Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
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CK-869
CAS:388592-44-7
CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools …
Formula:
C17H16BrNO3S
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
394.28
Ref: TM-T5860
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 102.00 € | ||
| 50mg | 164.00 € | ||
| 100mg | 255.00 € | ||
| 200mg | 364.00 € | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Cyclo(-RGDfK) TFA
CAS:500577-51-5
Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).
Formula:
C29H42F3N9O9
Purity:
99.54%
Color and Shape:
Solid
Molecular weight:
717.69
Ref: TM-T6812L
| 1mg | 51.00 € | ||
| 5mg | 98.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 384.00 € | ||
| 1mL*10mM (DMSO) | 166.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Rocaglamide
CAS:84573-16-0
Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.
Formula:
C29H31NO7
Purity:
95.32% - 98.46%
Color and Shape:
Solid
Molecular weight:
505.56
Ref: TM-TQ0131
| 1mg | 278.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Degrasyn
CAS:856243-80-6
Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S …
Formula:
C19H18BrN3O
Purity:
98.32% - 99.98%
Color and Shape:
Solid
Molecular weight:
384.27
Ref: TM-T6300
| 5mg | 63.00 € | ||
| 10mg | 100.00 € | ||
| 25mg | 195.00 € | ||
| 50mg | 352.00 € | ||
| 100mg | 522.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Albendazole sulfoxide
CAS:54029-12-8
Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.
Formula:
C12H15N3O3S
Purity:
98.04%
Color and Shape:
White To Off-White Powder
Molecular weight:
281.33
Ref: TM-T6372
| 50mg | 48.00 € | ||
| 100mg | 71.00 € | ||
| 200mg | 91.00 € | ||
| 500mg | 152.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
CWHM-12
CAS:1564286-55-0
CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).
Formula:
C26H32BrN5O6
Purity:
98.05% - 98.5%
Color and Shape:
Solid
Molecular weight:
590.47
Ref: TM-TQ0250
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 362.00 € | ||
| 100mg | 538.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Batatasin III
CAS:56684-87-8
Batatasin III inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition and FAK-AKT …
Formula:
C15H16O3
Purity:
99.16%
Color and Shape:
Solid
Molecular weight:
244.29
Ref: TM-TN1433
| 1mg | 103.00 € | ||
| 2mg | 155.00 € | ||
| 5mg | 254.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 592.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
PF-04929113 Mesylate
CAS:1173111-67-5
PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: …
Formula:
C26H34F3N5O7S
Purity:
99% - 99.46%
Color and Shape:
Solid
Molecular weight:
617.63
Ref: TM-T4342
| 1mg | 77.00 € | ||
| 2mg | 99.00 € | ||
| 5mg | 158.00 € | ||
| 10mg | 285.00 € | ||
| 25mg | 413.00 € | ||
| 50mg | 608.00 € | ||
| 100mg | 868.00 € | ||
| 500mg | 1,737.00 € | ||
| 1mL*10mM (DMSO) | 230.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Loureirin A
CAS:119425-89-7
Loureirin A inhibits platelet aggregation and PI3K/Akt signaling, promotes hair follicle repair, and has anti-fibrotic …
Formula:
C17H18O4
Purity:
99.83% - 99.84%
Color and Shape:
Solid
Molecular weight:
286.32
Ref: TM-T5S0896
| 1mg | 74.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 205.00 € | ||
| 25mg | 347.00 € | ||
| 50mg | 510.00 € | ||
| 100mg | 728.00 € | ||
| 500mg | 1,457.00 € | ||
| 1mL*10mM (DMSO) | 205.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
ABT-751
CAS:141430-65-1
ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, …
Formula:
C18H17N3O4S
Purity:
98.84% - 99.48%
Color and Shape:
Solid
Molecular weight:
371.41
Ref: TM-T1758
| 5mg | 48.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 273.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Corosolic acid
CAS:4547-24-4
Corosolic acid inhibits angiogenesis, suppresses FAK, fights various cancers, induces apoptosis, and degrades β-catenin.
