Deuterated Compounds

Applications Vinblastine-d3 Methiodide is the labeled analogue of Vinblastine Methiodide (V314015), an adduct of Vinblastine (V314000), an antitumor alkaloid isolated from periwinkle, Vinca rosea Linn., Apocynaceae; inhibits microtubule assembly. An antineoplastic.
References Dorman, D.E., Paschal, J.W.: Org. Magnetic Resonance, 8, 413 (1976); Lu, C., et al.: Cancer Research, 39, 3575 (1979); Gobbi, P.G., et al.: J. Clin. Oncol., 14, 527 (1996); Muhtadi, F.J., et al.: Anal. Profiles Drug Subs. Excip., 21, 611 (1992)

Applications D,L-Carnitine-d3 Chloride is the isotope labelled analog of D,L-Carnitine Chloride (C184100); a vitamin (enzyme cofactor). It is an essential cofactor of fatty acid metabolism and is required for the transport of fatty acids through the inner mitochondrial membrane. Synthetized primarily in the liver and kidney with the highest concentrations found in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado.
References Mitchell, M.E., et al.: Am. J. Clin. Nutr., 31, 293 (1978); Lango, R., et al.: Cardiovasc. Res., 51, 21 (2001); Vaz, F.M., et al.: Biochem. J., et al.: 361, 417 (2002); Karlic, H., et al.: Nutrition, 20, 709 (2004)

Applications 2-Nonen-1-ol-D2 is a labelled analogue of 2-Nonen-1-ol. 2-Nonen-1-ol is an unsaturated alcohol that has antimicrobial properties. 2-Nonen-1-ol is also used as a flavour and fragrance agent, and has a “green” odour.
References Gigot, C., et al.: Biotechnol. Agron. Soc. Environ., 14, 451 (2010); Kalua, C., et al.: J. Agr. Food Chem., 53, 8054 (2005); Serrazanetti, D., et al.: Food Cont., 34, 336 (2013)

Applications 4-Aminopiperidine-3,3,4,5,5-d5 (CAS# 1219803-60-7) is a useful isotopically labeled research compound.

Applications 2-Bromofluorobenzene-d4 (CAS# 50592-35-3) is a useful isotopically labeled research compound.

Applications Oleic Acid Methyl Ester-d3 is labelled Oleic Acid Methyl Ester (M330110) which is an intermediate used to prepare cis-9,10-Epoxystearic Acid Methyl Ester, an inhibitor of soybean lipoxygenase.
References Wright, S., et al.: Bioorg. Med. Chem. Lett., 2, 1385 (1992)

Applications 2-(2-Aminoethoxy)anisole-d3 (cas# 1189881-28-4) is a compound useful in organic synthesis.

Applications Thiazole Orange-d3 is the isotope labelled analog of Thiazole Orange (T344135); a fluorescent DNA staining dye used for reticulocyte analysis.
References Lee, L.G., et al.: Cytometry, 7, 508 (1986); Cho, H., et al.: ACS Nano, 7, 2032 (2013)

Applications Ethyl-d5-methylamine (CAS# 1219804-73-5) is a useful isotopically labeled research compound.

Applications Butyl sodium sulfate-D9 is a labelled analogue of Butyl sodium sulfate (B693875). Butyl sodium sulfate is the sulfate salt of Monobutyl sulfate (M525130). Monobutyl sulfate is used as a wetting agent in the mercerization (a treatment that gives cotton its shiny appearance and also functions to increase its strength) of cotton. Monobutyl sulfate is also used in the polymerization of tetrahydrofuran.
References Pruckmayr, G. & Wu, T.: Macromolecules, 11, 662 (1978); Shenai, V., Int. Dyer Text. Print. Bleach. Finish., 158, 246 (1977)

Applications 2,6-Di-tert-butylphenol-13C6 , is the labeled analogue of 2,6-Di-tert-butylphenol (D494593).

Applications TRIS Maleate-d15 (CAS# 1219806-43-5) is a useful isotopically labeled research compound.

Applications Benzyl 2-(2-Hydroxy-3-morpholinopropyl)hydrazinecarboxylate-d5 is an intermediate for the synthesis of 2-NP-AMOZ-d5 (N894952), which is a labelled derivatized of AMOZ (A634600), a metabolite of Nitrofuran.
References Vroomen, L., et al.: Toxicol. Appl. Pharmacol., 95, 53 (1988), Delatour, T., et al.: J. Agric. Food Chem., 51, 6371 (2003), Stadler, R., et al.: Analyst, 129, 276 (2004),

Applications Sodium 2-Keto-4(R,S)-methyl-d3-pentanoate (CAS# 93523-67-2) is a useful isotopically labeled research compound.