Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1644 products for "Cytoskeletal Signaling".
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Cystatin B agonist 1
Cystatin Bagonist 1 is an orally active inhibitor of MMP-2/9. It suppresses U87 and T98G cells with IC50 values of 3.95 μM and 3.43 μM, respectively. Cystatin Bagonist 1 induces S-phase cell cycle arrest in MG cells and inhibits their angiogenesis, migration, and invasion. Additionally, it hinders tumor growth in U87 MG xenograft models. This compound is applicable for research in malignant glioma (MG).Color and Shape:Odour SolidFKKSFKL-NH2
CAS:FKKSFKL-NH2 is a selective peptide for protein kinase C, employed in biochemical research [1].Formula:C45H73N11O8Color and Shape:SolidMolecular weight:896.13BCR-ABL-IN-3
CAS:BCR-ABL-IN-3 irreversibly inhibits Bcr-Abl with <100 nM IC50, showing significant anti-cancer effects.Formula:C20H17ClF2N4O3SColor and Shape:SolidMolecular weight:466.89Fibrinogen Binding Inhibitor Peptide
CAS:Synthetic dodecapeptide mimics human fibrinogen g-chain, inhibits platelet receptor (residues 400-411).Formula:C50H80N18O16Purity:98%Color and Shape:SolidMolecular weight:1189.28BRM/BRG1 ligand 3
CAS:BRM/BRG1 ligand 3 is a target protein ligand utilized in the synthesis of PROTAC BRM/BRG1 degrader-3.Formula:C19H24N6OColor and Shape:SolidMolecular weight:352.43Fradafiban hydrochloride
Fradafiban (BIBU-52) is a nonpeptide GPIIb/IIIa antagonist with Kd 148 nM for human platelets.Formula:C20H22ClN3O4Color and Shape:SolidMolecular weight:403.86CCT 031374 hydrobromide
CAS:CCT 031374 hydrobromide is a TCF/β-catenin inhibitor with antitumor activities.Formula:C23H20BrN3OPurity:99.50%Color and Shape:Yellow SolidMolecular weight:434.328Ref: TM-T21685
1mg35.00€5mg67.00€1mL*10mM (DMSO)82.00€10mg100.00€25mg197.00€50mg313.00€100mg447.00€200mg587.00€Microtubule destabilizing agent-1
CAS:Compound 12b is a hydroxamic acid-based MDA with stable metabolism, high bioavailability, and strong antitumor properties.Formula:C22H26N4O4Color and Shape:SolidMolecular weight:410.47MS15
MS15, a selective AKT PROTAC degrader, inhibits AKT1/2/3 with IC50s: 798 nM, 90 nM, 544 nM.Formula:C64H79N11O5SColor and Shape:SolidMolecular weight:1114.45Pamidronate monosodium
CAS:Pamidronate monosodium is a bisphosphonate.Formula:C3H10NNaO7P2Color and Shape:SolidMolecular weight:257.05NRX-1933
CAS:NRX-1933 is a molecular glue and enhances the interaction between an oncogenic transcription factor, β-Catenin, and its cognate E3 ligase, SCFβ-TrCP.Formula:C14H9F3N6O2Purity:99.93%Color and Shape:SolidMolecular weight:350.26Ref: TM-T60031
1mg100.00€5mg236.00€1mL*10mM (DMSO)259.00€10mg378.00€25mg640.00€50mg893.00€100mg1,189.00€para-amino-Blebbistatin
CAS:para-amino-Blebbistatin is a water-soluble, stable, non-phototoxic inhibitor of non-muscle myosin II, with enhanced properties over blebbistatin.Formula:C18H17N3O2Color and Shape:SolidMolecular weight:307.353Tyrosine kinase-IN-8
Tyrosine kinase-IN-8 (compound 4e) is a BCR‐ABL1 tyrosine kinase inhibitor (TKI) exhibiting antiproliferative activity against the chronic myeloid leukemia (CML) cell line K562, with a CC50 of 0.8 µM. Tyrosine kinase-IN-8 is applicable for research in chronic leukemia.Formula:C31H21F2N7O2Color and Shape:SolidMolecular weight:561.17248H2-Gamendazole
CAS:H2-Gamendazole: inhibits spermatogenesis, cancer therapy, targets heat shock proteins & EF1α, regulates Hsp90.Formula:C18H13Cl2F3N2O2Purity:97.39%Color and Shape:SolidMolecular weight:417.21Ref: TM-T72076
1mg73.00€5mg180.00€1mL*10mM (DMSO)203.00€10mg269.00€25mg477.00€50mg642.00€100mg880.00€200mg1,161.00€KTC1101
CAS:KTC1101 is a pan-PI3K inhibitor with antiproliferative and anticancer activities, reducing phosphorylation of downstream AKT and mTOR.Formula:C21H26F2N8O3Purity:98.75%Color and Shape:Gray SolidMolecular weight:476.48Ref: TM-T89831
1mg75.00€5mg149.00€1mL*10mM (DMSO)149.00€10mg235.00€25mg470.00€50mg758.00€100mg1,215.00€(8R)-8-Hydroxyepoxyboetirane A
(8R)-8-Hydroxyepoxyboetirane A is a neuroactivating compound that interacts with PKCδ-C1B. This compound binds into the PKC enzyme pocket through hydrogen bonds with glycine-253, leucine-251, and threonine-242. It induces the release of NRG1 and promotes the differentiation of neural stem cells into neurons. (8R)-8-Hydroxyepoxyboetirane A holds potential for research into nervous system disorders.Color and Shape:Odour SolidKIF18A-IN-15
CAS:KIF18A-IN-15 (Compound Example 36) is a KIF18A inhibitor, available in two forms, EX36-A and its enantiomer EX36-B, both with an IC50 range of 0.01-0.1 μM. These compounds inhibit the viability of OVCAR-3 cells, with IC50 values of 0.01-0.1 μM for EX36-A and 0-0.01 μM for EX36-B. KIF18A-IN-15 is applicable in research on tumors, including colon, breast, and lung cancers.Formula:C25H33F3N6O5SColor and Shape:SolidMolecular weight:586.63Tubulin inhibitor 45
Tubulin inhibitor 45 (compound 5) functions as an inhibitor of the active site of tubulin. It exhibits IC50 values of 11 μM for MCF7 cancer cells and 13 μM for HePG2 cancer cells.Formula:C19H18N2O2SColor and Shape:SolidMolecular weight:338.1089PKC β pseudosubstrate
CAS:Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM).Formula:C177H294N62O38S3Purity:98%Color and Shape:SolidMolecular weight:3994.84PKCα (C2-4) inhibitor peptide
PKCα (C2-4) inhibitor peptide is a specific antagonist to PKCα that impedes the α1A-adrenoreceptor agonist A-61603 [1] from inhibiting I_Kr.Formula:C47H74N14O17Purity:98%Color and Shape:SolidMolecular weight:1107.17
