Deuterated Compounds

Applications 1,5-Diaminonaphthalene (D416415). Aromatic amines likely to have high carcinogenic potency. QSARs of aromatic amines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Franke, R., et al.: Carcinogenesis, 22, 1561 (2001), Benigni, R., et al.: Chem. Rev., 105, 1767 (2005), Benigni, R., et al.: Environ. Mol. Mutagen., 50, 152 (2009),

Applications α-(2,3-Dimethylphenyl)-α-methyl-1H-imidazole-5-methanol-d3 is the isotope labelled analog of α-(2,3-Dimethylphenyl)-α-methyl-1H-imidazole-5-methanol (D473780); a reagent in the synthesis of Medetomidine (M203250) which is an α2-adrenergic agonist. Also a sedative and analgesic.
References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987); Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987); Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988); Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996); Chen, W., et al.: Faming Zhuanli Shenqing. CN 101921234 A 20101222. Dec 22, 2010

Applications 1,3-Propane-d6-diamine, Dihydrochloride is used in the study of trimethylsilylated di and polyamine and their isotopically labelled analogs.
References Smith, R. G., et al.: J. Org. Chem., 43, 2178 (1978)

Applications 5alpha-Androstan-3beta-ol-17-one-16,16-d2 (CAS# 79037-35-7) is a useful isotopically labeled research compound.

Applications 2-Chloroethyl (2,6-Dimethylphenyl)-carbamic Acid Ester-d6 is an intermediate used in the synthesis of Dimethachlor Ethane Sulfonic Acid Sodium Salt-d6 (D460284), which is the deuterium labelled form of Dimethachlor Ethane Sulfonic Acid Sodium Salt (D460283), which is a pesticide metabolite and pollutant found in groundwater, surface water, and wastewater.
References Huntscha, S., et al.: J. Chromatogr. A, 1268, 74 (2012); Reemtsma, T., et al.: J. Chromatogr. A, 1271, 95 (2013);

Applications N,N′-Bis(3-aminopropyl)-1,3-propanediamine-d24 is labelled N,N′-Bis(3-aminopropyl)-1,3-propanediamine which is used to prepare topoisomerase inhibitors and antitumor agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gamage, S., et al.: J. Med. Chem., 44, 1407 (2001);

Applications Sodium Propionate-3,3,3-d3 (CAS# 1210410-35-7) is a useful isotopically labeled research compound. This compound can be used to demonstrate intereactions between ergosterol and amphotericin B in lipid bilayers using NMR spectroscopy to exert antifungal activity.
References Matsumori, N.,et.al., J.Am.Chem.Soc., 131,11855-11860,(2009);

Applications Pyrrole-d5 (CAS# 18430-85-8) is a useful isotopically labeled research compound.

Applications N2-Acetyl Acyclovir-d4 is the isotope labelled analog of N2-Acetyl Acyclovir (A168015); an impurity of Acyclovir (A192400) which is an orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Also an antiviral.
References Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979); Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988); Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992)

Applications Hexachloro-1,3-Butadiene (13c4, 99%) 100 Ug/Ml In Isooctane (cas# 93951-70-3) is a useful research chemical.

Applications n-Propyl-d7-benzene (CAS# 65087-58-3) is a useful isotopically labeled research compound.

Applications An intermediate in the production of labelled Enrofloxacin.
References Chao, Q., et al.: J. Med. Chem., 52, 7808 (2009), Bebbington, D., et al.: Bioorg. Med. Chem. Lett., 19, 3586 (2009),

Applications Potassium Tetradecanoate-d27 (CAS# 352438-87-0) is a useful isotopically labeled research compound.

Applications 1-Bromodecane-d21 (CAS# 98195-39-2) is a useful isotopically labeled research compound.

Applications (±)-N-(2,6-Dimethylphenyl)-1-iso-propyl-d7-2-piperidinecarboxamide (CAS# 1276197-11-5) is a useful isotopically labeled research compound.