Deuterated Compounds

<p>Applications Cyclopropylmethyl-d2 Alcohol (CAS# 90568-07-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications n-Dodecyl-d25-phosphocholine (CAS# 861924-55-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2,2'-Bipyridyl-d8 was a useful compound in the NMR study of soft porous nanocrystal and a bulk crystal.<br>References Hijikata, Y., et al.: Chem. Commun. (Cambridge, UK), 47, 7632 (2011)<br></p>

<p>Applications 3-Hydroxypropionic Acid-13C3 Sodium Salt is isotope labelled analogue of 3-Hydroxypropionic Acid Sodium Salt (H952480), which is beta hydroxy acid derived from plants and crops such as corn. 3-Hydroxypropionic Acid is used in the preparation of acrylates and biodegradable polymer polyester.<br>References Wang, Y. et al.: Biomacromol., 3, 828 (2002); Jiang, X. et al.: Appl. Microbiol. Biotech., 82, 995 (2009);<br></p>

<p>Applications Labelled Methyl Methanethiosulfonate (M321500). Used for the rapid and selective modification of sulfhydryl groups of enzymes. Useful for mapping the pore-lining regions of the ryanodine receptor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stauffer, D.A., and Karlin, A.: Biochemistry, 33, 6840 (1994), Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996), Ehrlich, B.E., et al.: J. Gen. Physiol., 109, 255 (1997), Dunten, R.L., et al.: Biochemistry, 32, 3139-3145 (1993)<br></p>

<p>Stability Volatile<br>Applications N-Hexane (D14, 98%) (cas# 21666-38-6) is a useful research chemical.<br></p>

<p>Applications Potassium Hexadecanoate-2,2-d2 (CAS# 203805-86-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Methylurea-d6 is the labelled form of N-Methylurea (M338175). N-Methylurea is used as a reagent in the synthesis of bis(aryl)(hydroxyalkyl)(methyl)glycoluril derivatives and is a potential byproduct of caffeine.<br>References Antonova, M.M., et al.: Chem. Heterocycl. Comp., 50, 503 (2014); Zarrelli, A., et al.: Sci. Total Environ., 470, 453 (2014)<br></p>

<p>Applications 3-Chlorobenzoic-d4 Acid (CAS# 2098655-72-0) is a useful isotopically labeled research compound. The compound can be used to prepare isotopically enriched analogs for treating and preventing thrombosis.<br>References Pandey, A., et.al., PCT Int. Appl., 51,(2017);<br></p>

<p>Applications Used for preparation of phthalide derivatives for treatment of diabetes.<br></p>

<p>Applications 1,3-Dihydroxybenzene-d6 (CAS# 70938-00-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications The labelled analogue of Diethylcarbamazine Citrate (D443900).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References MacKenzie, C.D. et al.: Trop. Dis. Bull., 82, R1 (1985); Harned et al.: Ann. N.Y. Acad. Sci., 50, 141 (1948);<br></p>

<p>Applications 2-Ethylphenol-d10 (CAS# 721429-63-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications L-Lysine-DL-amphetamine-d6 2HCl (propane-1,1,2,3,3,3-d6) (CAS# 1276056-89-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications L-4-Hydroxyphenyl-3,5-d2-alanine (CAS# 30811-19-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Bis(2-methylpentyl) Phthalate-d4, is the labeled analogue of Bis(2-methylpentyl) Phthalate (B486005), used as a plasticizer to impart softness and flexibility to PVC products.<br>References Pierson, J. F., et al.: Angewandte Makromolekulare Chemie, 38, 167 (1979); Kaya, T., et al.: Chem. Res. Toxic., 19 (8), 999 (2006); Matter, H., et al.: Bioorg. Med. Chem., 20 (18), 5352 (2012);<br></p>

<p>Applications Anthracene-d10 is an isotope labelled analogue of Anthracene (A678400), an polycyclic aromatic hydrocarbon found readily as an component in coal tar. Anthracene is also used in the preparation of various dyes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications A labelled major (toxic) metabolite of Styrene (S687790), catalyzed by epoxide hydrolase.<br>References Shen, S. et al.: Drug Metab. Disp., 38, 1934 (2010); Carlson, G.P. et al.: J. Toxicol. Env. Health, 73, 1689 (2010)<br></p>

<p>Applications A labelled derivative of D-Mannosamine (M167000).<br>References Pukanud, P. et al.: Drug Delivery, 16, 289 (2009);<br></p>

