent low-nanomolar inhibitor of tubulin polymerization.</p>Formula:C43H70N6O7SColor and Shape:SolidMolecular weight:815.12αvβ1 integrin-IN-2
CAS:<p>αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.</p>Formula:C29H38N4O4Purity:98%Color and Shape:SolidMolecular weight:506.64SB-267268
CAS:<p>SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).</p>Formula:C22H24F3N3O4Purity:98%Color and Shape:SolidMolecular weight:451.44Valecobulin hydrochloride
CAS:<p>Valecobulin hydrochloride (CKD-516 hydrochloride) is the valine prodrug and vasoblocker of S516.Cost-effective and quality-assured.</p>Formula:C26H29ClN6O5SPurity:99.52%Color and Shape:SolidMolecular weight:573.06CCT-271850
CAS:<p>CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.</p>Formula:C24H29N7OPurity:98%Color and Shape:SolidMolecular weight:431.53Paluratide
CAS:<p>Paluratide (LUNA18) is a reversible KRAS inhibitor oral , which inhibits cancer cell proliferation by phosphorylating ERK and AKT, RAS with (GEFs).</p>Formula:C73H105F5N12O12Purity:98.70%Color and Shape:SolidMolecular weight:1437.68Levocabastine
CAS:<p>Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.</p>Formula:C26H29FN2O2Color and Shape:SolidMolecular weight:420.52ER degrader 7
CAS:<p>ER degrader 7 (Compound 35t) is a selective degrader of both ERα and ERβ, and possesses activity as a tubulin polymerization inhibitor.</p>Formula:C33H31F4N3O5SSeColor and Shape:SolidMolecular weight:736.63Zaurategrast
CAS:<p>Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.</p>Formula:C26H25BrN4O3Purity:98%Color and Shape:SolidMolecular weight:521.41Phenamacril
CAS:<p>Phenamacril (JS39919) is acyanoacrylate fungicide, has powerful inhibition against Fusarium species, especially to Fusarium graminearum.</p>Formula:C12H12N2O2Purity:99.52%Color and Shape:SolidMolecular weight:216.24HSP90-IN-29
CAS:<p>HSP90-IN-29 (Compound 13), a benzoxazole derivative, serves as a potent and selective HSP-90 inhibitor, exhibiting a low IC50 value of 30 nM. This compound demonstrates significant antitumor activity [1].</p>Formula:C19H20ClN3O4Color and Shape:SolidMolecular weight:389.83Akt-I-1,2
CAS:<p>Akt-I-1,2 is a selective inhibitor of Akt1 and Akt2.</p>Formula:C23H22ClN3Purity:99.95%Color and Shape:SolidMolecular weight:375.893,4',5-Trismethoxybenzophenone
CAS:<p>3,4',5-Trismethoxybenzophenone (compound 16a) is an effective inhibitor of tubulin assembly, demonstrating a half-maximal inhibitory concentration (IC 50) of 2.6 µM [1].</p>Formula:C16H16O4Color and Shape:SolidMolecular weight:272.3GRP78-IN-2
CAS:<p>GRP78-IN-2 inhibits surface GRP78, showing anti-angiogenic and anti-cancer properties, sparing normal cells.</p>Formula:C29H29NO6Color and Shape:SolidMolecular weight:487.54Tirofiban HCl
CAS:<p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>Formula:C22H37ClN2O5SPurity:98%Color and Shape:SolidMolecular weight:477.06Iroxanadine sulfate
CAS:<p>Iroxanadine sulfate is a MAPK p38 inhibitor potentially for the treatment of atherosclerosis.</p>Formula:C14H22N4O5SColor and Shape:SolidMolecular weight:358.41Integrin Antagonists 27
CAS:<p>Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.</p>Formula:C24H20N4O5Color and Shape:SolidMolecular weight:444.44PAK4-IN-1
CAS:<p>PAK4-IN-1: selective, potent oral PAK4 inhibitor; stable in acid/neutral; shows strong anti-tumor in vivo.</p>Formula:C26H30ClN7O5Color and Shape:SolidMolecular weight:556.01Porcn-IN-2
CAS:<p>Porcn-IN-2 (Example 107) is a potent Wnt pathway inhibitor, exhibiting an IC50 of 0.05 nM.</p>Formula:C24H17F3N6OColor and Shape:SolidMolecular weight:462.43αvβ6 integrin inhibitor 2
CAS:<p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>Formula:C21H30N4O3Purity:98%Color and Shape:SolidMolecular weight:386.49Risvodetinib
CAS:<p>Risvodetinib: potent inhibitor of protein tyrosine kinases c-Abl1, c-Abl2, and c-kit.</p>Formula:C33H34N8O2Color and Shape:SolidMolecular weight:574.68Solitomab
CAS:<p>Solitomab (AMG 110) is a bispecific antibody targeting CD3 and EpCAM, used in uterine/ovarian carcinosarcoma research.</p>Color and Shape:LiquidLitronesib
CAS:<p>Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.</p>Formula:C23H37N5O4S2Purity:98%Color and Shape:SolidMolecular weight:511.7Tubulin inhibitor 25
CAS:<p>Potent Tubulin inhibitor 25: IC50 0.98 μM, blocks HT29 cell growth, hinders cell migration & microtubule formation, anti-angiogenic.</p>Formula:C26H22O8Color and Shape:SolidMolecular weight:462.45β-catenin-IN-6
CAS:<p>β-Catenin-IN-6 is an inhibitor of the canonical Wnt/β-catenin signaling pathway, effectively impeding the proliferation of human colorectal cancer cells and</p>Formula:C22H19ClN6OColor and Shape:SolidMolecular weight:418.88KIF18A-IN-7
CAS:<p>KIF18A-IN-7 is an orally active inhibitor targeting KIF18A, demonstrating potent inhibition with an IC50 value of 9.4 nM against the microtubule-dependent</p>Formula:C27H35N3O5S2Color and Shape:SoildMolecular weight:545.71MAO A/HSP90-IN-1
CAS:<p>MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of 1.77 μM in glioblastoma (GBM) GL26 cells and 0.019 μM against HSP90α.</p>Formula:C24H29ClN2O4Purity:98%Color and Shape:SolidMolecular weight:444.95LY2780301
CAS:<p>LY2780301, an oral Akt (protein kinase B) inhibitor, may hinder cancer cell growth and trigger apoptosis by blocking the PI3K/Akt pathway.</p>Formula:C25H27F4N7OColor and Shape:SolidMolecular weight:517.52KSP-IA
CAS:<p>KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.</p>Formula:C21H22F2N2OPurity:98%Color and Shape:SolidMolecular weight:356.41Lotrafiban hydrochloride
CAS:<p>Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.</p>Formula:C23H33ClN4O4Color and Shape:SolidMolecular weight:464.99
