Miscellaneous Organic Molecules with Isotopical Substitutions

Applications 2,4,6-Trimethylphenol-d11 (CAS# 362049-45-4) is a useful isotopically labeled research compound.

Applications Bedaquiline-d6 is the labelled analog of Bedaquiline, a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);

Stability Light Sensitive, Temperature Sensitive
Applications Labelled 9-cis Retinol Acetate (R252100). Retinal derivative for treatment of visual disorders. Vitamin A derivative.
References Ruiz, A., et al.: J. Biol. Chem., 274, 3834 (1999), van Hooser, J., et al.: J. Biol. Chem., 277, 19173 (2002), Haeseleer, F., et al.: J. Biol. Chem., 277, 45537 (2002).

Applications Labelled 1-Oleoyl-2-linolenoyl-3-chloropropanediol (O530400). New lipids in food protein hydrolyzates.

Applications Labelled R-Ketoprofen (K200806). Anti-inflammatory; analgesic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),

Applications Ethyl Acetoacetate-13C4 is the isotope labelled analog of Ethyl Acetoacetate, an chemical intermediate used in the production of various analgesics, antibiotics and antimalarial agents.
References Mutti, F.G., et al.: Adv. Syn. Cata., 354, 3409 (2012); Subudhi, B., et al.: Bull. Chem. Soc., Ethiopia., 26, 455 (2012);

Applications 2-Chloroethanol is used in the preparation of TTFTT (tetrathiafulvalene-2,3,6,7-tetrathiolate) and important building block in TTF syntheis. In addition, it is used in the synthesis of vinyltriazoles. This is the labeled analog.
Dangerous Goods Info This compound is forbidden to ship by air under IATA regulations.
References Svenstrup, N. et al.: Synthesis, 8, 809 (1994); Thibault, R. et al.: J. Am. Chem. Soc., 128, 12084 (2006);

Applications Labelled Ascorbic Acid. Physiological antioxidant. Coenzyme for a number of hydroxylation reactions; required for collagen synthesis. Widely distributed in plants and animals. Inadequate intake results in deficiency syndromes such as scurvy. Used as antimicrobial and antioxidant in foodstuffs.
References Al-Meshal, I.A., et al.: Anal. Profiles Drug Subs., 11, 45 (1982), Levine, M., et al.: N. Engl. J. Med., 314, 892 (1986), Prust, C., et al.: Nature Biotech., 23, 195 (2005),

Applications Isotope labelled analogue of D-Allose (A548006) is a rare naturally occurring monosaccharide, known to exert anti-proliferative effects on cancer cells.
References Jeong, R.U., et al.: Anal. Bioanal. Chem., 401, 689 (2011); Yamada, K., et al.: Nut. Res., 32, 116 (2012);

Applications 3-Pyridinecarboxaldehyde-d4 (cas# 258854-80-7) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications is the labeled analogue of Cyprodinil (C989060), which is a a broad-spectrum fungicide of the class of pyrimidinamines. It is commonly used for protection of cereal crops and fruits against fungal infections.
References Heye, U.J. et al.: Bright. Crop Prot. Conf., Pests Dis., 2, 501 (1994); Boric, B. et al.: Pesticidi, 12, 277 (1997); Knauf-Beiter, G. et al.: Plant Dis., 79, 1098 (1995);

Stability Hygroscopic
Applications Isotope labelled analogue of D-Fructose 6-Phosphate. β-D-form of D-Fructose 6-Phosphate is commonly found in cells within the glycolysis metabolic pathway produced by the isomerization of glucose 6-phosphate (G596805).
References Holder, J.W., et al.: PLoS. Genetics., 7, 1002219 (2011); Ikeguchi, Y., et al.: Anal. Sci., 9, 653 (1993);

Applications Isotope labelled L-Isomer of D-Idose (I175050), a monosaccharide that has is an important component of dermatan sulfate and heparan sulfate.
References Olsen, S.G., et al.: J. Biol. Chem., 264, 15982 (1989);