<p>Applications 2-Naphthylhydrazine-D3 is an intermediate used in the synthesis of Indocyanine Green-d12 (I697002), which is an isotopic analog of Indocyanine Green (I697000), a tricarbocyanine type of dye with infrared absorbing properties that can be used as a diagnostic aid (blood volume determination, cardiac output, hepatic function).<br>References Papageorgiou, P., et al.: Br. J. Dermatol., 142, 973 (2000), Dreno, B., et al.: Dermatology, 203, 135 (2001), Gollnick, H., et al.: Drugs, 63, 1579 (2003), Seaton, E., et al.: Lancet, 362, 1347 (2003)<br></p>

<p>Applications Potassium Hexadecanoate-d31 (CAS# 63074-47-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Hydroxyadamantane-d15 (CAS# 33830-11-4) is a useful isotopically labeled research compound. This compound can be used to treat viral diseases.<br>References Atkinson, J., et.al., Can., 16, (1971);<br></p>

<p>Applications Di(methyl-d3)dimyristylammonium Chloride is labelled Dimethyldimyristylammonium Chloride (D472560) which is used as a surfactant.<br>References Cipiciani, A., et al.: Austr. J. Chem., 44, 1505 (1991); Hueck, H., et al.: Appl. Microbiol., 14, 308 (1966)<br></p>

<p>Applications 7,9-Di-tert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione-13C6, is a labeled analogue of 7,9-Di-tert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione (D493755), an antioxidant naturally found in aerial parts of Gmelina asiatica Linn (Verbenaceae). It is also found in essential oils of some Stachys species from Mediterranean area. It is an impurity of Irganox 1098 (A697523) used in the food packaging.<br>References Merlin, N., et al.: Pharmacogn. Res., 1, 152 (2009); Conforti, F., et al.: Food Chem., 116, 898 (2009), Riquet, A. et al.: Food Chem., 199, 59 (2016);<br></p>

<p>Applications 8-Bromo-7-ethyl-3,7-dihydro-3-methyl-1H-purine-2,6-dione-d5, is the labeled analogue of (B684895), which is a substituted derivative of Xanthine (X499950).<br>References Mueller, C. et. al: Handbook Exp. Pharmacol. 200,151(2011)<br></p>

<p>Applications m-Xylene-alpha,alpha,alpha,alpha',alpha',alpha'-d6 (CAS# 29636-65-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications Proven to be an extremely potent and selective a-D-galactosidase inhibitor.<br>References Paulsen, H., et al.: Chem. Ber., 113, 2601 (1980),<br></p>

<p>Applications Butoxy-d9-acetic Acid (CAS# 669720-55-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications A labelled Voriconazole (V760000) impurity.<br>References Rieke, R., et al.: Science, 246, 1260 (1989), Dickinson, R., et al.: Bioorg. Med. Chem. Lett., 6, 2031 (1996),<br></p>

<p>Applications Biphenyl-4,4'-d2 (CAS# 6120-99-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications n-Propyl-1,1,3,3,3-d5 Alcohol (CAS# 188894-71-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications Tetraethylcystamine-13C8 is the isotope labeled form of Tetraethylcystamine (T291435), which is a reagent used in the addition of Thiobistriethylamine.Also, it is an intermediate used in the synthesis of Tiamulin-13C4 Fumarate (T436603), which is labeled Tiamulin (T436600); a derivative of Pleuromutilin; anti-bacterial.<br>References Evers, M., et al.: Bioorg. Med. Chem. Lett., 13, 4415 (2003); Egger, H., et al.: J. Antibiot., 29, 923 (1976), Baughn, C.O., et al.: Avian Dis., 22, 620 (1978), Goodwin, R.F., et al.: Vet. Rec., 104, 194 (1979), Kitai, K., et al.: Antimicrob. Agents Chemother., 31, 1935 (1987), Aarestrup, F., et al.: Vet. Microbiol., 64, 299 (1999)<br></p>

<p>Applications 4-Chlorobenzamide-2,3,5,6-d4 (CAS# 1219794-65-6) is a useful isotopically labeled research compound.<br></p>

<p>Stability Volatile<br>Applications 1-Butan-d9-ol is the labeled form of 1-Butanol, which is used for the production of dimethylfuran for liquid fuels.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Roman-Leshkov, Y. et al.: Nature, 447, 982 (2007);<br></p>