Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
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JH-VIII-157-02
CAS:1639422-97-1
JH-VIII-157-02 inhibits ALK, specifically EML4-ALK variants, with IC50s of 2 nM.
Formula:
C28H27N5O2
Purity:
98.02%
Color and Shape:
Solid
Molecular weight:
465.55
Ref: TM-T15612
| 1mg | 116.00 € | ||
| 5mg | 240.00 € | ||
| 10mg | 358.00 € | ||
| 25mg | 558.00 € | ||
| 50mg | 753.00 € | ||
| 100mg | 1,035.00 € | ||
| 1mL*10mM (DMSO) | 246.00 € |
Estimated delivery in United States, on Friday 16 May 2025
SS28
CAS:141172-08-9
SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.
Formula:
C18H20O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
284.35
Ref: TM-T13901
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 16 May 2025
ZINC00640089
CAS:667880-11-7
ZINC00640089: Selective LCN2 inhibitor; curbs SUM149 cell growth and AKT activity; useful for IBC research.
Formula:
C20H13F3N2O2
Purity:
98.13% - 99.27%
Color and Shape:
Liquid
Molecular weight:
370.32
Ref: TM-T72968
| 1mg | 66.00 € | ||
| 5mg | 144.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 311.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 588.00 € |
Estimated delivery in United States, on Friday 16 May 2025
DM1-SMe
CAS:138148-68-2
DM1-SMe (DM1-SSMe) potently inhibits microtubules, 3-10x stronger than Maytansine with IC50s of 0.003-0.01 nM in …
Formula:
C36H50ClN3O10S2
Purity:
97.19%
Color and Shape:
Solid
Molecular weight:
784.38
Ref: TM-T21408
| 1mg | 35.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 259.00 € | ||
| 50mg | 375.00 € | ||
| 100mg | 545.00 € | ||
| 1mL*10mM (DMSO) | 104.00 € |
Estimated delivery in United States, on Friday 16 May 2025
OSIP-486823
CAS:200803-37-8
OSIP-486823(CP248) is a novel and potent microtubule disruptor with affinity for both protein kinase G …
Formula:
C29H28FNO4
Purity:
98.59%
Color and Shape:
Solid
Molecular weight:
473.54
Ref: TM-T13807
| 1mg | 537.00 € | ||
| 5mg | 1,121.00 € | ||
| 10mg | 1,539.00 € | ||
| 25mg | 2,270.00 € | ||
| 50mg | 3,087.00 € |
Estimated delivery in United States, on Friday 16 May 2025
PF-2771
CAS:2070009-55-9
PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.
Formula:
C29H36ClN5O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
554.08
Ref: TM-T12434
| 100mg | 1,415.00 € |
Estimated delivery in United States, on Friday 16 May 2025
AZ13705339
CAS:2016806-57-6
AZ13705339 is an effective inhibitor of PAK1 with an IC50 of 0.33 nM and a …
Formula:
C33H36FN7O3S
Purity:
98.57%
Color and Shape:
Solid
Molecular weight:
629.75
Ref: TM-T26704
| 2mg | 47.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 338.00 € | ||
| 100mg | 543.00 € |
Estimated delivery in United States, on Friday 16 May 2025
CCT128930
CAS:885499-61-6
'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'
Formula:
C18H20ClN5
Purity:
99.07% - 99.18%
Color and Shape:
Solid
Molecular weight:
341.84
Ref: TM-T6303
| 2mg | 42.00 € | ||
| 5mg | 65.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 273.00 € | ||
| 100mg | 409.00 € | ||
| 200mg | 652.00 € | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Friday 16 May 2025
JB002
CAS:30408-07-2
JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM.