Formula:
C30H48O4
Purity:
99.46% - 99.5%
Color and Shape:
Fine-Brown Yellow Powder
Molecular weight:
472.7
Ref: TM-T3391
| 5mg | 46.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 166.00 € | ||
| 100mg | 237.00 € | ||
| 200mg | 361.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Nocodazole
CAS:31430-18-9
Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.
Formula:
C14H11N3O3S
Purity:
98% - 99.91%
Color and Shape:
Physical Description White Powder (Ntp 1992)
Molecular weight:
301.32
Ref: TM-T2802
| 5mg | 36.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 97.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 276.00 € | ||
| 200mg | 412.00 € | ||
| 500mg | 669.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
SB-743921 hydrochloride
CAS:940929-33-9
SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 …
Formula:
C31H34Cl2N2O3
Purity:
95.58% - ≥95%
Color and Shape:
Solid
Molecular weight:
553.52
Ref: TM-T2255
| 1mg | 42.00 € | ||
| 5mg | 105.00 € | ||
| 10mg | 161.00 € | ||
| 25mg | 274.00 € | ||
| 50mg | 424.00 € | ||
| 100mg | 649.00 € | ||
| 500mg | 1,476.00 € | ||
| 1mL*10mM (DMSO) | 129.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Rebastinib
CAS:1020172-07-9
DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and …
Formula:
C30H28FN7O3
Purity:
99.53% - 99.84%
Color and Shape:
Solid
Molecular weight:
553.59
Ref: TM-T2640
| 2mg | 47.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 247.00 € | ||
| 100mg | 370.00 € | ||
| 200mg | 557.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
AT7867
CAS:857531-00-1
AT7867 inhibits Akt1/2/3 & p70S6K/PKA (IC50: 32/17/47 nM & 85/20 nM), minimal effect beyond AGC …
Formula:
C20H20ClN3
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
337.85
Ref: TM-T6304
| 2mg | 43.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 203.00 € | ||
| 100mg | 302.00 € | ||
| 200mg | 436.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Cyclo(RGDyK) trifluoroacetate
CAS:250612-42-1
Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
Formula:
C31H43F6N9O12
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
847.72
Ref: TM-T6813
| 1mg | 45.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 454.00 € | ||
| 100mg | 661.00 € | ||
| 1mL*10mM (DMSO) | 134.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
KX2-361
CAS:897016-26-1
KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival …
Formula:
C24H24FN3O2
Purity:
98.52% - 99.86%
Color and Shape:
Solid
Molecular weight:
405.46
Ref: TM-T9411
| 1mg | 79.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 230.00 € | ||
| 25mg | 376.00 € | ||
| 50mg | 529.00 € | ||
| 100mg | 710.00 € | ||
| 200mg | 912.00 € | ||
| 1mL*10mM (DMSO) | 177.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
ZIP acetate(863987-12-6 free base)
ZIP acetate inhibits PKMζ (protein kinase Mζ), affecting LTP maintenance and spatial memory, with an …
Formula:
C92H158N30O19
Purity:
94.68%
Color and Shape:
Solid
Molecular weight:
1988.43
Ref: TM-TP1924L1
| 1mg | 85.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 411.00 € | ||
| 50mg | 578.00 € | ||
| 100mg | 782.00 € | ||
| 200mg | 1,037.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
BIO-1211
CAS:187735-94-0
BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 …
Formula:
C36H48N6O9
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
708.8
Ref: TM-T21868
| 1mg | 110.00 € | ||
| 2mg | 163.00 € | ||
| 5mg | 271.00 € | ||
| 10mg | 435.00 € | ||
| 25mg | 702.00 € | ||
| 50mg | 926.00 € | ||
| 100mg | 1,295.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Pifithrin-μ
CAS:64984-31-2
Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.
Formula:
C8H7NO2S
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
181.21
Ref: TM-T6210
| 5mg | 46.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 102.00 € | ||
| 50mg | 148.00 € | ||
| 100mg | 214.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
