Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1590 products of "Cytoskeletal Signaling"
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Sibrafiban
CAS:Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.Formula:C20H28N4O6Color and Shape:SolidMolecular weight:420.46Tubulin polymerization-IN-25
CAS:Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) & FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.Formula:C24H18N2O3SColor and Shape:SolidMolecular weight:414.48YM-1
CAS:YM-1, a stable MKT-077 analog, inhibits Hsp70 orally, kills HeLa cells, and boosts p53 and p21 proteins.Formula:C20H20ClN3OS2Color and Shape:SolidMolecular weight:417.98Tubulin polymerization-IN-10
CAS:Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.Formula:C18H21NO6SColor and Shape:SolidMolecular weight:379.43AKT-IN-8
CAS:AKT-IN-8 is a potent inhibitor of AKT, acting on AKT1 (IC50: 4.46 nM), AKT2 (IC50: 2.44 nM) and AKT3 (IC50: 9.47 nM).Formula:C22H25ClN6O3Color and Shape:SolidMolecular weight:456.93AKT-IN-5
CAS:AKT-IN-5, an Akt inhibitor, targets Akt1/Akt2 with IC50s: 450/400 nM.Formula:C23H20N4O2Color and Shape:SolidMolecular weight:384.43Zalunfiban
CAS:RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.Formula:C16H18N8O2SColor and Shape:SolidMolecular weight:386.43Zarilamide
CAS:Zarilamide disrupts microtubules, inhibiting mitosis in Phytophthora capsici zoospore cysts.Formula:C11H11ClN2O2Color and Shape:SolidMolecular weight:238.67Tubulin polymerization-IN-20
CAS:Tubulin aggregation-IN-20, a potent inhibitor, may be studied for breast and drug-resistant colon cancers.Formula:C25H24FNO5Color and Shape:SolidMolecular weight:437.46Tubulin inhibitor 27
CAS:DYT-1 Tubulin inhibitor 27, IC50: 25.6 μM, hinders tubulin polymerization, displays anti-angiogenic and antitumor effects.Formula:C21H19NO4Color and Shape:SolidMolecular weight:349.38Microtubule inhibitor 5
CAS:Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.Formula:C22H15FN2O4Color and Shape:SolidMolecular weight:390.36Tubulin/MMP-IN-1
Tubulin/MMP-IN-1 inhibits tubulin, MMP, and cancer cell growth; disrupts cell cycles and induces apoptosis.Formula:C38H44NO9PColor and Shape:SolidMolecular weight:689.73HSP90-IN-20
CAS:HSP90-IN-20, a potent inhibitor of HSP90, exhibits an IC50 of ≤10 μM, indicating its potential application in cancer research.Formula:C26H32N4O4Color and Shape:SolidMolecular weight:464.56BuChE-IN-5
CAS:"BuChE-IN-5 is a potent inhibitor with an IC50 of 1.94 μM and shows promise for Alzheimer's research."Formula:C25H35N3Color and Shape:SolidMolecular weight:377.57CHMFL-ABL-053
CAS:CHMFL-ABL-053: potent, selective BCR-ABL/SRC/p38 inhibitor (IC50: 70/90/62 nM). Orally available, potential CML drug.Formula:C28H26F3N7O2Color and Shape:SolidMolecular weight:549.55CRT0066854 hydrochloride
CAS:CRT0066854 HCl inhibits atypical PKCs; IC50: PKCι 132 nM, PKCζ 639 nM, ROCK-II 620 nM.Formula:C24H27Cl2N5SPurity:99.63%Color and Shape:SolidMolecular weight:488.48Ref: TM-T10888
1mg57.00€5mg122.00€1mL*10mM (DMSO)146.00€10mg192.00€25mg324.00€50mg459.00€100mg642.00€200mg888.00€BMD4503-2
CAS:BMD4503-2 is a competitive inhibitor of the LRP5/6-sclerostin complex that restores the activity of the Wnt/β-catenin signaling pathway cancer.Formula:C26H21N5O3SPurity:99.18%Color and Shape:SolidMolecular weight:483.54Elsibucol
CAS:Elsibucol (AGI 1096) is a VCAM1 inhibitor for the study of organ transplant rejection.Elsibucol is a metabolically stable propanol derivative with antioxidant,Formula:C35H54O4S2Purity:99.41%Color and Shape:SolidMolecular weight:602.93DZ2002
CAS:DZ2002: Oral, reversible SAHH inhibitor (Ki=17.9 nM), low-toxicity, immunosuppressive, counters dermal fibrosis, used in autoimmune research.Formula:C10H13N5O3Purity:99.91%Color and Shape:SolidMolecular weight:251.24Ref: TM-T11134
1mg105.00€5mg250.00€1mL*10mM (DMSO)268.00€10mg371.00€25mg610.00€50mg858.00€100mg1,153.00€500mg2,313.00€TCS 2210
CAS:TCS 2210 promotes neuronal differentiation in stem cells, boosting β-III tubulin and enolase markers.Formula:C18H17N3O3Purity:98.62%Color and Shape:SolidMolecular weight:323.35Ref: TM-T23446
1mg86.00€2mg116.00€5mg172.00€1mL*10mM (DMSO)177.00€10mg259.00€25mg444.00€50mg610.00€100mg867.00€500mg1,738.00€
