Deuterated Compounds

<p>Applications Isotope labelled benzene, an organic compound that is a natural constituent of crude oil and one of the most basic petrochemicals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feng, Z.X.. et al.: J. Phys. Chem. Lett. 4, 285 (2013); Pilling. M., et al.: Chem. Eng. Prog., 108, 32 (2012);<br></p>

<p>Applications Labelled Tolazamide, an antidiabetic.<br>References Welling, et al.: J. Pharmac. Sci., 71, 1259 (1982);<br></p>

<p>Applications Labelled Ethylparaben. An antimicrobial agent used in cosmetic products.<br>References Gilliland, D., et al.: J. Appl. Bacteriol., 72, 258 (1992), Routledge, E., et al.: Toxicol. Appl. Pharmacol., 153, 12 (1998), Miller, C., et al.: J. Biol. Chem., 272, 32824 (1997), Nakagawa, Y., et al.: Biochem. Pharmacol., 55, 1907 (1998),<br></p>

<p>Stability Hygroscopic<br>Applications Labelled Cholesterol (C432501). Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones.<br>References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>

<p>Applications The microwace spectra of Dichloroacetic Acid-d1 consists of many weak absorption lines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Van Zoeren, E., et al.: J. Mol. Struct., 97, 315-322 (1983);<br></p>

<p>Applications N-Methyl-N’-nitrosopiperazine-d4 is the isotope labelled analog of N-Methyl-N’-nitrosopiperazine (M325800), which is used as a reagent in the organic synthesis of several compounds including that of (4-methoxyphenoxy)acetic and (3,4,5-trimethoxyphenoxy)acetic acid amides and hydrazides which display antimicrobial and anthelmintic properties and may act as potential neurotropic and cardiovascular agents. N-Methyl-N’-nitrosopiperazine also diplayed strong nasal carcinogenity and genotoxicity toward nasal cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Valenta, V., et al.: Collect. Czech. Chem. C., 52, 3013 (1987); Klein, R., et al.: Carcinogenesis, 20, 1629 (1999);<br></p>

<p>Applications 3-Hydroxypropionic Acid-D4 Sodium Salt is a deuterium labelled analogue of 3-Hydroxypropionic Acid Sodium Salt (H952480), which is beta hydroxy acid derived from plants and crops such as corn. 3-Hydroxypropionic Acid is used in the preparation of acrylates and biodegradable polymer polyester.<br>References Wang, Y. et al.: Biomacromol., 3, 828 (2002); Jiang, X. et al.: Appl. Microbiol. Biotech., 82, 995 (2009);<br></p>

<p>Applications Labelled Tiglic acid (T440050). Tiglic acid is the stable isomer of angelic acid. Tiglic acid was found as glyceride in croton oil, as butyl ester in the oil of the Roman camomile, and as geranyl tiglate in oil of geranium. Tiglic acid is formed during the charcoaling of maple wood.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bueding, et al.: J. Biol. Chem., 202, 505 (1953),<br></p>

<p>Applications Isosilybin A+B mixture - d3 is the isotope labelled mixture of Isosilybin A and Isosilybin B. Isosilybin (I901000) is useful in the treatment of liver disease.<br>References Parthasarathy, M.R., et al.: Phytochemistry, 18, 506 (1979),<br></p>

<p>Applications Carbon 13 Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>

<p>Applications The labelled analogue of a versatile ethylenediamine derivative used as an intermediate in the organic synthesis of neurochemicals, antitumor agents and other pharmaceutical compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Squires, R.F. et al.: Neurochem. Res., 18, 787 (1993); Murdock, K.C. et al.: J. Med. Chem., 22, 1024 (1974);<br></p>

<p>Applications 4-Bromophenol-2,3,5,6-d4 is the labelled analogue of 4-Bromophenol (B686405) which is used as a reagent in Stille reactions.<br>References Littke, A.F. et al.: J. Am. Chem. Soc., 124, 6343 (2002);<br></p>

<p>Applications Labelled analogue of Potassium Cyanide, a reagent widely used in organic synthesis for the preparation of nitriles and carboxylic acids, particularly in the von Richter reaction.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kollenz, G. et al.: Org. Prep. Proc. Int., 12, 244 (1980); Subramanian, L. R.: Sci. Synth., 19, 173 (2004);<br></p>

<p>Applications Useful for diagnostic determination of Melamine and related compounds in kidney tissue.<br>References Mast, R., et al.: Food Chem. Toxicol., 21, 807 (1983), Yokley, R., et al.: J. Agric. Food Chem., 48, 3352 (2000), Ehling, S., et al.: Food Addit. Contam., 24, 1319 (2007), Vail, T., et al.: J. Anal. Toxicol., 31, 304 (2007),<br></p>

<p>Applications Labelled Methylparaben (M325660). It is used as preservative in foods, beverages and cosmetics.<br>References Goodwin, M., et al.: Science, 203, 559 (1979),<br></p>

<p>Applications Hexazinone-d6 (dimethyl-d6-amino) (CAS# 1219804-22-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications Labelled Bis(2-ethylhexyl)phthalate. Bis(2-ethylhexyl) Phthalate plasticizer is used to impart softness and flexibility to PVC products.<br>References Heindel, J., et al.: Toxicol. Appl. Pharmacol., 115, 116 (1992), Kasahara, E., et al.: Biochem. J., 365, 849 (2002), Lee, B., et al.: J. Toxicol. Environ. Health, 70, 1365 (2007),<br></p>

<p>Applications Methyl 2-Hydroxybenzoate-3,4,5,6-d4 (CAS# 1219802-12-6) is a useful isotopically labeled research compound.<br></p>

<p>Stability Volatile<br>Applications 2,5-Dimethylfuran-d6, is the labelled 2,5-Dimethylfuran (D473050). It is an ideal marker for detecting cigarette smoke.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Spitzer, W., et al.: Clin. Invest. Med., 13, 17 (1990), Alonso, M., et al.: Anal. Bioanal. Chem., 396, 2989 (2010),<br></p>