CAS 4547-24-4

Corosolic acid

Description:

Corosolic acid, with the CAS number 4547-24-4, is a naturally occurring triterpenoid compound primarily found in the leaves of the Lagerstroemia speciosa plant, commonly known as the banaba tree. This compound is characterized by its pentacyclic structure, which contributes to its biological activity. Corosolic acid is known for its potential health benefits, including anti-diabetic properties, as it may help regulate blood glucose levels by enhancing insulin sensitivity. Additionally, it exhibits antioxidant and anti-inflammatory effects, making it of interest in various therapeutic applications. The compound is typically extracted from plant sources and can be found in dietary supplements aimed at promoting metabolic health. Its solubility is generally low in water but can be dissolved in organic solvents, which is important for its extraction and formulation in products. Overall, corosolic acid is a compound of significant interest in both pharmacological research and natural product chemistry due to its diverse biological activities.

Formula: C₃₀H₄₈O₄

InChI: InChI=1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,1-7H3,(H,33,34)/t17-,18+,20-,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1

InChI key: InChIKey=HFGSQOYIOKBQOW-ZSDYHTTISA-N

SMILES: C[C@]12[C@@]3(C)C([C@]4([C@@](C(O)=O)(CC3)CC[C@@H](C)[C@@H]4C)[H])=CC[C@@]1([C@]5(C)[C@@](CC2)(C(C)(C)[C@@H](O)[C@H](O)C5)[H])[H]

Synonyms:

• (2Alpha,3Beta)-2,3-Dihydroxyurs-12-En-28-Oic Acid
• (2Alpha,3Beta,5Xi,18Alpha)-2,3-Dihydroxyurs-12-En-28-Oic Acid
• (2α,3β)-2,3-Dihydroxyurs-12-en-28-oic acid
• 2alpha-Hydroxyursolic acid
• 2α,2β,-Dihydroxy-12-en-28-ursolic acid
• 2α,3β-Dihydroxy ursolic acid
• 2α,3β-Dihydroxylursolic acid
• 2α,3β-Dihydroxyurs-12-en-28-oic acid
• 2α-Hydroxyursolic acid
• Colosic acid
• Colosolic acid
• Corsolic acid
• Glucosol
• Urs-12-en-28-oic acid, 2,3-dihydroxy-, (2α,3β)-

Corosolic Acid

CAS: 4547-24-4

Formula: C₃₀H₄₈O₄

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 472.71

Ref: 3B-C3921

Corosolic Acid

CAS: 4547-24-4

Carboxylic acids w/ alcohol function but w/o other oxygen function and their derivatives, nesoi

Formula: C₃₀H₄₈O₄

Color and Shape: White Powder

Molecular weight: 472.35526

Ref: 45-1148737

Corosolic Acid

CAS: 4547-24-4

Corosolic Acid

Formula: C₃₀H₄₈O₄

Purity: 0.98

Molecular weight: 472.7

Ref: 54-OR1022912

Corosolic acid

CAS: 4547-24-4

Corosolic acid

Formula: C₃₀H₄₈O₄

Purity: ≥98%

Molecular weight: 472.7

Ref: 54-BUP10740

Corosolic acid

CAS: 4547-24-4

Formula: C₃₀H₄₈O₄

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 472.70

Ref: 7W-GL8496

Corosolic acid

CAS: 4547-24-4

Formula: C₃₀H₄₈O₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 472.6997

Ref: IN-DA00DEAY

Corosolic acid

CAS: 4547-24-4

Corosolic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₃₀H₄₈O₄

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 472.71

Ref: 11-2318S

Corosolic acid (Standard)

CAS: 4547-24-4

Corosolic acid (Standard) is a reference standard for research and analysis in studies involving Corosolic acid. Corosolic acid (Colosic acid) contains anti-angiogenic activity that can suppress FAK signaling induced by angiopoietin-1. Corosolic acid exerts anticancer activities against HCC, colon, and colorectal Y cells, by inducing apoptosis and promoting the N-terminal phosphorylation and subsequent proteasomal degradation of β-catenin.

Formula: C₃₀H₄₈O₄

Molecular weight: 472.6997

Ref: TM-TMSM-2290

Corosolic acid

CAS: 4547-24-4

Corosolic acid (CRA), a constituent of banaba leaves, has been reported to have anti-inflammatory and hypoglycemic activities, it can ameliorate hypertension, abnormal lipid metabolism, and oxidative stress as well as the inflammatory state in SHR-cp rats, suggests CRA can be beneficial for preventing atherosclerosis-related diseases.

Formula: C₃₀H₄₈O₄

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 472.71

Ref: BP-BP0395

(2a,3b)-2,3-Dihydroxy-urs-12-en-28-oic Acid

Controlled Product

CAS: 4547-24-4

Applications (2α,3β)-2,3-Dihydroxy-urs-12-en-28-oic Acid influences inflammatory gene expression regarding inflammatory bowel disease. In addition, its extracted from the plants Gentiana farreri and shows anti-tumor activity
References Mueller, D. et al.: Food Chem., 139, 339 (2013); Thilakarathna, S. et al.: Food Chem., 138, 463 (2013); Yang, A. et al.: Adv. Mat. Res., 554, 1682 (2012);

Formula: C₃₀H₄₈O₄

Color and Shape: Neat

Molecular weight: 472.7

Ref: TR-C695600

Corosolic acid

CAS: 4547-24-4

Corosolic acid inhibits angiogenesis, suppresses FAK, fights various cancers, induces apoptosis, and degrades β-catenin.

Formula: C₃₀H₄₈O₄

Purity: 99.46% - 99.85%

Color and Shape: White Solid

Molecular weight: 472.6997

Ref: TM-T3391

Corosolic acid

CAS: 4547-24-4

Carboxylic acid with alcohol function

Formula: C₃₀H₄₈O₄

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 472.71

Ref: 5G-80065

Corosolic acid

CAS: 4547-24-4

Formula: C₃₀H₄₈O₄

Molecular weight: 472.7

Ref: BE-RMT12844