Formula:
C18H15NO3
Purity:
99.02%
Color and Shape:
Soild
Molecular weight:
293.32
Ref: TM-T72023
| 1mg | 77.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 264.00 € | ||
| 25mg | 535.00 € | ||
| 50mg | 747.00 € | ||
| 100mg | 1,035.00 € | ||
| 500mg | 2,072.00 € | ||
| 1mL*10mM (DMSO) | 180.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Nilotinib hydrochloride
CAS:923288-95-3
Nilotinib HCl (AMN-107 HCl), an oral Bcr-Abl inhibitor, targets neuroinflammation, cognitive issues, and chronic myelogenous …
Formula:
C28H23ClF3N7O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
565.98
Ref: TM-T22378
| 5mg | 48.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 136.00 € | ||
| 100mg | 198.00 € | ||
| 500mg | 563.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Cevipabulin
CAS:849550-05-6
Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to …
Formula:
C18H18ClF5N6O
Purity:
99.53%
Color and Shape:
Solid
Molecular weight:
464.82
Ref: TM-T10772
| 1mg | 35.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Friday 16 May 2025
β-glycosidase-IN-1
CAS:176485-27-1
β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.
Formula:
C13H23NO5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
273.33
Ref: TM-T13478
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 16 May 2025
PF-06651481-00
CAS:1391063-17-4
PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.
Formula:
C26H29Cl2N5O3
Purity:
97.57%
Color and Shape:
Solid
Molecular weight:
530.45
Ref: TM-T28374
| 1mg | 42.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 127.00 € |
Estimated delivery in United States, on Friday 16 May 2025
BCR-ABL-IN-1
CAS:188260-50-6
BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the …
Formula:
C23H21F4N5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
459.44
Ref: TM-T10488
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 16 May 2025
CID-663143
CAS:578723-96-3
CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.
Formula:
C19H18N4O2S
Purity:
99.56% - 99.68%
Color and Shape:
Solid
Molecular weight:
366.44
Ref: TM-T23889
| 1mg | 77.00 € | ||
| 5mg | 158.00 € | ||
| 10mg | 225.00 € | ||
| 25mg | 338.00 € | ||
| 50mg | 475.00 € | ||
| 100mg | 638.00 € | ||
| 200mg | 845.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Friday 16 May 2025
para-Nitroblebbistatin
CAS:1621326-32-6
para-Nitroblebbistatin is a non-cytotoxic, non-fluorescent, photostable, and specific inhibitor of myosin II.Cost-effective and quality-assured.
Formula:
C18H15N3O4
Purity:
100% - 99.92%
Color and Shape:
Solid
Molecular weight:
337.33
Ref: TM-T12360
| 1mg | 87.00 € | ||
| 5mg | 212.00 € | ||
| 10mg | 316.00 € | ||
| 25mg | 512.00 € | ||
| 50mg | 695.00 € | ||
| 100mg | 940.00 € | ||
| 200mg | 1,264.00 € | ||
| 1mL*10mM (DMSO) | 215.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Dihydrocytochalasin B
CAS:39156-67-7
Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.
Formula:
C29H39NO5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
481.62
Ref: TM-T11042
| 1mg | 349.00 € | ||
| 5mg | 1,378.00 € | ||
| 500µg | 185.00 € |
Estimated delivery in United States, on Friday 16 May 2025
AMP-PCP disodium
CAS:7414-56-4
AMP-PCP disodium is an ATP analogue with binding affinity to the N-terminal domain of Hsp90, …
Formula:
C11H16N5Na2O12P3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
549.17
Ref: TM-T13547L
| 1mg | 70.00 € | ||
| 5mg | 187.00 € | ||
| 10mg | 279.00 € | ||
| 25mg | 472.00 € | ||
| 50mg | 658.00 € | ||
| 100mg | 933.00 € | ||
| 500mg | 1,863.00 € |
Estimated delivery in United States, on Friday 16 May 2025
αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).
Formula:
C28H35F3N6O8S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
672.67
Ref: TM-T13473L
| 25mg | 1,054.00 € | ||
| 50mg | 1,381.00 € | ||
| 100mg | 1,882.00 € | ||
| 200mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Friday 16 May 2025
S-methyl DM1
CAS:912569-84-7
S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 …
Formula:
C36H50ClN3O10S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
752.31
Ref: TM-T12805
| 25mg | 1,586.00 € | ||
| 50mg | 2,072.00 € | ||
| 100mg | 2,660.00 € |
Estimated delivery in United States, on Friday 16 May 2025
